76ers vs Pistons Prediction: Odds, Picks, Best Bets – Wednesday, December 21, 2022

httpscdn.dataskrive.comapiassetWzmTAKG Betsperts Media & Technology

The Philadelphia 76ers (17-12) and the Detroit Pistons (8-25) take the floor at Wells Fargo Center in a matchup on Wednesday, December 21, 2022 at 7:00 PM ET on NBCS. The 76ers are 12-point favorites in the game. The point total for the contest is set at 223.

How to bet 76ers vs. Pistons

Philadelphia 76ers vs. Detroit Pistons Odds

Point Spread

The spread for this matchup is set at 12 points, with oddsmakers listing the 76ers as the favorites.


As for the moneyline, the 76ers have -681 odds to pick up the win, while the Pistons are listed at +486 to claim victory.


Finally, the total for the game is set at 223 points.

BetMGM Risk Free First Bet up to $1000
Risk-Free Bet!

76ers vs. Pistons Game Time and How to Watch

  • Game Day: Wednesday, December 21, 2022
  • Game Time: 7:00 PM ET
  • TV Channel: NBCS
  • Location: Philadelphia, Pennsylvania
  • Arena: Wells Fargo Center

76ers vs. Pistons Betting Trends

The 76ers are 17-12-0 against the spread this season. Philadelphia has been the favorite in 17 games this season and has come away with the win 11 times (64.7%) in those contests. 76ers games this year have gone over the total in 14 out of 33 opportunities (42.4%).

Against the spread, the Pistons are 17-15-1 this year. Detroit has compiled a 7-24 record in games it was the underdog on the moneyline (winning 22.6% of those games). The Pistons have gone over the point total 60.6% of the time this season (20 of 33 games with a set point total).

FanDuel NBA Promo
$1,000 No Sweat First Bet on the NBA

Potential Starting Lineups and Key Players


76ers Leaders
Joel Embiid 21 33 9.9 4.6 1.2 1.5 1.1
James Harden 15 21.9 6.6 10.5 1.3 0.5 2.6
Tobias Harris 26 17.1 6.3 2.9 1.3 0.5 2.3
De’Anthony Melton 26 11.9 4.7 3.3 2.2 0.4 2.3
Shake Milton 25 11.2 3.2 3.5 0.4 0.2 0.8


Pistons Leaders
Bojan Bogdanovic 32 21.1 3.5 2.5 0.6 0 2.6
Jaden Ivey 29 15.5 4.3 4 1 0.3 1.4
Saddiq Bey 29 14 4.1 1.6 0.8 0.1 1.6
Alec Burks 20 13.6 2.9 1.8 0.8 0.1 1.8
Isaiah Stewart 26 11.8 8.3 1.2 0.3 0.8 1.5
DraftKings NBA Promo
Bet $5, Win $200 on Any NBA Moneyline

76ers: Furkan Korkmaz: Questionable (Illness), Tyrese Maxey: Out (Foot)

Pistons: Cade Cunningham: Out (Shin), Isaiah Livers: Out (Shoulder)

What you need to know about the Philadelphia 76ers

Philadelphia is posting 111.2 points per game this year (20th-ranked in NBA), but it has really shined defensively, allowing just 107.9 points per game (third-best). Offensively the 76ers have played better when playing at home this season, putting up 111.8 points per game, compared to 110.3 per game on the road. The 76ers’ offense has been improved over their last 10 games, scoring 116.3 points per contest compared to the 111.2 they’ve averaged this year.

Philadelphia is making 12.7 threes per game this year (10th-ranked in NBA), and it owns a 38.5% three-point percentage (third-best). The 76ers have taken 60.4% two-pointers and 39.6% from beyond the arc this year. Of the team’s baskets, 67.8% are two-pointers and 32.2% are threes.

Caesars NBA Promo
$1,250 first bet, reward credits, plus free bets on the NBA

What you need to know about the Detroit Pistons

Detroit is 19th in the league in points scored (111.3 per game) and second-worst in points conceded (118.2). The Pistons are scoring more points at home (112.1 per game) than on the road (110.5). While the Pistons are posting 111.3 points per game in 2022-23, they have improved that mark in their last 10 games, producing 116.3 a contest.

At 11.6 made 3-pointers per game and shooting 34.7% from downtown, Detroit is 14th and 18th in the league, respectively, in those categories. The Pistons take 62% percent of their shots from inside the arc, and 38% percent from beyond it. In terms of makes, 70.7% of the Pistons’ buckets are 2-pointers, and 29.3% are 3-pointers.

76ers vs. Pistons Predictions and Pick

Caesars NBA Promo
$1,250 first bet, reward credits, plus free bets on the NBA
DraftKings NBA Promo
Bet $5, Win $200 on Any NBA Moneyline
FanDuel NBA Promo
$1,000 No Sweat First Bet on the NBA
BetMGM NBA Promo
Get this BetMGM Bet $10, Get $200 on the NBA offer

You can bet on 76ers vs. Pistons at every legal online sportsbook. For more NBA odds, including moneylines, spreads, over/under totals as well as NBA prop odds, check out the latest NBA lines as well as our guide to the best NBA betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s 76ers vs. Pistons picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on basketball? Check out our complete guide to sports betting.


Luis Escalante

Luis has been a regular contributor to 4for4 since 2014 and is currently the Director of Strategy at Betsperts Group. Luis comes from an analytics background, leveraging his data skills with multiple years of experience in NFL, fantasy football, daily fantasy sports, and betting.

Deals of the Day

See All