White Sox vs Guardians Odds, Picks & Predictions – July 23

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The Cleveland Guardians (47-44) will try to extend a four-game winning streak on Saturday against the Chicago White Sox (46-47), with first pitch at 1:10 PM ET at Guaranteed Rate Field. The White Sox will hand the ball to Johnny Cueto (4-4), and the Guardians will counter with Triston McKenzie (7-6).

The oddsmakers have spoken, making the White Sox (-178) a moderate moneyline favorite to defeat the Guardians (+151) at home. The game has an over/under set at 9.5 runs.

White Sox vs. Guardians Odds

Run Line

Chicago White Sox (-1.5)


White Sox (-178)


9.5 Runs (Over: -105, Under: -115)

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When, Where, at What Time is White Sox vs. Guardians

  • Game Day: Saturday, July 23, 2022
  • Game Time: 1:10 PM ET
  • TV Channel: NSCh,CSCh,BSGL
  • Location: Chicago, Illinois
  • Stadium: Guaranteed Rate Field

White Sox Injury Report

Jake Burger10 Day Injury ListHand
Aaron Bummer15 Day Injury ListBack
Kyle Crick15 Day Injury ListElbow
Vince Velásquez15 Day Injury ListFinger
Danny Mendick60 Day Injury ListKnee
Jonathan Stiever60 Day Injury ListBack
Garrett Crochet60 Day Injury ListElbow
Eloy JiménezDay-to-dayLeg

Guardians Injury Report

Oscar Gonzalez10 Day Injury ListRibs
Anthony Gose15 Day Injury ListTricep
Aaron Civale15 Day Injury ListWrist
Cody Morris60 Day Injury ListShoulder

Last Time Out: White Sox and Guardians

Yesterday, the Guardians picked up an 8-2 win over the White Sox, with Cal Quantrill (5.00 IP, 2 R, 6 H, 4 K) earning the win for the Guardians. Andres Gimenez finished 2-for-5 with a home run and two RBI to lead the offensive attack. Lucas Giolito (3.00 IP, 6 R, 9 H, 2 K) picked up the loss for the White Sox.

Betting Trends

White Sox Betting Records and Team Stats

The White Sox have entered the game as favorites 54 times this season and won 29, or 53.7%, of those games. Chicago has a record of 6-4 in games where oddsmakers favor them by at least -178 on the moneyline. The moneyline for this contest implies a 64% chance of a victory for the White Sox. Chicago and its opponents have gone over the total this season in 43 of their 93 opportunities. The White Sox are 44-49-0 against the spread in their 93 chances this season.

NameGPAVG (Rank)OBP (Rank)SLG (Rank)HR% (Rank)K% (Rank)BB% (Rank)
José Abreu91.305 (14).388 (11).471 (39)2.8% (88)14.5% (25)11.0% (38)
Andrew Vaughn73.299 (18).347 (46).461 (46)3.2% (73)16.4% (44)5.8% (132)
Tim Anderson67.313 (8).353 (36).417 (80)2.0% (118)13.9% (20)4.1% (152)
Josh Harrison67.233 (-).308 (-).367 (-)1.7% (-)17.1% (-)6.0% (-)
A.J. Pollock74.228 (-).268 (-).332 (-)1.4% (-)21.7% (-)5.1% (-)

Guardians Betting Records and Team Stats

The Guardians have been chosen as underdogs in 48 games this year and have walked away with the win 19 times (39.6%) in those games. This year, Cleveland has won four of 13 games when listed as at least +151 or worse on the moneyline. Sportsbooks have implied with the moneyline set for this matchup that the Guardians have a 39.8% chance of pulling out a win. Contests with Cleveland have gone over the total set by sportsbooks in 44 of 91 chances this season. The Guardians are 48-43-0 against the spread in their 91 games that had a posted line this season.

NameGPAVG (Rank)OBP (Rank)SLG (Rank)HR% (Rank)K% (Rank)BB% (Rank)
José Ramírez88.287 (29).366 (23).573 (7)5.0% (20)9.7% (4)10.5% (48)
Amed Rosario85.294 (27).333 (71).408 (94)1.1% (142)15.0% (31)5.2% (144)
Steven Kwan79.285 (33).364 (28).363 (133)0.3% (153)8.7% (2)10.0% (58)
Josh Naylor65.276 (-).329 (-).509 (-)5.2% (-)15.9% (-)7.1% (-)
Andrés Giménez80.298 (20).358 (33).488 (23)3.9% (49)21.4% (89)4.9% (146)

White Sox vs. Guardians Picks and Predictions

Our pick for this matchup is the White Sox to emerge victorious (-178 on the moneyline), while we project the scoring will go under the total (9.5 runs).

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Stacy Sailer

Stacy has been a baseball fan for as long as she can remember. She admits that she grew up as a spoiled Yankees fan in the late-90’s/early 2000’s, but has slowly evolved into a disgruntled Yankees fan due to their lone championship title in the last 21 seasons. She follows other sports, but her first love has always been baseball and loves getting to share her insight and knowledge with the Betsperts community.

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