Patriots vs Cardinals Prediction: Week 14 Picks, Live Odds & Start Time – December 12, 2022

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The Arizona Cardinals (4-8) stay home at State Farm Stadium on Monday, December 12, 2022 to play the New England Patriots (6-6).

Patriots vs. Cardinals Odds

Point Spread

The spread for this matchup is set at 2 points, with bookmakers listing the Patriots as the favorites.


As for the moneyline, the Patriots have -130 odds to pick up the win, while the Cardinals are listed at +110 to claim victory.


Finally, the total for the game is set at 43.5 points.

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Game Info

How to Watch Patriots vs. Cardinals Live?

  • Game Day: Monday, December 12, 2022
  • Game Time: 8:15 PM ET
  • TV Channel: ESPN
  • Location: Glendale, Arizona
  • Stadium: State Farm Stadium

Betting Preview


The Patriots are averaging 318.9 yards per game on offense this year (24th in NFL), and they are giving up 311.8 yards per game (seventh) on defense. The Patriots are compiling 20.8 points per game on offense, which ranks them 19th in the NFL. On the defensive side of the ball, they rank seventh, giving up 18.8 points per game.

On offense, the Patriots rank 20th in the NFL with 214 passing yards per game. Meanwhile, they rank ninth in passing yards allowed per contest (200.6). On offense, the Patriots rank 23rd in the NFL with 104.9 rushing yards per game. Meanwhile, they rank 12th in rushing yards allowed per contest (111.2).

The Patriots are averaging a 36.2% third-down percentage on offense this year (25th in NFL), and they are surrendering a 40.4% third-down percentage (19th) on defense. The Patriots are gaining 5.4 yards per play (18th in the league), while allowing 5 per play on the defensive side of the ball (sixth in the NFL) this season. The Patriots have forced 19 total turnovers (seventh in NFL) this season and have turned it over 17 times (22nd in NFL) for a turnover margin of +2, 10th-ranked in the league.

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From an offensive perspective, the Cardinals are generating 334.8 total yards per contest (20th-ranked). They rank 21st in the NFL on the other side of the ball (356.2 total yards allowed per game). The Cardinals have not been getting things done on defense, ranking second-worst with 26.8 points allowed per game. They have been better on the other side of the ball, generating 22 points per contest (16th-ranked).

The Cardinals rank 17th in the NFL with 219.8 passing yards per game on offense, and they rank 24th with 245.4 passing yards allowed per contest on defense. In terms of rushing, the Cardinals rank 21st in the NFL on offense (114.9 rushing yards per game) and 11th on defense (110.8 rushing yards allowed per contest).

The Cardinals have been struggling on third down, ranking fifth-worst with a 45% third-down conversion rate allowed per game. They have been more effective on offense, regstering a 37.7% third-down rate (24th-ranked). From an offensive standpoint, the Cardinals are posting 4.9 yards per play (27th-ranked). They rank 20th in the NFL on the other side of the ball (5.7 yards given up per play). After forcing 14 turnovers (19th in NFL) and turning the ball over 13 times (ninth in NFL) this season, the Cardinals have the 13th-ranked turnover margin of +1.

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Patriots vs. Cardinals Injury Report


Player Pos. Injury Status
Damien Harris RB Thigh Doubtful
Jakobi Meyers WR Head Out
Jalen Mills CB Groin Out


Player Pos. Injury Status
Zach Allen DE Illness Questionable
Byron Murphy CB Back Out
Jonathan Ledbetter DE Back Questionable
Rondale Moore WR Groin Out

Patriots vs. Cardinals Betting Analysis

Patriots Betting Insights

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The Patriots have covered the spread six times over 12 games with a set spread. In games they were favored in by 2 points or more so far this season, the Patriots went 4-1-1 against the spread.

Patriots games have finished with a final combined score above the over/under five times this season. The Patriots finished with an 8-4 record in games they were favored on the moneyline last season (winning 66.7% of those games).

The Patriots had an 8-3 record last year (winning 72.7% of their games) when they played as a moneyline favorite of -130 or shorter.

Cardinals Betting Insights

The Cardinals are 6-6-0 against the spread this year. In games they have played as 2-point underdogs or more, the Cardinals have an ATS record of 4-4.

This season, Cardinals games have hit the over six times. This season, the Cardinals have been the underdog nine times and won three of those games.

The Cardinals have a record of 2-6 in games where sportsbooks have them as underdogs of at least +110 on the moneyline.

