Toledo vs. Buffalo Prediction: Picks & Start Time – October 2022

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MAC opponents will clash when the Toledo Rockets (5-2) meet the Buffalo Bulls (4-3).

Toledo vs. Buffalo Odds

Point Spread

The spread for this matchup is set at 7.5 points, with bookmakers listing Toledo as the favorites.


As for the moneyline, Toledo has -287 odds to pick up the win, while Buffalo is listed at +219 to claim victory.


Finally, the total for the game is set at 56.5 points.

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Game Info

How to Watch Toledo vs. Buffalo Live?

  • Game Day: Saturday, October 22, 2022
  • Game Time: 1:00 PM ET
  • TV Channel: ESPN+
  • Location: Buffalo, New York
  • Stadium: UB Stadium

Betting Preview


On offense, Toledo ranks 68th in the FBS with 403.1 yards per game. Meanwhile, its defense ranks 50th in total defense (359.0 yards allowed per contest). Offensively, Toledo has been a top-25 unit, ranking 22nd-best in the FBS by averaging 38.4 points per game. The Rockets rank 68th on defense (26.3 points allowed per game). Toledo ranks 100th in pass offense (209.9 passing yards per game) and 28th in pass defense (194.4 passing yards allowed per game) this year. Toledo is totaling 193.3 rushing yards per game on offense (32nd in the FBS), and ranks 91st on the other side of the ball with 164.6 rushing yards allowed per game. Toledo is putting up a 41.9% third-down conversion rate on offense, which ranks them 57th in the FBS. On defense, the defense ranks 60th, surrendering a 37.5% third-down percentage. With 11 forced turnovers (43rd in the FBS) against nine turnovers committed (57th in the FBS), Toledo’s +2+2 turnover margin ranks 43rd in college football.


With 398.7 total yards per game on the offensive side of the ball, Buffalo ranks 71st in the FBS in 2022. Defensively, it ranks 74th, allowing 384.7 total yards per contest. Buffalo is generating 30.4 points per contest on offense this season (62nd-ranked). Meanwhile, it is surrendering 24.4 points per game (56th-ranked) on defense. In terms of passing, Buffalo ranks 68th in the FBS (241.6 passing yards per game) and 53rd defensively (216.6 passing yards allowed per contest). Buffalo is accumulating 157.1 rushing yards per contest on offense this season (62nd-ranked). Meanwhile, it is allowing 168.1 rushing yards per contest (93rd-ranked) on defense. From an offensive perspective, Buffalo is putting up a 39.4% third-down conversion percentage (68th-ranked). It ranks 32nd in the FBS defensively (33.0% third-down rate allowed). With 11 forced turnovers (43rd in the FBS) and nine turnovers committed (57th in the FBS) this season, Buffalo ranks 43rd in the FBS with a turnover margin of +2.

Toledo vs. Buffalo Betting Analysis

Toledo Betting Insights

Toledo is 4-2-0 against the spread this season. Toledo has a perfect 2-0 ATS record when playing as at least 7.5-point favorites. Games involving Toledo have hit the over four times this season. The Rockets have been the moneyline favorite five total times this season. They’ve gone 4-1 in those games. The Rockets have played as a moneyline favorite of -287 or shorter in only one game this season, which they won.

Bulls Betting Insights

Buffalo have compiled a 6-1-0 record against the spread this season. In games it has played as 7.5-point or bigger underdogs, Buffalo has an ATS record of 3-0. This season, three Buffalo games have gone over the point total. The Bulls have won one of the three games they’ve played as underdogs this season. This season, the Bulls have been at least a +219 underdog on the moneyline two times, losing each of those contests.

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Toledo vs. Buffalo Against The Spread & Betting Records


Overall Home Away
Point Total AVG 55.5 55.7 55.3
Implied Total AVG 34.8 35.0 34.7
ATS Record 4-2-0 3-0-0 1-2-0
Over/Under Record 4-2-0 2-1-0 2-1-0
Moneyline Favorite Record 4-1 3-0 1-1
Moneyline Underdog Record 0-1 0-0 0-1


Overall Home Away
Point Total AVG 55.4 51.0 57.2
Implied Total AVG 32.9 27.5 35.0
ATS Record 6-1-0 1-1-0 5-0-0
Over/Under Record 3-4-0 1-1-0 2-3-0
Moneyline Favorite Record 3-1 1-1 2-0
Moneyline Underdog Record 1-2 0-0 1-2

Players to Watch


  • As part of the Rockets’ defense, Dallas Gant has recorded 49 tackles and 4.0 TFL in seven games.
  • With 44 tackles, 3.0 TFL, and one pass defended in seven games, Dyontae Johnson has been an important piece of the Rockets’ defensive unit in 2022.
  • With 16 tackles, 2.0 TFL, and four interceptions in seven games, Quinyon Mitchell has been a significant piece of the Rockets’ defense in 2022.
  • Nate Bauer, as part of the Rockets’ defensive unit, has totaled 2.0 TFL, 30 tackles, and one interception in seven games.


  • Shaun Dolac has totaled 57 tackles, 5.0 TFL, and one sack in seven games for the Bulls.
  • In seven games for the Bulls, James Patterson has totaled one interception to go with 31 tackles, 3.0 TFL, one sack, and one pass defended.
  • Jahmin Muse has 0.5 sacks to go with 1.0 TFL, 15 tackles, and one interception in seven games.
  • With two interceptions to go with 23 tackles and three passes defended in seven games, Marcus Fuqua has been making a big difference on defense for the Bulls.

Toledo vs. Buffalo Predictions and Pick

Toledo vs. Buffalo betting card

    Pick ATS:

    Bulls (+7.5)

    Pick OU:

    Over (56.5)

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How to Bet on Toledo vs. Buffalo

You can bet on Toledo vs. Buffalo at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Toledo vs. Buffalo picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this matchup is Buffalo, and we predict that Buffalo will cover the spread (Toledo -7.5). Finally, we see the scoring in this one going over the posted total of 56.5 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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