Astros vs Diamondbacks Prediction: Picks, Live Odds & Start Time – September 28, 2022

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On Wednesday, the Arizona Diamondbacks (71-84) are visiting the Houston Astros (102-53), at 8:10 PM ET. The Astros have taken three straight. The scheduled starters are Justin Verlander (17-4) for the Astros, and Zac Gallen (12-3) for the Diamondbacks.

The oddsmakers have spoken, making the Astros (-188) a moderate moneyline favorite to defeat the Diamondbacks (+160) at home. The over/under in this contest is set at 6.5.

Astros vs. Diamondbacks Odds

Run Line

Houston Astros (-1.5)

Moneyline

Astros (-188)

Total

6.5 Runs (Over: -112, Under: -108)

2 Risk-Free Bets Up To $2,000
2 Risk-Free Bets

When, Where, at What Time is Astros vs. Diamondbacks

  • Game Day: Wednesday, September 28, 2022
  • Game Time: 8:10 PM ET
  • Location: Houston, Texas
  • Stadium: Minute Maid Park

Astros Injury Report

Name Status Injury
Jason Castro 60 Day Injury List Knee
Michael Brantley 60 Day Injury List Shoulder
Josh James 60 Day Injury List Back
Lance McCullers Jr. Day-to-day Illness
Jeremy Pena Day-to-day Head

Diamondbacks Injury Report

Name Status Injury
Keynan Middleton 15 Day Injury List Toe
Kyle Nelson 15 Day Injury List Elbow
Ryne Nelson 15 Day Injury List Arm
Nick Ahmed 60 Day Injury List Shoulder
Humberto Castellanos 60 Day Injury List Forearm
Yonny Hernandez 60 Day Injury List Calf
Tyler Gilbert 60 Day Injury List Elbow
Caleb Baragar Minors Elbow
Kristian Robinson Restricted List Personal

Last Time Out: Astros and Diamondbacks

These clubs meet again following the Astros’ 10-2 victory over the Diamondbacks yesterday. Luis Garcia (6.00 IP, 1 R, 4 H, 6 K) picked up the win for the Astros. Jose Altuve went 3-for-4 with a double, two home runs and two RBI to lead the team on offense. Zach Davies (4.00 IP, 4 R, 6 H, 3 K) was credited with the loss on the mound for the Diamondbacks.

Betting Trends

Astros Betting Records and Team Stats

The Astros have entered the game as favorites 137 times this season and won 96, or 70.1%, of those games. Houston has a record of 44-17 in games where bookmakers favor them by at least -188 on the moneyline. The bookmakers’ moneyline implies a 65.3% chance of a victory for the Astros. Houston and its opponents have hit the over in 58 of their 159 games with a total this season. The Astros have an ATS record of 87-72-0 in 159 games with a spread this season.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
Yordan Alvarez 130 .304 (7) .408 (2) .615 (2) 6.9% (2) 18.6% (60) 14.3% (5)
Alex Bregman 149 .264 (55) .372 (14) .463 (38) 3.5% (54) 11.9% (8) 13.4% (8)
Jose Altuve 135 .296 (14) .386 (7) .529 (9) 4.8% (23) 14.7% (22) 11.1% (21)
Kyle Tucker 145 .262 (61) .337 (52) .487 (19) 5.0% (17) 15.6% (27) 10.1% (37)
Yuli Gurriel 141 .238 (102) .284 (125) .356 (121) 1.4% (120) 12.8% (14) 5.2% (123)

Diamondbacks Betting Records and Team Stats

The Diamondbacks have won in 49, or 41.9%, of the 117 contests they have been named as odds-on underdogs in this year. This year, Arizona has won nine of 35 games when listed as at least +160 or worse on the moneyline. The moneyline set for this matchup implies the Diamondbacks have a 38.5% chance of walking away with the win. Arizona and its opponents have gone over the total this season in 71 of their 159 opportunities. The Diamondbacks have an against the spread mark of 90-69-0 in 159 games with a line this season.

Name GP AVG (Rank) OBP (Rank) SLG (Rank) HR% (Rank) K% (Rank) BB% (Rank)
Christian Walker 153 .232 (115) .322 (74) .473 (27) 5.7% (7) 19.9% (72) 10.7% (26)
Daulton Varsho 145 .240 (101) .307 (107) .456 (44) 4.8% (23) 24.5% (108) 8.0% (77)
Ketel Marte 137 .242 (96) .323 (70) .410 (82) 2.2% (107) 18.2% (55) 9.9% (44)
Josh Rojas 118 .266 (-) .347 (-) .380 (-) 1.7% (-) 19.1% (-) 11.1% (-)
Jake McCarthy 92 .284 (-) .348 (-) .439 (-) 2.5% (-) 21.0% (-) 7.2% (-)

Astros vs. Diamondbacks Picks and Predictions

Our prediction for Astros vs. Diamondbacks sees the Astros (-188 on the moneyline) as the pick to win. As for the over/under, we prefer the over on 6.5 runs.

2 Risk-Free Bets Up To $2,000
2 Risk-Free Bets

WRITTEN BY

Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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