Oregon vs. BYU Prediction: Picks & Start Time – September 17

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The No. 25 Oregon Ducks (1-1) will clash with the No. 12 BYU Cougars (2-0) at Autzen Stadium in Eugene, Oregon.

Oregon vs. BYU Odds

Point Spread

The spread for this matchup is set at 3.5 points, with sportsbooks listing Oregon as the favorites.


As for the moneyline, Oregon has -169 odds to pick up the win, while BYU is listed at +140 to claim victory.


Finally, the total for the game is set at 58 points.


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Game Info

How to Watch Oregon vs. BYU Live?

  • Game Day: Saturday, September 17, 2022
  • Game Time: 3:30 PM ET
  • TV Channel: FOX
  • Location: Eugene, Oregon
  • Stadium: Autzen Stadium

Betting Preview


  • Last year, Oregon scored 6.6 more points per game (31.4) than BYU surrendered (24.8).
  • When the Ducks put up over 24.8 points last season, they were 5-4 against the spread and 9-0 overall.
  • Oregon racked up 34.8 more yards per game (423.6) than BYU allowed per contest (388.8) last year.
  • When the Ducks picked up more than 388.8 yards last year, the team was 5-5 against the spread and 9-1 overall.
  • Oregon rushed for 201.7 yards per game last season, 44.8 more than the 156.9 BYU allowed per contest.
  • The Ducks had a 4-6 ATS record and a 9-1 overall record when the team rushed for more than 156.9 yards last year.


  • BYU racked up 33.1 points per game last year, 6.1 more than Oregon allowed (27.0).
  • The Cougars were 3-3 against the spread and 6-0 overall last year when the team recorded over 27.0 points.
  • BYU racked up 451.8 yards per game last season, 67.7 more yards than the 384.1 Oregon gave up per contest.
  • In games that the Cougars totaled over 384.1 yards last season, the team was 3-6 against the spread and 7-2 overall.
  • Last year BYU ran for 44.9 more yards per game (187.7) than Oregon allowed per outing (142.8).
  • The Cougars had a 5-4 ATS record and a 9-0 overall record when the team rushed for more than 142.8 yards last season.

Oregon vs. BYU Betting Analysis

Oregon Betting Insights

  • Oregon was 5-9-0 against the spread last season.
  • As 3.5-point or greater favorites last season, Oregon went 3-6.
  • The Ducks finished with a 7-1 record in games they were listed as the moneyline favorite last season (winning 87.5% of those games).
  • The Ducks had a record of 6-1 when they played as a moneyline favorite with odds of -169 or shorter (87.5%).
  • Out of 14 Oregon games last season, seven hit the over.

Cougars Betting Insights

  • BYU beat the spread five times in 13 games last season.
  • As a 3.5-point underdog or greater, BYU had one win ATS (1-1) last year.
  • Last season, the Cougars were the underdog three times and won two of those games.
  • The Cougars entered three games last season as the underdog by +140 or more and were 0-0 in those contests.
  • There were six BYU games (out of 13) that hit the over last season.

Oregon vs. BYU Against The Spread & Betting Records


Overall Home Away
Point Total AVG 57.9 56.8 59.0
Implied Total AVG 35.9 38.9 33.0
ATS Record 5-9-0 2-5-0 3-4-0
Over/Under Record 7-7-0 5-2-0 2-5-0
Moneyline Favorite Record 7-1 6-0 1-1
Moneyline Underdog Record 2-3 0-0 2-3


Overall Home Away
Point Total AVG 56.8 55.4 58.4
Implied Total AVG 34.3 34.1 34.5
ATS Record 5-8-0 4-3-0 1-5-0
Over/Under Record 6-7-0 4-3-0 2-4-0
Moneyline Favorite Record 7-2 2-2 5-0
Moneyline Underdog Record 2-1 2-0 0-1

Last Season’s Leaders


  • As a tone-setter on defense, Noah Sewell recorded 99 tackles, 8.0 TFL, four sacks, and one interception in 14 games last year.
  • Verone McKinley III delivered 70 tackles, 2.0 TFL, and six interceptions in 14 games.
  • Kayvon Thibodeaux registered 7.0 sacks to go with 9.0 TFL and 48 tackles in 14 games played a season ago.
  • Mykael Wright amassed 1.0 TFL, 58 tackles, and one interception in 14 games.


  • Ben Bywater hit the gridiron for 13 games, totaling 1.0 sack to go with 8.0 TFL and 98 tackles.
  • Max Tooley accumulated 1.0 sack to go along with 4.0 TFL, 61 tackles, and one interception in 13 games.
  • Payton Wilgar helped on defense with two interceptions to go along with 50 tackles, 3.0 TFL, 1.5 sacks, and two passes defended in 13 games.
  • A big player on defense, Tyler Batty had 39 tackles, 4.0 TFL, and 3.5 sacks.

Oregon vs. BYU Predictions and Pick

Oregon vs. BYU betting card

    Pick ATS:

    Cougars (+3.5)

    Pick OU:

    Under (58)

How to Bet on Oregon vs. BYU

You can bet on Oregon vs. BYU at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Oregon vs. BYU picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is Oregon, and we predict that BYU will cover the spread (Oregon -3.5). Finally, we see the scoring in this one going under the posted total of 58 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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