Patriots vs. Cardinals Against The Spread & Betting Records


Overall Home Away
Point Total AVG 42.1 42.4 41.8
Implied Total AVG 23.3 23.3 23.2
ATS Record 6-5-1 3-3-0 3-2-1
Over/Under Record 5-7-0 2-4-0 3-3-0
Moneyline Favorite Record 5-1 3-1 2-0
Moneyline Underdog Record 1-5 0-2 1-3


Overall Home Away
Point Total AVG 47.5 48 46.7
Implied Total AVG 25.7 26.3 24.8
ATS Record 6-6-0 3-4-0 3-2-0
Over/Under Record 6-5-1 4-2-1 2-3-0
Moneyline Favorite Record 1-2 1-1 0-1
Moneyline Underdog Record 3-6 0-5 3-1

Players to Watch


  • On the ground, Rhamondre Stevenson averages 4.6 yards per attempt (19th in the NFL) and 61.2 yards per game for 734 total rushing yards. He has scored four rushing touchdowns this season.
  • He has also caught 56 passes (on 68 targets) for 383 receiving yards with one touchdown. He’s averaging 31.9 receving yards and 4.7 catches per game.
  • Mac Jones has 1,963 passing yards, seven touchdowns and seven interceptions this year. He has completed 68.1% of his attempts, averaging 218.1 yards per game and 7.3 per attempt.
  • He has also rushed for 88 yards (third on the Patriots) and added one touchdown on the ground, while averaging 9.8 rushing yards per game.
  • Damien Harris‘ output on the ground this season includes 383 yards and three TDs. He’s averaging 42.6 yards per game and 4.6 per attempt (19th in the NFL).
  • DeVante Parker averages 2.1 receptions and 39.6 yards per game, and has 436 total receiving yards and 23 catches. He’s gotten 38 total targets, and has caught one touchdown pass.
  • On defense, Matthew Judon has 44 tackles, 10 TFL, 13 sacks, and three passes defended in 2022.
  • Deatrich Wise has 6.5 sacks (third on the Patriots) to go with six TFL and 45 tackles.
  • Ja’Whaun Bentley has collected 73 tackles, two TFL, two sacks, and one interception this year. His tackle total leads the Patriots.
  • Jonathan Jones has 41 tackles and three interceptions on the year.


  • Through 10 games played this year, Kyler Murray has totaled 2,359 passing yards, with 14 touchdowns against seven interceptions and completing 66.3% of his attempts.
  • On the ground, Murray has added three rushing touchdowns and 415 rushing yards (second on the Cardinals).
  • James Conner has scored four rushing touchdowns, while totaling 476 rushing yards (3.9 per carry and 52.9 per game).
  • Conner has added 27 receptions (3 per game) for 171 yards (19 per game) with one receiving touchdown. He’s been targeted 35 times in the passing attack.
  • This season, DeAndre Hopkins has caught 49 passes for 574 receiving yards with three touchdowns through the air. He has been targeted 64 total times and is averaging 8.2 receptions per game through six games played.
  • Marquise Brown has 531 receiving yards and three touchdowns from 49 receptions after receiving 72 targets.
  • Zaven Collins has intercepted one pass in addition to 75 tackles, five TFL, two sacks, and four passes defended in 2022.
  • Isaiah Simmons has three sacks in addition to his four TFL, 60 tackles, and one interception through 12 games.
  • Budda Baker has one TFL, 90 tackles, and one interception.
  • Jalen Thompson has registered 66 tackles and one interception through 12 games.

Patriots vs. Cardinals Predictions and Pick

Our pick to win this matchup is the Patriots, and we predict that Patriots will cover the spread (Patriots -2). Finally, we see the scoring in this one going over the posted total of 43.5 points.

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How to Bet on Patriots vs. Cardinals

You can bet on Patriots vs. Cardinals at every legal online sportsbook. For more NFL odds, including moneylines, spreads, over/under totals as well as NFL prop odds, check out the latest NFL lines as well as our guide to the best NFL betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Patriots vs. Cardinals picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on football? Check out our complete guide to sports betting.


Luis Escalante

Luis has been a regular contributor to 4for4 since 2014 and is currently the Director of Strategy at Betsperts Group. Luis comes from an analytics background, leveraging his data skills with multiple years of experience in NFL, fantasy football, daily fantasy sports, and betting.

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