Iowa State vs. Baylor Prediction: Picks & Start Time – September 2022

httpscdn.dataskrive.comapiassetkEjsMZ7iowa state cyclones vs baylor bears Betsperts Media & Technology

Big 12 foes will clash when the Iowa State Cyclones (3-0) meet the No. 17 Baylor Bears (2-1).

Iowa State vs. Baylor Odds

Point Spread

The spread for this matchup is set at 2.5 points, with bookmakers listing Iowa State as the favorites.


As for the moneyline, Iowa State has -145 odds to pick up the win, while Baylor is listed at +116 to claim victory.


Finally, the total for the game is set at 45 points.

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Game Info

How to Watch Iowa State vs. Baylor Live?

  • Game Day: Saturday, September 24, 2022
  • Game Time: 12:00 PM ET
  • TV Channel: ESPN2
  • Location: Ames, Iowa
  • Stadium: Jack Trice Stadium

Betting Preview

Iowa State

Iowa State sports the 70th-ranked offense this year (415.0 yards per game), and has been even more effective defensively, ranking ninth-best with just 234.3 yards allowed per game. Iowa State ranks 74th in points scored this season (31.7 points per game), but has been thriving on defense, ranking 12th-best in the FBS with 9.0 points allowed per game. Iowa State is putting up 259.0 passing yards per game on offense, which ranks them 48th in the FBS. The defense ranks 26th, giving up 174.3 passing yards per contest. On the defensive side of the ball, Iowa State has been a top-25 unit in terms of rushing yards, ranking fourth-best by surrendering only 60.0 per game. The Cyclones rank 77th on offense (156.0 rushing yards per game). Iowa State has been shining on both sides of the ball in terms of third-down efficiency, ranking 24th-best in third-down percentage (51.1%) and 17th-best in third-down percentage allowed (25.6%). Iowa State has forced eight total turnovers (10th in the FBS) this season and have turned it over five times (72nd in the FBS) for a turnover margin of +3, the 22nd-best in college football.


Baylor ranks 47th with 454.3 total yards per contest on offense, and it ranks 26th with 290.3 total yards given up per contest on the defensive side of the ball. Baylor has been top-25 on both sides of the ball this season, as it ranks 15th-best in points per game (43.7) and 23rd-best in points surrendered per game (14.3). From an offensive perspective, Baylor is generating 219.7 passing yards per game (92nd-ranked). It ranks 60th in the FBS on defense (206.3 passing yards given up per game). In terms of rushing, Baylor has excelled on both sides of the ball this season, ranking 16th-best in rushing yards per game (234.7) and 22nd-best in rushing yards allowed per game (84.0). Baylor ranks 26th in the FBS with a 50.0% third-down conversion rate, but it has been lifted up by its defense, which ranks 23rd-best by allowing a 26.7% third-down rate. With two forced turnovers (111th in the FBS) and three turnovers committed (33rd in the FBS) this season, Baylor ranks 100th in the FBS with a turnover margin of -1.

Iowa State vs. Baylor Betting Analysis

Iowa State Betting Insights

Iowa State has covered the spread in a matchup two times this season (2-1-0). Iowa State has 1-1 ATS when playing as at least 2.5-point favorites. This season, Iowa State games have hit the over once. The Cyclones have been listed as the moneyline favorite just one other time so far this season, a game they won. The Cyclones have played as a moneyline favorite of -145 or shorter in just one game this season, which they won.

Bears Betting Insights

Baylor has covered the spread two times in three games with a set number. Baylor is winless against the spread when it has played as 2.5-point underdogs or more (0-1). Baylor games have gone over the total once this season. The Bears lost the only game they’ve played as the underdog this season. The Bears have played as an underdog of +116 or more once this season and won that game.

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Iowa State vs. Baylor Against The Spread & Betting Records

Iowa State

Overall Home Away
Point Total AVG 46.8 51.0 38.5
Implied Total AVG 32.7 38.5 21.0
ATS Record 2-1-0 1-1-0 1-0-0
Over/Under Record 1-2-0 1-1-0 0-1-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 1-0 0-0 1-0


Overall Home Away
Point Total AVG 51.5 50.0 54.5
Implied Total AVG 38.3 43.0 29.0
ATS Record 2-1-0 2-0-0 0-1-0
Over/Under Record 1-2-0 1-1-0 0-1-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 0-1 0-0 0-1

Players to Watch

Iowa State

  • O’Rien Vance has played three games, registering 1.0 sack to go with 1.0 TFL and nine tackles for the Cyclones.
  • The Cyclones’ defense has been helped by Colby Reeder, who has suited up for three games and amassed 1.0 TFL, five tackles, and two interceptions.
  • Gerry Vaughn has helped spur the Cyclones’ defense with seven tackles and one sack in three games.
  • With 1.0 sack to go along with 1.0 TFL and three tackles, Will McDonald IV has helped propel the Cyclones’ defense over three games.


  • As a tone-setter on defense, the Bears’ Matt Jones has registered four tackles, 1.0 TFL, and 1.5 sacks in three games.
  • The Bears’ Bryson Jackson has compiled 1.0 TFL in three games.
  • Devin Neal has 1.0 sack to go with 1.0 TFL and four tackles in three games.
  • With three tackles, 1.0 TFL, and one sack in three games, Brooks Miller has been doing his part on defense for the Bears.

Iowa State vs. Baylor Predictions and Pick

Iowa State vs. Baylor betting card

    Pick ATS:

    Cyclones (-2.5)

    Pick OU:

    Under (45)

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How to Bet on Iowa State vs. Baylor

You can bet on Iowa State vs. Baylor at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Iowa State vs. Baylor picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this matchup is Iowa State, and we predict that Iowa State will cover the spread (Iowa State -2.5). Finally, we see the scoring in this one going under the posted total of 45 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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