Wake Forest vs. Louisville Prediction: Picks & Start Time – October 2022

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ACC foes will clash when the No. 10 Wake Forest Demon Deacons (6-1) meet the Louisville Cardinals (4-3).

Wake Forest vs. Louisville Odds

Point Spread

The spread for this matchup is set at 3.5 points, with oddsmakers listing Wake Forest as the favorites.

Moneyline

As for the moneyline, Wake Forest has -162 odds to pick up the win, while Louisville is listed at +133 to claim victory.

Over/Under

Finally, the over/under for the game is set at 65 points.

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Game Info

How to Watch Wake Forest vs. Louisville Live?

  • Game Day: Saturday, October 29, 2022
  • Game Time: 3:30 PM ET
  • TV Channel: ACC Network
  • Location: Louisville, Kentucky
  • Stadium: Cardinal Stadium

Betting Preview

Wake Forest

From an offensive standpoint, Wake Forest ranks 37th in the FBS with 439.3 yards per game. Meanwhile, its defense ranks 67th in total defense (374.7 yards allowed per contest). Wake Forest has the 53rd-ranked defense this year (24.0 points allowed per game), and has been more effective on the other side of the ball, ranking 10th-best with 41.4 points per game. On offense, Wake Forest has been a top-25 unit in terms of passing yards, ranking 19th-best in the FBS by totaling 295.7 per game. The Demon Deacons rank 82nd on defense (238.4 passing yards allowed per game). Wake Forest ranks 75th in run offense (143.6 rushing yards per game) and 57th in run defense (136.3 rushing yards allowed per game) this year. Wake Forest is averaging a 45.8% third-down percentage on offense this season (33rd in the FBS), and is giving up a 38.3% third-down conversion rate (67th) on the other side of the ball. With 12 forced turnovers (47th in the FBS) against five turnovers committed (sixth in the FBS), Wake Forest’s +7 turnover margin is the 10th-best in college football.

Louisville

In terms of total yards, Louisville ranks 57th in the FBS (418.4 total yards per game) and 48th on the other side of the ball (357.1 total yards allowed per contest). Louisville’s defense has been leading the charge for the team, as it ranks 25th-best in the FBS with 20.6 points surrendered per game. In terms of offense, it is generating 27.1 points per game, which ranks 76th. With 223.4 passing yards per game on offense, Louisville ranks 85th in the FBS. Defensively, it ranks 52nd, surrendering 217.7 passing yards per contest. Louisville is compiling 195.0 rushing yards per contest on offense this season (32nd-ranked). Meanwhile, it is allowing 139.4 rushing yards per contest (61st-ranked) on defense. Louisville ranks 81st in the FBS with a 37.5% third-down conversion rate on offense, and 36th with a 33.7% third-down percentage allowed on the defensive side of the ball. With 16 forced turnovers (eighth in the FBS) and 12 turnovers committed (85th in the FBS) this season, Louisville ranks 34th in the FBS with a turnover margin of +4.

Wake Forest vs. Louisville Betting Analysis

Wake Forest Betting Insights

Wake Forest has put together a record of 5-1-1 against the spread this season. Wake Forest is 3-1-1 ATS when playing as at least 3.5-point favorites. Games involving Wake Forest have hit the over three times this season. The Demon Deacons have won all four of the games they have been the moneyline favorite this season. The Demon Deacons have played four times as a moneyline favorite with odds of -162 or shorter, and earned a victory in each game.

Cardinals Betting Insights

Louisville is 4-3-0 against the spread this year. Louisville is a perfect 1-0 ATS when playing as at least 3.5-point underdogs. This season, Louisville games have hit the over three times. This season, the Cardinals have won two out of the three games in which they’ve been the underdog. The Cardinals have played as an underdog of +133 or more once this season and won that game.

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Wake Forest vs. Louisville Against The Spread & Betting Records

Wake Forest

Overall Home Away
Point Total AVG 63.6 62.7 66.0
Implied Total AVG 39.9 40.8 37.5
ATS Record 5-1-1 3-1-1 2-0-0
Over/Under Record 3-4-0 2-3-0 1-1-0
Moneyline Favorite Record 4-0 3-0 1-0
Moneyline Underdog Record 1-1 0-1 1-0

Cardinals

Overall Home Away
Point Total AVG 55.6 58.3 53.6
Implied Total AVG 31.1 32.3 30.3
ATS Record 4-3-0 2-1-0 2-2-0
Over/Under Record 3-4-0 1-2-0 2-2-0
Moneyline Favorite Record 2-2 2-0 0-2
Moneyline Underdog Record 2-1 0-1 2-0

Players to Watch

Wake Forest

  • As part of the Demon Deacons’ defensive unit, Rondell Bothroyd has recorded 11 tackles, 2.0 TFL, and 4.5 sacks in seven games.
  • The Demon Deacons’ defensive unit has been aided by the contributions of Kobie Turner, who has played seven games and delivered 1.0 sack to go with 3.0 TFL and 19 tackles.
  • Chase Jones has helped lead the Demon Deacons’ defense with one interception to go along with 17 tackles, 1.0 TFL, 0.5 sacks, and one pass defended in seven games.
  • Malik Mustapha, as part of the Demon Deacons’ defensive unit, has amassed 2.5 sacks to go with 2.0 TFL and 17 tackles in seven games.

Cardinals

  • Monty Montgomery has recorded one interception to go with 26 tackles, 2.0 TFL, four sacks, and one pass defended in seven games for the Cardinals.
  • In seven games for the Cardinals, Yasir Abdullah has amassed two interceptions to go with 20 tackles, 6.0 TFL, 3.5 sacks, and two passes defended.
  • YaYa Diaby has been causing chaos on defense, delivering 4.5 sacks to go with 6.0 TFL and 21 tackles for the Cardinals.
  • MoMo Sanogo has compiled 31 tackles, 3.0 TFL, and 1.5 sacks In seven games for the Cardinals.

Wake Forest vs. Louisville Predictions and Pick

Wake Forest vs. Louisville betting card

    Pick ATS:

    Demon Deacons (-3.5)

    Pick OU:

    Under (65)

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How to Bet on Wake Forest vs. Louisville

You can bet on Wake Forest vs. Louisville at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Wake Forest vs. Louisville picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this game is Wake Forest, and we predict that Wake Forest will cover the spread (Wake Forest -3.5). Finally, we see the scoring in this one going under the posted total of 65 points.

WRITTEN BY

Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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