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A couple of NFC West opponents battle on Sunday, September 17, 2023 at SoFi Stadium when the San Francisco 49ers (1-0) and the Los Angeles Rams (1-0) match up.
49ers vs. Rams Odds
Point Spread
The spread for this matchup is set at 7.5 points, with oddsmakers listing the 49ers as the favorites.
Moneyline
As for the moneyline, the 49ers have -340 odds to pick up the win, while the Rams are listed at +270 to claim victory.
Over/Under
Finally, the total for the game is set at 45 points.
Game Info
How to Watch 49ers vs. Rams Live?
- Game Day: Sunday, September 17, 2023
- Game Time: 4:05 PM ET
- TV Channel: FOX
- Location: Inglewood, California
- Stadium: SoFi Stadium
Betting Preview
49ers
The 49ers averaged 3.9 more points last year (26.5) than the Rams allowed (22.6). In games where the 49ers scored more than 22.6 points last season, they were 20-2 overall and 18-4 against the spread.
The 49ers accumulated 365.6 yards per game last season, 24.5 more than the Rams allowed (341.1). The 49ers picked up 5.9 yards per play, while the Rams gave up 5.5.
In contests where the 49ers offense accumulated more than the Rams’ average yard allowance last season (341.1), they were 16-8 against the spread and 20-4 overall.
Rams
The Rams put roughly the same amount of points on the board per game (18.1) as the 49ers gave up (16.3) last year. In games when the Rams scored more than 16.3 points last season, they were 10-6 overall and 10-6 against the spread. The Rams’ offense gained 280.5 yards per game last year, 20.1 yards fewer than the 300.6 given up by the 49ers’ defense. The Rams accumulated 4.8 yards per play, while the 49ers conceded 5.
When the Rams offense put together a game with more than the 49ers’ average yardage allowed (300.6) last season, the team was 8-6 overall and 8-6 against the spread.
49ers vs. Rams Injury Report
49ers
| Player | Pos. | Injury | Status |
|---|---|---|---|
| Tyrion Davis-Price | RB | Gameday inactive | Out |
| Samuel Womack | CB | Knee | Out |
| Brandon Allen | QB | Gameday inactive | Out |
| Jalen Graham | LB | Gameday inactive | Out |
Rams
| Player | Pos. | Injury | Status |
|---|---|---|---|
| Cam Akers | RB | Gameday inactive | Out |
| Ernest Jones | LB | Illness | Probable |
| Russ Yeast | DB | Knee | Probable |
| Desjuan Johnson | DE | Gameday inactive | Out |
| Stetson Bennett | QB | Not injury related | Out |
| Jason Taylor II | DB | Groin | Out |
| Puka Nacua | WR | Oblique | Probable |
| Zach Evans | RB | Gameday inactive | Out |
49ers vs. Rams Betting Analysis
49ers Betting Insights
Against the spread, the 49ers were 11-6-0 last year. The 49ers went 5-2 as 7.5-point favorites or greater last year.
Out of 17 49ers games last year, nine went over the total.
Rams Betting Insights
The Rams’ record against the spread last year was 6-9-2. The Rams didn’t have a win ATS (0-1-1) as 7.5-point or larger underdogs last season.
Last season, Los Angeles was the underdog 11 times and won two of those games. Last season, Los Angeles was at least a +270 underdog on the moneyline two times, losing each of those contests. In 17 Rams games last season, six of them went over the total.
The Rams were underdogs in 11 games last season and won two (18.2%) of those contests. Last season, the Rams were at least a +270 underdog on the moneyline two times, losing each of those contests.
49ers vs. Rams Against The Spread & Betting Records
49ers
| Overall | Home | Away | |
|---|---|---|---|
| Point Total AVG | 42.2 | 42.3 | 42.2 |
| Implied Team Total AVG | 23.9 | 24.2 | 23.5 |
| ATS Record | 11-6-0 | 7-2-0 | 4-4-0 |
| Over/Under Record | 9-8-0 | 5-4-0 | 4-4-0 |
| Moneyline Favorite Record | 12-3 | 8-0 | 4-3 |
| Moneyline Underdog Record | 1-1 | 0-1 | 1-0 |
Rams
| Overall | Home | Away | |
|---|---|---|---|
| Point Total AVG | 42.2 | 42.1 | 42.4 |
| Implied Team Total AVG | 23.9 | 23.8 | 24.1 |
| ATS Record | 6-9-2 | 4-5-0 | 2-4-2 |
| Over/Under Record | 6-11-0 | 5-4-0 | 1-7-0 |
| Moneyline Favorite Record | 3-3 | 2-3 | 1-0 |
| Moneyline Underdog Record | 2-9 | 2-2 | 0-7 |
Players to Watch
49ers
- Christian McCaffrey averaged 67 rushing yards per game last year (1,139 total yards to rank eighth in the NFL,) while scoring eight rushing touchdowns.
- McCaffrey’s offensive contributions include 85 receptions (five per game) on 108 targets for 741 yards (43.6 per game) and five receiving touchdowns.
- Brandon Aiyuk had 78 catches for 1,015 yards and eight receiving touchdowns. He was targeted 114 times and averaged 4.6 receptions per game over 17 games played.
- Last season, George Kittle caught 60 passes for 765 receiving yards with 11 touchdowns in the passing game (third in the NFL). He was targeted 86 total times and averaged four receptions per game over 15 games played.
- Deebo Samuel had 56 catches for 632 yards and two receiving touchdowns. He averaged 4.3 yards per game over 13 games and was targeted 94 times.
- Nick Bosa had 51 tackles, 19 TFL, 18.5 sacks, and one pass defended in 2022.
- Fred Warner had 130 tackles, three TFL, two sacks, and one interception.
- During the 2022 campaign, Dre Greenlaw had 127 tackles, three TFL, and one interception over 15 games.
- Talanoa Hufanga’s stat sheet included four interceptions as well as 95 tackles, five TFL, two sacks, and nine passes defended in 17 games
Rams
- In nine games last season, Matthew Stafford passed for 2,087 yards (231.9 yards per game) while recording 10 touchdowns, eight interceptions and a 68% completion percentage.
- Stafford made an impact with his legs, too, scrambling for 9 yards and one TD.
- Tyler Higbee was a big contributor, totaling 620 receiving yards and three touchdowns on 72 receptions.
- In 17 games with the Ravens last season, Demarcus Robinson converted 75 targets into 48 catches, 458 yards and two touchdowns.
- Van Jefferson was targeted 44 times leading to 24 catches, 369 yards and three touchdowns in 11 games.
- Last year with the Browns, John Johnson recorded 96 tackles, four TFL, 0.5 sacks, and one interception in 17 games.
- Ernest Jones, who played in 17 games, delivered four TFL, 113 tackles, and one interception.
- Aaron Donald helped on defense with 49 tackles, 10 TFL, five sacks, and two passes defended in 11 games.
- Michael Hoecht was an important contributor on D last year, with 34 tackles, four TFL, and 4.5 sacks.
49ers vs. Rams Predictions and Pick
Our pick to win this game is the 49ers, and we expect that Rams will cover the spread (49ers -7.5). Finally, we see the scoring in this one going under the posted total of 45 points.
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