Chiefs vs. Jaguars Prediction: Week 10 Odds, Picks & Moneyline – November 2022

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Sunday, November 13, 2022 will see the Kansas City Chiefs (6-2) challenge the Jacksonville Jaguars (3-6) at Arrowhead Stadium.

Chiefs vs. Jaguars Odds

Point Spread

The spread for this matchup is set at 9 points, with oddsmakers listing the Chiefs as the favorites.


As for the moneyline, the Chiefs have -410 odds to pick up the win, while the Jaguars are listed at +330 to claim victory.


Finally, the over/under for the game is set at 51 points.


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Game Info

How to Watch Chiefs vs. Jaguars Live?

  • Game Day: Sunday, November 13, 2022
  • Game Time: 1:00 PM ET
  • TV Channel: CBS
  • Location: Kansas City, Missouri
  • Stadium: Arrowhead Stadium

Betting Preview


On offense, the Chiefs have been a top-five unit, ranking second-best in the NFL by putting up 415.3 yards per game. They rank 20th on defense (351.5 yards allowed per game). On offense, the Chiefs have been a top-five unit, ranking best in the NFL by averaging 30.4 points per game. They rank 20th on defense (23.6 points allowed per game).

On offense, the Chiefs have been a top-five unit in terms of passing yards, ranking best in the NFL by compiling 311.8 per game. They rank 24th on defense (249.5 passing yards allowed per game). The Chiefs rank 23rd in rushing yards this year (103.5 rushing yards per game), but they’ve been playing really well on the other side of the ball, ranking fifth-best in the NFL with 102.0 rushing yards allowed per game.

Offensively, the Chiefs have been a top-five unit in terms of third-down efficiency, ranking second-best in the NFL by putting up a 50.0% third-down conversion rate. They rank 11th on defense (37.6% third-down conversion rate allowed). The Chiefs rank 16th in yards per play allowed this year (5.5), but they’ve been thriving on the offensive side of the ball, ranking third-best in the NFL with 6.2 yards per play. The Chiefs have the 19th-ranked turnover margin in the NFL at -1, forcing eight turnovers (25th in NFL) while turning it over nine times (seventh in NFL).


In terms of total offense, the Jaguars rank eighth in the NFL (367.4 total yards per game) and 16th on the other side of the ball (343.4 total yards allowed per game). With 22.1 points per game on offense, the Jaguars rank 18th in the NFL. On defense, they rank 10th, giving up 19.8 points per contest.

From an offensive angle, the Jaguars are posting 220.7 passing yards per contest (17th-ranked). They rank 22nd in the NFL on the other side of the ball (238.3 passing yards surrendered per game). The Jaguars rank seventh in the NFL with 146.8 rushing yards per contest on offense, and they rank seventh with 105.1 rushing yards allowed per contest on the defensive side of the ball.

The Jaguars rank eighth in the NFL with a 43.8% third-down conversion rate on offense, and 15th with a 39.6% third-down percentage allowed on defense. The Jaguars are accumulating 5.7 yards per play on offense this season (10th-ranked). Meanwhile, they are allowing 5.4 yards per play (13th-ranked) on defense. After forcing 11 turnovers (14th in NFL) and turning the ball over 13 times (23rd in NFL) this season, the Jaguars own the 20th-ranked turnover margin of -2.

Chiefs vs. Jaguars Injury Report


Player Pos. Injury Status
Jerick McKinnon RB Knee Questionable
Mecole Hardman WR Abdomen Out


Player Pos. Injury Status

Chiefs vs. Jaguars Betting Analysis

Chiefs Betting Insights

The Chiefs have covered the spread three times in eight games with a set spread. The Chiefs have yet to cover a spread when playing as at least 9-point favorites (0-1).

This season, four Chiefs games have gone over the point total. The Chiefs won 12 of the 17 games they were the moneyline favorite last season (70.6%).

The Chiefs won all four games they played as a moneyline favorite with odds of -410 or shorter.

Jaguars Betting Insights

The Jaguars have covered the spread three times this season (3-6-0).

Jaguars games have gone over the total four times this year. This season, the Jaguars have been the underdog seven times and won three of those games.

The Jaguars have not entered a game this season as a bigger underdog on the moneyline than the +330 odds on them winning this game.


