White Sox vs Guardians Prediction: Picks, Live Odds & Start Time – September 20, 2022

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A pair of teams in the AL Central — the Cleveland Guardians (80-67) and the Chicago White Sox (76-71) — clash on Tuesday at 8:10 PM ET, at Guaranteed Rate Field. The White Sox will hand the ball to Dylan Cease (14-7), and the Guardians will counter with Aaron Civale (2-6).

The White Sox are moderate favorites on the moneyline (-174) at home over the Guardians (+147). The contest has an over/under set at 7.5.

White Sox vs. Guardians Odds

Run Line

Chicago White Sox (-1.5)

Moneyline

White Sox (-174)

Total

7.5 Runs (Over: +103, Under: -123)

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When, Where, at What Time is White Sox vs. Guardians

  • Game Day: Tuesday, September 20, 2022
  • Game Time: 8:10 PM ET
  • Location: Chicago, Illinois
  • Stadium: Guaranteed Rate Field

White Sox Injury Report

Name Status Injury
Tim Anderson 10 Day Injury List Hand
Michael Kopech 15 Day Injury List Shoulder
Danny Mendick 60 Day Injury List Knee
Kyle Crick 60 Day Injury List Elbow
Garrett Crochet 60 Day Injury List Elbow
Jonathan Stiever 60 Day Injury List Back
Luis Robert Day-to-day Hand / Wrist
Joe Kelly Bereavement List Personal

Guardians Injury Report

Name Status Injury
Aaron Civale 15 Day Injury List Arm
Zach Plesac 15 Day Injury List Hand
Anthony Gose 60 Day Injury List Tricep

Last Time Out: White Sox and Guardians

The White Sox defeated the Tigers by an 11-5 score in their most recent game Tuesday. Eloy Jimenez went 3-for-4 with a double, a home run and three RBI to lead them offensively while Tanner Banks picked up the win after throwing three innings, giving up one earned run on one hit while striking out five.

The Guardians beat the Twins 11-4 yesterday. Amed Rosario led the way offensively after going 1-for-3 with a home run and three RBI, and Cal Quantrill got the win, throwing five innings, giving up three earned runs on nine hits while striking out two.

Betting Trends

White Sox Betting Records and Team Stats

This season, the White Sox have won 55 out of the 101 games, or 54.5%, in which they’ve been favored. Chicago has entered 32 games this season favored by -174 or more and is 21-11 in those contests. The moneyline for this contest implies a 63.5% chance of a victory for the White Sox. Chicago and its opponents have gone over the total this season in 66 of their 151 opportunities. The White Sox are 70-81-0 against the spread this season.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
José Abreu 145 .309 (7) .383 (7) .452 (46) 2.4% (93) 16.5% (37) 9.5% (51)
Andrew Vaughn 122 .287 (23) .338 (51) .457 (42) 3.3% (60) 15.8% (31) 5.7% (116)
Elvis Andrus 134 .258 (68) .316 (89) .413 (81) 2.7% (82) 15.6% (29) 7.4% (83)
Luis Robert 96 .288 (-) .323 (-) .432 (-) 3.0% (-) 18.9% (-) 4.3% (-)
A.J. Pollock 125 .242 (94) .289 (123) .381 (111) 2.5% (90) 19.2% (64) 6.1% (112)

Guardians Betting Records and Team Stats

The Guardians have been chosen as underdogs in 75 games this year and have walked away with the win 32 times (42.7%) in those games. This season, Cleveland has come away with a win six times in 18 chances when named as an underdog of at least +147 or longer on the moneyline. The moneyline set for this matchup implies the Guardians have a 40.5% chance of walking away with the win. Contests with Cleveland have gone over the total set by sportsbooks in 68 of 151 chances this season. In 151 games with a line this season, the Guardians have a mark of 77-74-0 against the spread.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
José Ramírez 143 .278 (33) .357 (28) .524 (10) 4.5% (28) 11.5% (7) 10.3% (37)
Steven Kwan 133 .291 (19) .370 (15) .383 (110) 0.7% (129) 9.3% (2) 10.4% (36)
Amed Rosario 140 .282 (27) .313 (93) .405 (88) 1.8% (112) 16.8% (39) 3.9% (132)
Andrés Giménez 134 .297 (12) .368 (16) .470 (30) 3.2% (64) 19.4% (68) 6.2% (108)
Josh Naylor 114 .256 (-) .314 (-) .447 (-) 4.0% (-) 15.6% (-) 6.9% (-)

White Sox vs. Guardians Picks and Predictions

We pick that the White Sox will pick up the victory in this contest, and they’re our choice on the moneyline (-174). If you’re looking for a pick on the over/under, we see the final scoring winding up over the total (7.5 runs).

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Why claim this offer
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WRITTEN BY

Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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