Cubs vs Pirates Prediction: Picks, Live Odds & Start Time – September 22, 2022

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On Thursday, a matchup of NL Central rivals is on the schedule, with the Pittsburgh Pirates (54-94) hosting the Chicago Cubs (64-85) at 6:35 PM ET. The Cubs will give the start to Hayden Wesneski (1-1), and the Pirates will turn to Mitch Keller (5-11).

With moneyline odds of -113 for the Cubs versus -105 for the Pirates, this game should be a close one. The contest has a total set at 7.5.

Cubs vs. Pirates Odds

Run Line

Chicago Cubs (-1.5)

Moneyline

Cubs (-113)

Total

7.5 Runs (Over: -118, Under: -103)

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When, Where, at What Time is Cubs vs. Pirates

  • Game Day: Thursday, September 22, 2022
  • Game Time: 6:35 PM ET
  • Location: Pittsburgh, Pennsylvania
  • Stadium: PNC Park

Cubs Injury Report

Name Status Injury
Nick Madrigal 10 Day Injury List Groin
Willson Contreras 10 Day Injury List Ankle
Steven Brault 15 Day Injury List Shouder
Justin Steele 15 Day Injury List Back
Ethan Roberts 60 Day Injury List Elbow
Brad Wieck 60 Day Injury List Elbow
Jason Heyward 60 Day Injury List Knee
Kyle Hendricks 60 Day Injury List Shoulder
Alec Mills 60 Day Injury List Back
Codi Heuer 60 Day Injury List Elbow
Rafael Ortega 60 Day Injury List Finger
Nico Hoerner Day-to-day Tricep

Pirates Injury Report

Name Status Injury
David Bednar 15 Day Injury List Back
JT Brubaker 15 Day Injury List Back
Canaan Smith 60 Day Injury List Wrist
Max Kranick 60 Day Injury List Elbow
Colin Holderman 60 Day Injury List Shoulder
Yerry De Los Santos 60 Day Injury List Shoulder
Blake Cederlind 60 Day Injury List Elbow
Roberto Pérez 60 Day Injury List Hamstring
Kevin Newman Day-to-day Finger

Last Time Out: Cubs and Pirates

The Cubs were vicotrious 4-3 over the Marlins yesterday in their last game. Keegan Thompson was the winning pitcher after throwing three innings without giving up an earned run on one hit, while striking out six, while Patrick Wisdom went 1-for-4 with a home run and an RBI to lead them offensively.

The Pirates were defeated by the Yankees 14-2 yesterday. Rodolfo Castro led the way offensively after going 2-for-4 with a triple in the defeat, while Roansy Contreras took the loss on the mound, pitching four innings, giving up six earned runs on six hits while striking out 10.

Betting Trends

Cubs Betting Records and Team Stats

This season, the Cubs have been favored 46 times and won 20, or 43.5%, of those games. Chicago is 19-26 this season when entering a game favored by -113 or more on the moneyline. The sportsbooks’ moneyline implies a 53.1% chance of a victory for the Cubs. Chicago’s games have gone over the total in 62 of their 152 chances. The Cubs are 76-76-0 against the spread this season.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
Ian Happ 145 .271 (41) .342 (43) .449 (51) 2.9% (76) 23.9% (98) 9.0% (58)
Nico Hoerner 125 .291 (21) .338 (48) .421 (68) 1.9% (111) 10.7% (5) 5.5% (119)
Patrick Wisdom 123 .209 (128) .301 (115) .427 (66) 4.7% (24) 33.8% (133) 10.4% (35)
Christopher Morel 102 .238 (-) .311 (-) .427 (-) 3.6% (-) 32.6% (-) 9.0% (-)
Yan Gomes 81 .234 (-) .262 (-) .363 (-) 3.0% (-) 15.1% (-) 3.0% (-)

Pirates Betting Records and Team Stats

The Pirates have been underdogs in 136 games this season and have come away with the win 49 times (36%) in those contests. This season, Pittsburgh has come away with a win 48 times in 135 chances when named as an underdog of at least -105 or longer on the moneyline. Bookmakers have implied with the moneyline set for this matchup that the Pirates have a 51.2% chance of pulling out a win. Pittsburgh and their opponents have hit the over in 69 of their 154 games with a total set by oddsmakers this season. The Pirates are 79-75-0 against the spread in their 154 games with a line set by sportsbooks this season.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
Bryan Reynolds 133 .259 (67) .336 (51) .450 (48) 4.3% (34) 23.3% (90) 8.9% (62)
Ke’Bryan Hayes 127 .243 (93) .312 (96) .348 (123) 1.3% (123) 22.5% (86) 8.8% (65)
Ben Gamel 106 .232 (-) .321 (-) .367 (-) 2.0% (-) 23.2% (-) 10.9% (-)
Michael Chavis 127 .234 (-) .268 (-) .396 (-) 3.3% (-) 29.7% (-) 4.3% (-)
Oneil Cruz 76 .218 (-) .276 (-) .461 (-) 5.5% (-) 38.6% (-) 7.1% (-)

Cubs vs. Pirates Picks and Predictions

We predict that the Pirates will pick up the win in this matchup, and they’re our choice on the moneyline (-105). If you’re looking for a pick on the over/under, we predict the final scoring winding up over the total (7.5 runs).

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WRITTEN BY

Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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