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Chiefs vs. Jaguars Against The Spread & Betting Records


Overall Home Away
Point Total AVG 50.4 50.8 50.1
Implied Total AVG 27.9 28.8 27.0
ATS Record 3-5-0 0-4-0 3-1-0
Over/Under Record 4-4-0 1-3-0 3-1-0
Moneyline Favorite Record 5-1 3-0 2-1
Moneyline Underdog Record 1-1 0-1 1-0


Overall Home Away
Point Total AVG 43.7 43.8 43.5
Implied Total AVG 23.7 23.4 24.0
ATS Record 3-6-0 2-3-0 1-3-0
Over/Under Record 4-5-0 0-5-0 4-0-0
Moneyline Favorite Record 0-2 0-2 0-0
Moneyline Underdog Record 3-4 2-1 1-3

Players to Watch


  • Patrick Mahomes II has thrown for 2,605 yards (first in the NFL), 21 touchdowns (first in the NFL) and six interceptions this year. He is averaging 325.6 yards per game and 7.9 per attempt, while completing 66.2% of his attempts.
  • To go along with his passing stats, Mahomes has 176 rushing yards (third on the Chiefs), with one rushing touchdown.
  • Travis Kelce‘s 659 receiving yards this season (seventh in the NFL) have come from 77 targets and 57 receptions (sixth in the NFL). He’s averaging 82.4 receiving yards and 7.1 catches per game, with seven receiving touchdowns (first in the NFL).
  • Clyde Edwards-Helaire has 293 rushing yards with three touchdowns (36.6 yards per game through eight games).
  • Edwards-Helaire has gotten 21 targets in the passing game and has 17 catches (2.1 per game) for 151 yards (18.9 per game) and three TDs.
  • Mecole Hardman averages 3.1 receptions and 37.1 yards per game, and has 297 total receiving yards and 25 catches. He’s gotten 34 total targets, and has caught four touchdown passes.
  • On the defensive side for the Chiefs, L’Jarius Sneed has racked up 58 tackles, 1.0 TFL, and 3.5 sacks in 2022.
  • Nick Bolton has 71 tackles, 6.0 TFL, and 2.0 sacks this season.
  • This season, Chris Jones has recorded 5.5 sacks (first on the Chiefs) to go with 5.0 TFL and 15 tackles.
  • This season, Jaylen Watson has 28 tackles, 1.0 TFL, and one interception.


  • Trevor Lawrence has passed for 2,075 yards this year (to rank ninth in the NFL), with 11 touchdowns and six interceptions. He is completing 64.3% of his attempts while averaging 230.6 yards per game and 6.7 per attempt.
  • On the ground, Lawrence has added three rushing touchdowns and 152 rushing yards (second on the Jaguars).
  • Travis Etienne has scored four rushing touchdowns, while totaling 680 rushing yards (5.7 per carry and 75.6 per game).
  • Etienne has also collected 174 receiving yards (19.3 per game) on 19 catches (2.1 per game). He’s been targeted 28 times and is still looking for his first receiving touchdown.
  • This season, Christian Kirk has caught 43 passes for 574 receiving yards with five touchdowns through the air (eighth in the NFL). He has been targeted 70 total times and is averaging 4.8 receptions per game over nine games played.
  • Zay Jones has 39 catches for 349 yards and one receiving touchdown. He averages 4.9 yards per game in eight games and has been targeted 55 times.
  • Foyesade Oluokun’s 2022 effort includes 88 tackles, 7.0 TFL, and 1.0 sack through nine games. He leads the Jaguars and is fourth in the NFL in tackles.
  • Devin Lloyd has two interceptions on top of 69 tackles and seven passes defended.
  • Rayshawn Jenkins has intercepted one pass on top of 53 tackles, 1.0 TFL, and nine passes defended during the 2022 campaign.
  • Andre Cisco has totaled 46 tackles and two interceptions through nine games.

Chiefs vs. Jaguars Predictions and Pick

Our prediction to win this matchup is the Chiefs, and we predict that Chiefs will cover the spread (Chiefs -9). Finally, we see the scoring in this one going under the posted total of 51 points.


4.9/5 Read Review

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How to Bet on Chiefs vs. Jaguars

You can bet on Chiefs vs. Jaguars at every legal online sportsbook. For more NFL odds, including moneylines, spreads, over/under totals as well as NFL prop odds, check out the latest NFL lines as well as our guide to the best NFL betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Chiefs vs. Jaguars picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on football? Check out our complete guide to sports betting.


Andy Molitor

Andy has been involved in sports betting on and off his entire adult life and has been creating content surrounding it for the past five years. While the NFL is his first love, he also bets hundreds of college basketball games every winter and loves sweating golf DFS during the football offseason.

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