Buccaneers vs Cowboys Prediction: Week 1 Picks, Live Odds & Start Time – September 11, 2022

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On Sunday, September 11, 2022, the Dallas Cowboys (0-0) host the Tampa Bay Buccaneers (0-0) at AT&T Stadium.

Buccaneers vs. Cowboys Odds

Point Spread

The spread for this matchup is set at 2.5 points, with oddsmakers listing the Buccaneers as the favorites.


As for the moneyline, the Buccaneers have -140 odds to pick up the win, while the Cowboys are listed at +120 to claim victory.


Finally, the total for the game is set at 50 points.

Game Info

How to Watch Buccaneers vs. Cowboys Live?

  • Game Day: Sunday, September 11, 2022
  • Game Time: 8:20 PM ET
  • TV Channel: NBC
  • Location: Arlington, Texas
  • Stadium: AT&T Stadium

Betting Preview


  • The Buccaneers, on average, scored 9.0 more points (30.1) than the Cowboys allowed (21.1) last year.
  • When Tampa Bay scored over 21.1 points last season, it went 9-5 against the spread and 12-2 overall.
  • The Cowboys’ defense gave up 351.0 yards per game last year, 54.9 less than the 405.9-yard average from the Buccaneers’ offense. The Buccaneers gained 6.1 yards per play and the Cowboys allowed 5.5.
  • In games that Tampa Bay picked up more than 351.0 yards last year, the team was 8-6 against the spread and 12-2 overall.
  • The Cowboys’ defense gave up an average of 112.8 yards to opposing running games last season. That is 14.4 more yards than the Buccaneers averaged running the football (98.4).
  • When Tampa Bay rushed for over 112.8 yards last season, it compiled a 5-2 ATS record and a 6-1 overall record.


  • The Cowboys, on average, scored 10.4 more points (31.2) than the Buccaneers allowed (20.8) last year.
  • When Dallas put up over 20.8 points last season, it was 11-2 against the spread and 10-3 overall.
  • The Cowboys accumulated 407.0 yards per game last year, 75.5 more than the Buccaneers allowed (331.5). The Cowboys picked up 6.0 yards per play, while the Buccaneers gave up 5.2.
  • When Dallas totaled over 331.5 yards last year, the team was 11-1 against the spread and 10-2 overall.
  • The Buccaneers’ defense gave up an average of 92.5 yards to opposing running games last year. That is 32.1 less yards than the Cowboys averaged running the football (124.6).
  • Dallas had an 11-0 ATS record and an 11-0 overall record when the team rushed for over 92.5 yards last season.

Buccaneers vs. Cowboys Injury Report


Buccaneers: No Injuries Listed


Cowboys: No Injuries Listed

Buccaneers vs. Cowboys Betting Analysis

Buccaneers Betting Insights

  • The Buccaneers had nine wins in 17 games against the spread last season.
  • Against the spread, as 2.5-point favorites or more, the Buccaneers went 9-7 last season.
  • Tampa Bay finished with a 13-4 record in games it was favored on the moneyline last season (winning 76.5% of those games).
  • Tampa Bay finished 13-3 last year (winning 81.2% of its games) when it played as a moneyline favorite of -140 or shorter.
  • In 17 Buccaneers games last year, nine went over the total.

Cowboys Betting Insights

  • The Cowboys covered the spread 13 times in 17 games last year.
  • Against the spread, as underdogs of 2.5 points or greater, the Cowboys went 3-1 last season.
  • Dallas won two of the four games it played as underdogs last season.
  • Last season, Dallas won two of its three games when it was the underdog by at least +120 on the moneyline.
  • Last season, eight of the Cowboys’ 17 games went over the point total.

