Browns vs. Steelers Prediction: Week 3 Odds, Picks & Moneyline – September 22, 2022

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The Cleveland Browns (1-1) host a fellow AFC North opponent on Thursday, September 22, 2022, when they square off against the Pittsburgh Steelers (1-1) at FirstEnergy Stadium.

Browns vs. Steelers Odds

Point Spread

The spread for this matchup is set at 4.5 points, with oddsmakers listing the Browns as the favorites.


As for the moneyline, the Browns have -190 odds to pick up the win, while the Steelers are listed at +160 to claim victory.


Finally, the total for the game is set at 38.5 points.


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Game Info

How to Watch Browns vs. Steelers Live?

  • Game Day: Thursday, September 22, 2022
  • Game Time: 8:15 PM ET
  • Location: Cleveland, Ohio
  • Stadium: FirstEnergy Stadium

Betting Preview


  • The Browns are putting up 380 yards per game offensively this season (ninth in NFL), and they are surrendering 331.5 yards per game (15th) on the other side of the ball.
  • The Browns are totaling 28 points per game on offense this year (seventh in NFL), and they are giving up 27.5 points per game (26th) on the other side of the ball.
  • The Browns are totaling 179.5 passing yards per game on offense this season (26th in NFL), and they are allowing 258 passing yards per game (25th) on the defensive side of the ball.
  • The Browns have been making things happen on both sides of the ball in the running game this season, as they rank best in rushing offense (200.5 rushing yards per game) and fourth-best in rushing defense (73.5 rushing yards allowed per game).
  • The Browns rank 23rd in third-down defense this year (46.2% third-down conversion rate allowed), but they’ve been playing really well on the other side of the ball, ranking fourth-best in the NFL with a 53.3% third-down percentage.
  • The Browns are gaining 5.5 yards per play (10th in the league), while giving up 5.7 per play on the defensive side of the ball (19th in the NFL) this season.
  • The Browns own the 10th-ranked turnover margin in the league at +1, forcing two turnovers (17th in NFL) while turning it over one time (first in NFL).


  • The Steelers rank third-worst in total yards per game (255), but they’ve been better on the other side of the ball, ranking 25th in the NFL with 404 total yards allowed per contest.
  • From an offensive perspective, the Steelers are posting 18.5 points per game (19th-ranked). They rank 12th in the NFL on the other side of the ball (18.5 points given up per game).
  • The Steelers have plenty of room to get better in the passing game, as they rank fifth-worst in passing yards per game (172) this season and third-worst in passing yards surrendered per game (275.5).
  • In terms of rushing, the Steelers rank 26th in the NFL on offense (83 rushing yards per game) and 22nd on defense (128.5 rushing yards allowed per game).
  • The Steelers rank 16th in third-down conversion percentage (40%) on offense, but they’ve been less productive defensively, ranking fifth-worst in the NFL with a 51.5% third-down percentage allowed.
  • The Steelers’ offense has been sputtering in terms of yards per play, ranking third-worst in the NFL at 4.3. They have been more productive defensively, giving up 5.1 yards per play (12th-ranked).
  • The Steelers own a top-five turnover margin this season, ranking second-best at +4.

Browns vs. Steelers Injury Report


Browns: TE Jesse James: Out (Biceps), DE Jadeveon Clowney: Out (Ankle), DE Chase Winovich: Out (Hamstring)


Steelers: FB Karl Joseph: Out (Ankle)

Browns vs. Steelers Betting Analysis

Browns Betting Insights

  • The Browns have covered the spread one time in two games with a set spread.
  • The Browns have yet to cover the spread (0-1) when playing as at least 4.5-point favorites.
  • Cleveland has been the moneyline favorite only one other time so far this season, a game they lost.
  • Cleveland has played as a moneyline favorite of -190 or shorter in just one game this season, which it lost.
  • This season, Browns games have hit the over twice.

Steelers Betting Insights

  • The Steelers have covered the spread once in two games with a set spread.
  • In games they have played as 4.5-point underdogs or more, the Steelers have a perfect ATS record of 1-0.
  • Pittsburgh has split the two games it has played as underdogs this season.
  • Pittsburgh has played as an underdog of +160 or more once this season and won that game.
  • Steelers games have yet to go over the total once this year.


