Brewers vs Cardinals Prediction: Picks, Live Odds & Start Time

In the final game of a two-game series at American Family Field, the St. Louis Cardinals (90-65) play the Milwaukee Brewers (82-72), Wednesday at 7:40 PM ET. The Brewers will hand the ball to Brandon Woodruff (12-4), and the Cardinals will counter with Jose Quintana (6-6).

Sportsbooks have made the Brewers a decent moneyline favorite (-150) at home over the Cardinals (+129). The over/under for the Brewers-Cardinals game is set at 7.

Brewers vs. Cardinals Odds

Run Line

Milwaukee Brewers (-1.5)

Moneyline

Brewers (-150)

Total

7 Runs (Over: -121, Under: +100)

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When, Where, at What Time is Brewers vs. Cardinals

Game Day: Wednesday, September 28, 2022
Game Time: 7:40 PM ET
Location: Milwaukee, Wisconsin
Stadium: American Family Field

Brewers Injury Report

Name	Status	Injury
Luis Perdomo	15 Day Injury List	Calf
Jandel Gustave	15 Day Injury List	Forearm
Trevor Rosenthal	15 Day Injury List	Hamstring
Alex Jackson	60 Day Injury List	Wrist
Miguel Sanchez	60 Day Injury List	Elbow
Jonathan Davis	Minors	Elbow

Cardinals Injury Report

Name	Status	Injury
Tyler O’Neill	10 Day Injury List	Hamstring
Jordan Hicks	15 Day Injury List	Arm
Drew VerHagen	60 Day Injury List	Hip
Álex Reyes	60 Day Injury List	Shoulder

Last Time Out: Brewers and Cardinals

These squads meet again after the Cardinals’ 6-2 victory over the Brewers yesterday. Miles Mikolas (6.00 IP, 1 R, 4 H, 9 K) registered the win for the Cardinals. Andrew Knizner went 1-for-4 with a home run and two RBI to lead the team on offense. Adrian Houser (3.00 IP, 3 R, 2 H, 3 K) took the loss on the mound for the Brewers.

Betting Trends

Brewers Betting Records and Team Stats

The Brewers have won 68, or 57.1%, of the 119 games they’ve played as favorites this season. Milwaukee is 44-28 this season when entering a game favored by -150 or more on the moneyline. The sportsbooks’ moneyline implies a 60% chance of a victory for the Brewers. Milwaukee and its opponents have gone over the total this season in 76 of their 157 opportunities. The Brewers are 69-88-0 ATS in their 157 games with a spread this season.

Name	GP	AVG (Rank)	OBP (Rank)	SLG (Rank)	HR% (Rank)	K% (Rank)	BB% (Rank)
Willy Adames	132	.242 (96)	.305 (109)	.475 (25)	5.3% (13)	26.4% (119)	8.4% (69)
Rowdy Tellez	146	.223 (120)	.310 (98)	.469 (33)	5.9% (6)	20.4% (75)	10.5% (31)
Christian Yelich	147	.253 (73)	.354 (29)	.379 (117)	1.9% (113)	24.0% (101)	12.9% (9)
Andrew McCutchen	129	.238 (102)	.310 (98)	.390 (107)	3.0% (74)	20.8% (78)	9.0% (57)
Hunter Renfroe	118	.253 (73)	.315 (90)	.492 (16)	5.7% (7)	23.8% (98)	7.7% (81)

Cardinals Betting Records and Team Stats

The Cardinals have won in 28, or 44.4%, of the 63 contests they have been named as odds-on underdogs in this year. St. Louis has a mark of 7-15 in contests where sportsbooks favor them by +129 or worse on the moneyline. Oddsmakers have implied with the moneyline set for this matchup that the Cardinals have a 43.7% chance of pulling out a win. St. Louis and their opponents have hit the over in 75 of their 159 games with a total set by oddsmakers this season. The Cardinals have an against the spread record of 86-73-0 in 159 games with a line this season.

Name	GP	AVG (Rank)	OBP (Rank)	SLG (Rank)	HR% (Rank)	K% (Rank)	BB% (Rank)
Paul Goldschmidt	146	.318 (3)	.404 (4)	.585 (3)	5.5% (10)	21.6% (81)	12.2% (13)
Nolan Arenado	144	.294 (16)	.359 (22)	.538 (4)	4.9% (20)	11.7% (7)	8.4% (69)
Tommy Edman	150	.263 (58)	.322 (74)	.399 (97)	2.1% (109)	17.8% (52)	7.3% (84)
Brendan Donovan	119	.280 (-)	.390 (-)	.380 (-)	1.1% (-)	15.3% (-)	12.8% (-)
Albert Pujols	104	.262 (-)	.337 (-)	.520 (-)	6.3% (-)	16.1% (-)	7.8% (-)

Brewers vs. Cardinals Picks and Predictions

Our best pick for Brewers vs. Cardinals sees the Brewers (-150 on the moneyline) as the pick to win. As for the over/under, we recommend betting on the over on 7 runs.