The LSU Tigers (5-2) and No. 7 Ole Miss Rebels (7-0) will face each other in clash of SEC opponents at Tiger Stadium in Baton Rouge, Louisiana.
LSU vs. Ole Miss Odds
Point Spread
The spread for this matchup is set at 1.5 points, with oddsmakers listing LSU as the favorites.
Moneyline
As for the moneyline, LSU has -121 odds to pick up the win, while Ole Miss is listed at -103 to claim victory.
Over/Under
Finally, the total for the game is set at 64.5 points.

Game Info
How to Watch LSU vs. Ole Miss Live?
- Game Day: Saturday, October 22, 2022
- Game Time: 3:30 PM ET
- TV Channel: CBS
- Location: Baton Rouge, Louisiana
- Stadium: Tiger Stadium
Betting Preview
LSU
From an offensive standpoint, LSU ranks 36th in the FBS with 442.9 yards per game. Meanwhile, its defense ranks 29th in total defense (338.0 yards allowed per contest). From an offensive standpoint, LSU ranks 41st in the FBS with 33.7 points per game. Meanwhile, the team’s defense ranks 32nd in points allowed (338.0 points allowed per contest). LSU ranks 42nd in passing yards this year (269.6 per game), but has been thriving on defense, ranking 25th-best in the FBS with 191.9 passing yards allowed per game. LSU is averaging 173.3 rushing yards per game on offense this season (50th in the FBS), and is allowing 146.1 rushing yards per game (70th) on the other side of the ball. LSU sports the 75th-ranked defense this year in terms of third-down efficiency (39.4% third-down percentage allowed), and has been more effective on offense, ranking 23rd-best with a 48.4% third-down conversion rate. LSU has forced 12 total turnovers (28th in the FBS) this season and have turned it over 10 times (72nd in the FBS) for +2a turnover margin of +2, 43rd-ranked in college football.
Ole Miss
Ole Miss’ offense has been paving the way for the team, as it ranks 14th-best in the FBS with 502.9 total yards per contest. In terms of defense, it is giving up 346.0 total yards per game, which ranks 36th. Ole Miss has excelled on both offense and defense this season, ranking 15th-best in points per game (40.9) and 16th-best in points allowed per game (17.3). Ole Miss ranks 77th in the FBS with 231.4 passing yards per contest on offense, and it ranks 35th with 202.0 passing yards given up per game on defense. Ole Miss’ rushing attack has been paving the way for the team, as it ranks third-best in the FBS with 271.4 rushing yards per game. In terms of defense, it is ceding 144.0 rushing yards per game, which ranks 68th. Ole Miss’ third-down defense ranks 44th in the FBS with a 34.5% third-down conversion percentage surrendered, but it has been carried by its offense, which ranks third-best by putting up a 55.2% third-down rate. At +3, Ole Miss owns the 34th-ranked turnover margin in the FBS, with 13 forced turnovers (14th in the FBS) and 10 turnovers committed (72nd in the FBS).
LSU vs. Ole Miss Betting Analysis
LSU Betting Insights
LSU has covered the spread three times this season (3-2-0). In games it has played as 1.5-point favorites or more, LSU has an ATS record of 1-1. LSU games have gone over the total once this season. The Tigers have been listed as the moneyline favorite just two other times so far this season, and they won both of the games. The Tigers have played as a moneyline favorite of -121 or shorter in just two games this season, and they won both.
Rebels Betting Insights
Ole Miss has put together a record of 3-4-0 against the spread this year. Games involving Ole Miss have hit the over on three occasions this season. This is the first time the Rebels will play as underdogs this season. The Rebels have not been a bigger underdog this season than the -103 moneyline set for this game.

LSU vs. Ole Miss Against The Spread & Betting Records
LSU
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 51.6 | 53.8 | 48.3 |
Implied Total AVG | 30.6 | 33.0 | 27.0 |
ATS Record | 3-2-0 | 2-1-0 | 1-1-0 |
Over/Under Record | 1-4-0 | 0-3-0 | 1-1-0 |
Moneyline Favorite Record | 2-0 | 1-0 | 1-0 |
Moneyline Underdog Record | 2-1 | 1-1 | 1-0 |
Rebels
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 59.3 | 58.6 | 61.0 |
Implied Total AVG | 39.3 | 39.4 | 39.0 |
ATS Record | 3-4-0 | 1-4-0 | 2-0-0 |
Over/Under Record | 3-4-0 | 2-3-0 | 1-1-0 |
Moneyline Favorite Record | 7-0 | 5-0 | 2-0 |
Moneyline Underdog Record | 0-0 | 0-0 | 0-0 |
Players to Watch
LSU
- As part of the Tigers’ defense, BJ Ojulari has compiled 21 tackles, 3.0 TFL, and 4.5 sacks in seven games.
- The Tigers’ defense has been helped by Micah Baskerville, who has played seven games and amassed 1.0 sack to go with 3.0 TFL, 36 tackles, and one interception.
- The Tigers’ defensive unit has been helped by Jay Ward, who has played seven games and totaled one interception to go along with 30 tackles, 1.0 TFL, and one pass defended.
- With 1.0 sack to go along with 1.0 TFL, 24 tackles, and one interception, Greg Brooks Jr. has helped spur the Tigers’ defense over seven games.
Rebels
- As a tone-setter on defense, the Rebels’ A.J. Finley has compiled 49 tackles and two interceptions in seven games.
- Troy Brown has been doing his part on defense, amassing 49 tackles, 1.0 TFL, and 0.5 sacks for the Rebels.
- Otis Reese has been doing his part on defense, amassing 2.0 sacks to go with 4.0 TFL and 34 tackles for the Rebels.
- Ladarius Tennison has compiled 1.0 sack to go with 5.0 TFL and 26 tackles in seven games for the Rebels.
LSU vs. Ole Miss Predictions and Pick
LSU vs. Ole Miss betting card
- Pick ATS:
Rebels (+1.5)
Pick OU:
Under (64.5)

How to Bet on LSU vs. Ole Miss
You can bet on LSU vs. Ole Miss at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.
And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s LSU vs. Ole Miss picks, don’t forget to check out our free parlay calculator.
Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.
Our prediction to win this game is Ole Miss, and we predict that Ole Miss will cover the spread (LSU -1.5). Finally, we see the scoring in this one going under the posted total of 64.5 points.