Astros vs Yankees Odds, Picks & Predictions – July 21

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On Thursday, a series opener is on the schedule, with the New York Yankees (64-28) visiting the Houston Astros (59-32) at 1:10 PM ET. The Astros will hand the ball to Cristian Javier (6-5), but the Yankees’ starter has not been announced yet.

At home, the Astros are favored to win on the moneyline (-125) over the Yankees (+104). The contest has a total set at 8.

Astros vs. Yankees Odds

Run Line

Houston Astros (-1.5)


Astros (-125)


8 Runs (Over: -112, Under: -109)

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When, Where, at What Time is Astros vs. Yankees

  • Game Day: Thursday, July 21, 2022
  • Game Time: 1:10 PM ET
  • Location: Houston, Texas
  • Stadium: Minute Maid Park

Astros Injury Report

Jason Castro10 Day Injury ListKnee
Yordan Alvarez10 Day Injury ListHand
Michael Brantley10 Day Injury ListShoulder
Parker Mushinski15 Day Injury ListElbow
Lance McCullers Jr.60 Day Injury ListForearm
Josh James60 Day Injury ListBack
Blake Taylor60 Day Injury ListElbow

Yankees Injury Report

Luis Severino15 Day Injury ListShoulder
Miguel Castro15 Day Injury ListShoulder
Ron Marinaccio15 Day Injury ListShoulder
Chad Green60 Day Injury ListElbow
Domingo Germán60 Day Injury ListShoulder
Zack Britton60 Day Injury ListElbow
Ben Rortvedt60 Day Injury ListOblique
Stephen Ridings60 Day Injury ListShoulder

Last Time Out: Astros and Yankees

The Astros lost 4-3 to the Athletics Thursday, with Rafael Montero (two innings, giving up one earned run on two hits while striking out one) on the hook for the loss. Jeremy Pena went 2-for-4 with a home run and two RBI to lead the Astros offensively in the defeat.

The Yankees secured a 13-2 victory over the Red Sox Thursday. Tim Locastro (3-for-5 with a home run and two RBI) led the way offensively, while Gerrit Cole got the win on the mound after going seven innings, giving up two earned runs on four hits while striking out 12.

Betting Trends

Astros Betting Records and Team Stats

The Astros have entered the game as favorites 75 times this season and won 52, or 69.3%, of those games. Houston has a record of 45-20, a 69.2% win rate, when favored by -125 or more by oddsmakers this season. The bookmakers’ moneyline implies a 55.6% chance of a victory for the Astros. Games involving Houston have gone over the total set by oddsmakers in 32 of 91 chances this season. The Astros are 47-44-0 against the spread this season.

NameGPAVG (Rank)OBP (Rank)SLG (Rank)HR% (Rank)K% (Rank)BB% (Rank)
Kyle Tucker85.252 (81).344 (52).475 (38)5.2% (18)16.2% (41)12.4% (15)
Alex Bregman88.238 (112).357 (33).408 (90)2.9% (83)13.1% (14)14.1% (6)
Jose Altuve74.275 (44).368 (19).518 (14)5.3% (16)15.8% (36)11.1% (38)
Yuli Gurriel83.238 (112).289 (137).391 (109)2.2% (107)13.2% (15)5.8% (132)
Jeremy Pena71.263 (64).310 (107).454 (50)4.6% (29)24.3% (112)4.9% (146)

Yankees Betting Records and Team Stats

The Yankees have won in four of the five contests they have been named as odds-on underdogs in this year. New York has a win-loss record of 4-1 when favored by +104 or worse by oddsmakers this year. Oddsmakers have implied with the moneyline set for this matchup that the Yankees have a 49% chance of pulling out a win. New York’s games have gone over the total in 45 of their 92 opportunities. The Yankees are 45-47-0 against the spread in their 92 games that had a posted line this season.

NameGPAVG (Rank)OBP (Rank)SLG (Rank)HR% (Rank)K% (Rank)BB% (Rank)
Aaron Judge89.284 (34).364 (25).618 (2)8.5% (1)25.8% (129)11.4% (33)
Anthony Rizzo86.221 (133).341 (57).495 (21)6.1% (9)17.7% (55)11.9% (21)
DJ LeMahieu84.279 (36).383 (12).403 (94)2.2% (107)12.6% (12)13.4% (9)
Giancarlo Stanton76.237 (115).319 (94).516 (16)7.6% (3)27.1% (136)11.0% (40)
Gleyber Torres82.268 (56).325 (82).484 (27)4.5% (31)19.1% (69)7.3% (98)

Astros vs. Yankees Picks and Predictions

We pick that the Yankees will pick up the victory in this contest, and they’re our choice on the moneyline (+104). If you’re looking for a pick on the over/under, we predict the final scoring winding up over the total (8 runs).

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Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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