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Browns vs. Steelers Against The Spread & Betting Records


Overall Home Away
Point Total AVG 40.3 38.5 42
Implied Total AVG 22 22 22
ATS Record 1-1-0 0-1-0 1-0-0
Over/Under Record 2-0-0 1-0-0 1-0-0
Moneyline Favorite Record 0-1 0-1 0-0
Moneyline Underdog Record 1-0 0-0 1-0


Overall Home Away
Point Total AVG 42.3 40 44.5
Implied Total AVG 24 22 26
ATS Record 1-0-1 0-0-1 1-0-0
Over/Under Record 0-2-0 0-1-0 0-1-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 1-1 0-1 1-0

Players to Watch


  • Nick Chubb has totaled 228 rushing yards (second in the NFL) with three touchdowns (114.0 yards per game through two games). His 5.8 yards per attempt rank ninth in the NFL.
  • He has also hauled in four passes (on four targets) for 28 receiving yards with zero touchdowns. He’s averaging 14.0 receving yards and 2.0 catches per game.
  • Kareem Hunt‘s rushing output this season includes 104 yards and one TD. He’s averaging 52.0 yards per game and 4.3 per attempt (25th in the NFL).
  • Hunt’s six targets in the passing game have turned into six catches (3.0 per game) for 40 yards (20.0 per game) and one touchdown.
  • Jacoby Brissett has 376 passing yards, two touchdowns and one interception this year. He has completed 65.6% of his passes, averaging 376.0 yards per game and 6.2 per attempt.
  • He has added 53 rushing yards (53.0 per game) without a touchdown on the ground.
  • Amari Cooper has 12 receptions for 118 yards and one touchdown. He’s been targeted 16 times in the air attack, and averages 6.0 receptions and 59.0 yards through two games played.
  • Over on defense, Myles Garrett has five tackles, 1.0 TFL, and 3.0 sacks in 2022.
  • Jeremiah Owusu-Koramoah has 14 tackles and 2.0 TFL this season. His tackle total leads the Browns.
  • John Johnson has put up 13 tackles and 0.5 sacks so far this year. He’s second on the Browns in tackles.
  • This season, Jadeveon Clowney has five tackles and 1.5 sacks.


  • Mitchell Trubisky is averaging 5.1 passing yards per attempt (33rd in the NFL) and 181.0 yards per game this year, completing 59.2% of his passes on the way to 362 total yards, two touchdowns and one interception through two games.
  • Najee Harris has 72 rushing yards (leading the Steelers), whithout scoring a rushing touchdown, while averaging 36.0 yards per game and 2.9 per attempt (48th in the NFL).
  • Harris also has seven catches for 43 yards (fourth on the Steelers), with one receiving touchdown. He has been targeted eight times and averages 21.5 yards per game.
  • This season, Pat Freiermuth has caught nine passes for 97 receiving yards with one touchdown in the passing game. He has been targeted 17 total times and is averaging 4.5 receptions per game through two games played.
  • Diontae Johnson has been targeted 22 times, resulting in 13 catches for 112 yards and zero receiving touchdowns.
  • Minkah Fitzpatrick’s 2022 output includes 20 tackles and two interceptions through two games. He is second on the Steelers and eighth in the league in tackles.
  • Alex Highsmith’s stat sheet includes 12 tackles, 1.0 TFL, and 3.0 sacks.
  • Myles Jack has 23 tackles.
  • Ahkello Witherspoon’s stat sheet includes one interception (sixth in the NFL) as well as 10 tackles and one pass defended in two games

Browns vs. Steelers Predictions and Pick

Our pick to win this game is the Steelers, and we predict that Steelers will cover the spread (Browns -4.5). Finally, we see the scoring in this one going over the posted total of 38.5 points.


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How to Bet on Browns vs. Steelers

You can bet on Browns vs. Steelers at every legal online sportsbook. For more NFL odds, including moneylines, spreads, over/under totals as well as NFL prop odds, check out the latest NFL lines as well as our guide to the best NFL betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Browns vs. Steelers picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on football? Check out our complete guide to sports betting.


Andy Molitor

Andy has been involved in sports betting on and off his entire adult life and has been creating content surrounding it for the past five years. While the NFL is his first love, he also bets hundreds of college basketball games every winter and loves sweating golf DFS during the football offseason.

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