USC vs. Colorado Prediction: Picks & Start Time – November 2022

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Pac-12 foes will clash when the No. 8 USC Trojans (8-1) battle the Colorado Buffaloes (1-8).

USC vs. Colorado Odds

Point Spread

The spread for this matchup is set at 34 points, with sportsbooks listing USC as the favorites.

Over/Under

Finally, the total for the game is set at 65.5 points.

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Game Info

How to Watch USC vs. Colorado Live?

  • Game Day: Friday, November 11, 2022
  • Game Time: 9:30 PM ET
  • TV Channel: Fox Sports 1
  • Location: Los Angeles, California
  • Stadium: Los Angeles Memorial Coliseum

Betting Preview

USC

USC ranks 95th in total defense this season (409.2 yards allowed per game), but has been playing really well on the offensive side of the ball, ranking ninth-best in the FBS with 495.9 total yards per game. USC sports the 60th-ranked defense this year (25.2 points allowed per game), and has been more effective on offense, ranking seventh-best with 41.0 points per game. USC has struggled on defense against the pass, ranking 23rd-worst in the FBS (267.0 passing yards allowed per game) this season. However, the Trojans rank 13th-best on the other side of the ball, putting up 313.7 passing yards per game. USC is totaling 182.2 rushing yards per game on offense this year (44th in the FBS), and is surrendering 142.2 rushing yards per game (64th) on defense. USC has struggled on defense in terms of third-down efficiency, ranking 25th-worst in the FBS (43.1% third-down percentage) this season. With the ball, however, the Trojans ranks fourth-best, putting up a 53.3% third-down conversion rate. USC has the best turnover margin in college football at +17, forcing 18 turnovers (17th in the FBS) while turning it over one time (first in the FBS).

Colorado

Colorado has lots of room to get better, as it ranks 10th-worst in total yards per game (303.2) and fourth-worst in total yards allowed per game (483.2). This season has been tough for Colorado on both offense and defense, as it is averaging only 15.6 points per game (third-worst) and allowing 40.2 points per game (second-worst). Colorado’s passing game has been sputtering, ranking 23rd-worst in the FBS with 189.4 passing yards per game. It has been more effective on the defensive side of the ball, giving up 250.7 passing yards per contest (94th-ranked). Colorado has lots of room to improve in the running game, as it ranks 23rd-worst in rushing yards per game (113.8) and second-worst in rushing yards allowed per game (232.6). Colorado has been struggling on third down, ranking worst with a 51.8% third-down conversion rate allowed per game. It has been more effective on the other side of the ball, putting up a 35.2% third-down rate (100th-ranked). After forcing eight turnovers (118th in the FBS) and turning the ball over 18 times (114th in the FBS) this season, Colorado owns the 100th-ranked turnover margin of -10.

USC vs. Colorado Betting Analysis

USC Betting Insights

USC has covered the spread five times over nine games with a set spread. Games involving USC have hit the over six times this season. The Trojans have not yet lost a game they played as the moneyline favorite this season, going 8-0. The Trojans have never played a game this season with moneyline odds of or shorter.

Buffaloes Betting Insights

Colorado has covered the spread just two times over nine games with a set number. This season, Colorado games have hit the over six times. This season, the Buffaloes have won one out of the nine games in which they’ve been the underdog. The Buffaloes have a record of 1-5, a 11.1% win rate, when they’re set as an underdog of or more by bookmakers this season.

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USC vs. Colorado Against The Spread & Betting Records

USC

Overall Home Away
Point Total AVG 66.0 63.7 68.9
Implied Total AVG 40.6 42.2 38.5
ATS Record 5-4-0 3-2-0 2-2-0
Over/Under Record 6-3-0 3-2-0 3-1-0
Moneyline Favorite Record 8-0 5-0 3-0
Moneyline Underdog Record 0-1 0-0 0-1

Buffaloes

Overall Home Away
Point Total AVG 53.2 55.1 50.9
Implied Total AVG 36.9 37.4 36.3
ATS Record 2-7-0 2-3-0 0-4-0
Over/Under Record 6-3-0 2-3-0 4-0-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 1-8 1-4 0-4

Players to Watch

USC

  • Tuli Tuipulotu has helped carry the Trojans’ defense with 25 tackles, 12.0 TFL, and nine sacks in nine games.
  • Shane Lee has played nine games, registering one interception to go along with 52 tackles, 5.0 TFL, 2.5 sacks, and one pass defended for the Trojans.
  • Eric Gentry has helped carry the Trojans’ defense with one interception to go along with 48 tackles, 1.0 TFL, one sack, and one pass defended in nine games.
  • An important contributor to the Trojans’ defense, Max Williams has two interceptions to go with 48 tackles, 1.0 TFL, and two passes defended in nine games.

Buffaloes

  • Josh Chandler-Semedo has collected 69 tackles, 10.0 TFL, and four sacks in nine games for the Buffaloes.
  • In nine games for the Buffaloes, Trevor Woods has amassed one interception to go with 73 tackles, 1.0 TFL, and one pass defended.
  • Quinn Perry has compiled 1.0 TFL and 50 tackles in nine games for the Buffaloes.
  • With 24 tackles, 6.0 TFL, and one sack in nine games, Terrance Lang has been making a big difference on defense for the Buffaloes.

USC vs. Colorado Predictions and Pick

USC vs. Colorado betting card

    Pick ATS:

    Trojans (-34)

    Pick OU:

    Under (65.5)

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How to Bet on USC vs. Colorado

You can bet on USC vs. Colorado at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s USC vs. Colorado picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is USC, and we project that USC will cover the spread (USC -34). Finally, we see the scoring in this one going under the posted total of 65.5 points.

WRITTEN BY

Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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