The No. 6 USC Trojans (5-0) and Washington State Cougars (4-1) will battle in clash of Pac-12 foes at Los Angeles Memorial Coliseum in Los Angeles, California.
USC vs. Washington State Odds
Point Spread
The spread for this matchup is set at 12.5 points, with sportsbooks listing USC as the favorites.
Moneyline
As for the moneyline, USC has -474 odds to pick up the win, while Washington State is listed at +344 to claim victory.
Over/Under
Finally, the over/under for the game is set at 64 points.

Game Info
How to Watch USC vs. Washington State Live?
- Game Day: Saturday, October 8, 2022
- Game Time: 7:30 PM ET
- TV Channel: FOX
- Location: Los Angeles, California
- Stadium: Los Angeles Memorial Coliseum
Betting Preview
USC
USC ranks 57th in total defense this season (358.6 yards allowed per game), but has been playing really well on the offensive side of the ball, ranking 19th-best in the FBS with 480.4 total yards per game. USC ranks 31st in scoring defense this year (19.6 points allowed per game), but has been thriving on offense, ranking 10th-best in the FBS with 42.2 points per game. USC owns the 42nd-ranked defense this year in terms of passing yards (204.2 allowed per game), and has been better on offense, ranking 22nd-best with 296.6 passing yards per game. USC is putting up 183.8 rushing yards per game on offense, which ranks them 43rd in the FBS. The team’s defensive unit ranks 85th, giving up 154.4 rushing yards per contest. USC has the 89th-ranked defense this year in terms of third-down efficiency (41.3% third-down percentage allowed), and has been more effective on offense, ranking fifth-best with a 55.6% third-down percentage. USC has forced 15 total turnovers (first in the FBS) this season and have turned it over one time (first in the FBS) for a turnover margin of +14, the best in college football.
Washington State
From an offensive standpoint, Washington State is accumulating 378.8 total yards per contest (88th-ranked). It ranks 69th in the FBS on defense (371.8 total yards given up per game). Washington State ranks 72nd in the FBS with 29.6 points per contest, but it has been lifted up by its defense, which ranks 25th-best by giving up just 18.2 points per contest. Washington State’s defense has been a bottom-25 unit in pass defense this season, surrendering 275.4 passing yards per game, which ranks 16th-worst in the FBS. On offense, it ranks 30th with 285.0 passing yards per contest. While Washington State’s run offense has been stuck in neutral, ranking 12th-worst with 93.8 rushing yards per game, its defense ranks 19th-best with just 96.4 rushing yards allowed per contest. Washington State ranks 70th in the FBS with a 39.3% third-down conversion rate on offense, and 36th with a 31.9% third-down percentage allowed on the defensive side of the ball. Washington State has accumulated eight forced turnovers (47th in the FBS) and committed 12 turnovers (114th in the FBS) this season for a -4 turnover margin that ranks 100th in the FBS.
USC vs. Washington State Betting Analysis
USC Betting Insights
USC has put together a 3-2-0 record against the spread this season. USC has an ATS record of 1-1 when playing as at least 12.5-point favorites. Games involving USC have hit the over three times this season. The Trojans have won all five of the games they have been favored on the moneyline this season. The Trojans have played in three games as a moneyline favorite with odds of -474 or shorter and won each of them.
Cougars Betting Insights
Washington State is 4-1-0 against the spread this season. Washington State has a perfect 1-0 ATS record when playing as at least 12.5-point underdogs. Washington State games have gone over the total once this season. The Cougars have split the two games they’ve played as underdogs this season. The Cougars have played as an underdog of +344 or more once this season and won that game.

USC vs. Washington State Against The Spread & Betting Records
USC
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 65.9 | 64.5 | 68.0 |
Implied Total AVG | 41.4 | 44.0 | 37.5 |
ATS Record | 3-2-0 | 2-1-0 | 1-1-0 |
Over/Under Record | 3-2-0 | 2-1-0 | 1-1-0 |
Moneyline Favorite Record | 5-0 | 3-0 | 2-0 |
Moneyline Underdog Record | 0-0 | 0-0 | 0-0 |
Cougars
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 54.8 | 56.4 | 48.5 |
Implied Total AVG | 35.0 | 35.5 | 33.0 |
ATS Record | 4-1-0 | 3-1-0 | 1-0-0 |
Over/Under Record | 1-4-0 | 1-3-0 | 0-1-0 |
Moneyline Favorite Record | 3-0 | 3-0 | 0-0 |
Moneyline Underdog Record | 1-1 | 0-1 | 1-0 |
Players to Watch
USC
- As part of the Trojans’ defense, Shane Lee has totaled 33 tackles, 3.0 TFL, 1.5 sacks, and one interception in five games.
- With one interception to go with 35 tackles, 1.0 TFL, one sack, and one pass defended in five games, Eric Gentry has been a key piece of the Trojans’ defensive unit in 2022.
- Tuli Tuipulotu has suited up for five games, delivering 13 tackles, 6.0 TFL, and four sacks for the Trojans.
- With 25 tackles and two interceptions, Max Williams has helped lead the Trojans’ defense over five games.
Cougars
- On defense, Daiyan Henley has helped set the tone with one interception to go with 42 tackles, 6.0 TFL, four sacks, and one pass defended in five games.
- Francisco Mauigoa has been causing chaos on defense, registering one interception to go with 24 tackles, 2.0 TFL, 2.5 sacks, and one pass defended for the Cougars.
- The Cougars’ Jaden Hicks has posted one interception to go with 34 tackles, 2.0 TFL, one sack, and two passes defended in five games.
- The Cougars’ Brennan Jackson has collected 16 tackles, 6.0 TFL, and two sacks in five games.
USC vs. Washington State Predictions and Pick
USC vs. Washington State betting card
- Pick ATS:
Cougars (+12.5)
Pick OU:
Under (64)

How to Bet on USC vs. Washington State
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Our prediction to win this matchup is USC, and we expect that Washington State will cover the spread (USC -12.5). Finally, we see the scoring in this one going under the posted total of 64 points.