Illinois vs Missouri Prediction: Odds, Picks, Best Bets – Thursday, December 22, 2022

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The Illinois Fighting Illini (8-3) play the Missouri Tigers (10-1) at 9:00 PM ET on Thursday, December 22, 2022.

Illinois is a healthy 6.5-point favorite against Missouri when the Fighting Illini take the court against the Tigers on Thursday. A 153.5-point over/under is set for the game.

Illinois vs. Missouri Odds

Point Spread for Illinois vs. Missouri

The spread for this matchup is set at 6.5 points, with oddsmakers listing Illinois as the favorite.

Illinois vs. Missouri Moneyline

As for the moneyline, Illinois has -277 odds to pick up the win, while Missouri is listed at +223 to claim victory.


Finally, the total for the game is set at 153.5 points.

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Game Time and How to Watch

  • Game Day: Thursday, December 22, 2022
  • Game Time: 9:00 PM ET
  • Location: St. Louis, Missouri
  • Arena: Enterprise Center

Illinois vs. Missouri Betting Trends

In the Illinois’ 11 games this season, it has six wins against the spread. The Fighting Illini have been favorites in six games this season and have come away with the win four times (66.7%) in those contests. Illinois’ games this year have hit the over 50% of the time (five out of 10 games with a set point total).

Missouri is 6-4-0 against the spread this year. The Tigers have been the moneyline underdog only two other times so far this season, and they split the games. Missouri’s games this year have hit the over on six of 10 set point totals (60%).

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Illinois vs. Missouri Key Players to Watch


Terrence Shannon Jr. posts a team-best 17.8 points per game. He is also posting 5.5 rebounds and 2.7 assists, shooting 45.5% from the field and 34.8% from downtown with 2.1 made 3-pointers per game. Coleman Hawkins leads his squad in both rebounds (6.1) and assists (4.2) per contest, and also puts up 9.5 points. Defensively, he delivers 1.2 steals and 1.5 blocked shots. Matthew Mayer averages 9.2 points, 4.4 rebounds and 1.2 assists per contest, shooting 44.6% from the field and 35.4% from beyond the arc with 1.5 made 3-pointers per game. Dain Dainja puts up 9.8 points, 5.4 rebounds and 0.4 assists per game. Defensively, he delivers 0.8 steals and 1.0 block.


D’Moi Hodge is the Tigers’ top scorer (16.4 points per game) and assist man (2.5), and produces 4.2 rebounds. Kobe Brown is posting a team-best 5.7 rebounds per game. And he is producing 12.9 points and 2.3 assists, making 60.6% of his shots from the field. Nick Honor is putting up a team-leading 3.1 assists per game. And he is producing 11.1 points and 2.0 rebounds, making 51.3% of his shots from the floor and 47.2% from beyond the arc, with 2.3 triples per contest. Noah Carter is putting up 11.6 points, 5.0 rebounds and 1.7 assists per game, making 52.3% of his shots from the floor and 37.2% from 3-point range, with 1.5 treys per contest.

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What you need to know about the Illinois Fighting Illini

On offense, the Fighting Illini are scoring 78.1 points per game (76th-ranked in college basketball). They are giving up 62.1 points per contest on defense (43rd-ranked). With 36.6 boards per game, Illinois is 40th in the country. It cedes 29.5 rebounds per contest, which ranks 96th in college basketball.

Illinois is making 9.4 three-pointers per game (35th-ranked in college basketball) this season, while putting up a 34.4% three-point percentage (149th-ranked). The Fighting Illini are surrendering 6.1 three-pointers per game (69th-ranked in college basketball) this season, while allowing a 31.6% three-point percentage (127th-ranked).

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What you need to know about the Missouri Tigers

In 2022-23, the Tigers are fourth-best in the country on offense (88.4 points scored per game) and ranked 317th on defense (75.0 points allowed). In 2022-23, Missouri is 245th in college basketball in rebounds (31.4 per game) and 212th in rebounds conceded (31.4).

In 2022-23 Missouri is 18th-best in college basketball in 3-point makes (10.0 per game), and it ranks No. 88 in 3-point percentage (36.1%). The Tigers are the 13th-worst team in college basketball in 3-pointers allowed (9.5 per game) and 16th-worst in 3-point percentage defensively (37.6%).

Illinois vs. Missouri Prediction & Pick

Our prediction to win this game is Illinois, and we predict that Missouri will cover the spread (Illinois -6.5). Finally, we see the scoring in this one going under the posted total of 153.5 points.

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How to bet Illinois vs. Missouri

You can bet on Illinois vs. Missouri at every legal online sportsbook. For more college basketball odds, including moneylines, spreads, over/under totals, check out the latest NCAA lines as well as our guide to the best college basketball betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Illinois vs. Missouri picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college basketball? Check out our complete guide to sports betting.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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