Buccaneers vs. Cowboys Against The Spread & Betting Records


Overall Home Away
Point Total AVG 49.6 49.1 50.0
Implied Total AVG 29.4 30.0 28.9
ATS Record 9-8-0 6-2-0 3-6-0
Over/Under Record 9-8-0 5-3-0 4-5-0
Moneyline Favorite Record 13-4 7-1 6-3
Moneyline Underdog Record 0-0 0-0 0-0


Overall Home Away
Point Total AVG 50.3 51.4 49.3
Implied Total AVG 28.5 29.4 27.8
ATS Record 13-4-0 5-3-0 8-1-0
Over/Under Record 8-9-0 5-3-0 3-6-0
Moneyline Favorite Record 10-3 5-3 5-0
Moneyline Underdog Record 2-2 0-0 2-2

Players to Watch


  • In 17 games played last year, Tom Brady amassed 5,316 passing yards (leading the league), with 43 touchdowns (first in the NFL) against 12 interceptions and completing 67.5% of his attempts.
  • Brady also rushed for two touchdowns and 81 yards.
  • Mike Evans put together a 2021 stat sheet that included 74 catches for 1,035 yards and 14 receiving touchdowns (second in the NFL) over 16 games played. He was on the receiving end of 114 targets and averaged 4.6 receptions per game.
  • Last season over 14 games, Leonard Fournette racked up 812 rushing yards and scored eight rushing touchdowns. He averaged 58.0 yards per game and 4.5 per attempt (25th in the NFL).
  • Fournette helped in the passing game, picking up 454 receiving yards (32.4 per game) on 69 catches (4.9 per game), while being targeted 84 times. He had two receiving touchdowns.
  • Chris Godwin had 98 catches for 1,103 yards and five receiving touchdowns. He averaged 7.0 yards per game over 14 games and was targeted 128 times.
  • Devin White’s 2021 output included 128 tackles, 8.0 TFL, and 3.5 sacks in 17 games.
  • Logan Ryan had 1.0 sack in addition to his 2.0 TFL and 117 tackles over 15 games with the Giants.
  • Shaquil Barrett recorded 9.5 sacks as well as 9.0 TFL, 50 tackles, and one interception in the 2021 season.
  • Antoine Winfield Jr. totaled 2.0 sacks as well as 4.0 TFL, 88 tackles, and two interceptions.


  • In 16 games last year, Dak Prescott threw for 4,449 yards (278.1 yards per game) while recording 37 touchdowns, 10 interceptions and a 68.8% completion percentage.
  • Prescott also provided value on the ground, rushing for 146 yards (3.0 YPC) and one touchdown.
  • Ezekiel Elliott generated 1,002 rushing yards (4.2 yards per carry) and 10 TDs.
  • The passing attack was also aided by the receiving ability of Elliott, who reeled in 47 balls (on 65 targets) for 287 yards and two touchdowns.
  • CeeDee Lamb was a key piece of the air attack last season, posting 79 catches for 1,102 yards and six touchdowns.
  • As a key contributor to the passing attack, Dalton Schultz produced 808 receiving yards and eight touchdowns on 78 receptions.
  • Micah Parsons helped spur the defense with 84 tackles, 20.0 TFL, and 13.0 sacks in 16 games.
  • With two interceptions to go with 102 tackles, 9.0 TFL, 1.0 sack, and 10 passes defended in 16 games, Jayron Kearse was a significant contributor on defense last season.
  • Trevon Diggs registered 11 interceptions to go along with 52 tackles and 21 passes defended in 16 games.
  • Anthony Brown amassed 1.0 TFL, 71 tackles, and three interceptions in 16 games.

Buccaneers vs. Cowboys Predictions and Pick

Our prediction to win this matchup is the Cowboys, and we expect that Cowboys will cover the spread (Buccaneers -2.5). Finally, we see the scoring in this one going over the posted total of 50 points.

How to Bet on Buccaneers vs. Cowboys

You can bet on Buccaneers vs. Cowboys at every legal online sportsbook. For more NFL odds, including moneylines, spreads, over/under totals as well as NFL prop odds, check out the latest NFL lines as well as our guide to the best NFL betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Buccaneers vs. Cowboys picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on football? Check out our complete guide to sports betting.


Andy Molitor

Andy has been involved in sports betting on and off his entire adult life and has been creating content surrounding it for the past five years. While the NFL is his first love, he also bets hundreds of college basketball games every winter and loves sweating golf DFS during the football offseason.

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