Kansas vs. Duke Prediction: Picks & Start Time – September 2022

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The Kansas Jayhawks (3-0) and Duke Blue Devils (3-0) will meet in a matchup at David Booth Memorial Stadium (Lawrence, KS) in Lawrence, Kansas.

Kansas vs. Duke Odds

Point Spread

The spread for this matchup is set at 7 points, with bookmakers listing Kansas as the favorites.


As for the moneyline, Kansas has -296 odds to pick up the win, while Duke is listed at +231 to claim victory.


Finally, the total for the game is set at 63.5 points.

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Game Info

How to Watch Kansas vs. Duke Live?

  • Game Day: Saturday, September 24, 2022
  • Game Time: 12:00 PM ET
  • TV Channel: Fox Sports 1
  • Location: Lawrence, Kansas
  • Stadium: David Booth Memorial Stadium (Lawrence, KS)

Betting Preview


Kansas is totaling 453.0 yards per game on offense (49th in the FBS), and rank 83rd on the other side of the ball, yielding 379.0 yards allowed per game. Kansas ranks 83rd in scoring defense this year (27.3 points allowed per game), but has been shining on offense, ranking third-best in the FBS with 53.0 points per game. Kansas is compiling 194.0 passing yards per game on offense (102nd in the FBS), and ranks 85th defensively with 241.3 passing yards allowed per game. Kansas has the 66th-ranked defense this year in terms of rushing yards (137.7 rushing yards allowed per game), and has been better on the other side of the ball, ranking seventh-best with 259.0 rushing yards per game. On offense, Kansas has been a top-25 unit in terms of third-down efficiency, ranking second-best in the FBS by putting up a 68.6% third-down percentage. The defense ranks 100th on defense (42.2% third-down conversion rate allowed). Kansas ranks 35th in college football with a +2 turnover margin after forcing 5 turnovers (48th in the FBS) while committing three (33rd in the FBS).


Duke is generating 460.3 total yards per contest on offense this season (44th-ranked). Meanwhile, it is giving up 348.0 total yards per game (56th-ranked). Duke’s defense has been paving the way for the team, as it ranks 23rd-best in the FBS with 14.3 points allowed per game. In terms of offense, it is accumulating 36.7 points per game, which ranks 46th. With 255.3 passing yards per game on offense, Duke ranks 56th in the FBS. Defensively, it ranks 78th, surrendering 228.7 passing yards per contest. From an offensive standpoint, Duke is putting up 205.0 rushing yards per game (37th-ranked). It ranks 51st in the FBS on defense (119.3 rushing yards given up per game). Duke is putting up a 42.9% third-down conversion percentage on offense this season (54th-ranked). Meanwhile, it is giving up a 40.0% third-down rate (89th-ranked) on defense. Duke has accumulated seven forced turnovers this season and have turned it over two times, leading to a +5 turnover margin, which ranks 10th-best in the FBS.

Kansas vs. Duke Betting Analysis

Kansas Betting Insights

Kansas has covered (or pushed) in every game with a spread this season to compile a 3-0-0 ATS record. Kansas has a perfect 1-0 ATS record when playing as at least 7-point favorites. Every game involving Kansas has hit the over so far this season. The Jayhawks are the moneyline favorite in their first game this season. The Jayhawks have never played a game this season with moneyline odds of -296 or shorter.

Blue Devils Betting Insights

Duke has covered the spread two times this season (2-1-0). Duke is a perfect 1-0 ATS when playing as at least 7-point underdogs. This year, Duke games have hit the over just once. The Blue Devils won the only game they’ve played as the underdog this season. The Blue Devils have entered two games this season as the underdog by +231 or more and won each of those games.

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Kansas vs. Duke Against The Spread & Betting Records


Overall Home Away
Point Total AVG 59.8 62.0 58.8
Implied Total AVG 39.0 47.0 35.0
ATS Record 3-0-0 1-0-0 2-0-0
Over/Under Record 3-0-0 1-0-0 2-0-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 2-0 0-0 2-0

Blue Devils

Overall Home Away
Point Total AVG 54.2 52.8 57.0
Implied Total AVG 36.0 37.0 34.0
ATS Record 2-1-0 1-1-0 1-0-0
Over/Under Record 1-2-0 1-1-0 0-1-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 1-0 0-0 1-0

Players to Watch


  • Lonnie Phelps has suited up for three games, collecting 3.0 sacks to go with 5.0 TFL and 13 tackles for the Jayhawks.
  • Craig Young has played three games, posting 16 tackles, 2.0 TFL, and one sack for the Jayhawks.
  • The Jayhawks’ defense has been helped by Kenny Logan Jr., who has played three games and compiled one interception to go along with 17 tackles and one pass defended.
  • With 1.0 TFL and 19 tackles, Rich Miller has helped carry the Jayhawks’ defense over three games.

Blue Devils

  • Brandon Johnson has been causing chaos on defense, totaling one interception to go with three tackles, one sack, and one pass defended for the Blue Devils.
  • The Blue Devils’ DeWayne Carter has totaled 1.5 sacks to go with 1.0 TFL and three tackles in three games.
  • The Blue Devils’ Ja’Mion Franklin has recorded three tackles, 1.0 TFL, and 1.5 sacks in three games.
  • With five tackles, 1.0 TFL, and one sack in three games, Jaylen Stinson has been doing his part on defense for the Blue Devils.

Kansas vs. Duke Predictions and Pick

Kansas vs. Duke betting card

    Pick ATS:

    Jayhawks (-7)

    Pick OU:

    Over (63.5)

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How to Bet on Kansas vs. Duke

You can bet on Kansas vs. Duke at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Kansas vs. Duke picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this game is Kansas, and we project that Kansas will cover the spread (Kansas -7). Finally, we see the scoring in this one going over the posted total of 63.5 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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