Pac-12 opponents will battle when the No. 6 USC Trojans (4-0) meet the Arizona State Sun Devils (1-3).
USC vs. Arizona State Odds
Point Spread
The spread for this matchup is set at 24.5 points, with oddsmakers listing USC as the favorites.
Moneyline
As for the moneyline, USC has -4650 odds to pick up the win, while Arizona State is listed at +1345 to claim victory.
Over/Under
Finally, the over/under for the game is set at 60.5 points.

Game Info
How to Watch USC vs. Arizona State Live?
- Game Day: Saturday, October 1, 2022
- Game Time: 10:30 PM ET
- TV Channel: ESPN
- Location: Los Angeles, California
- Stadium: Los Angeles Memorial Coliseum
Betting Preview
USC
USC has the 61st-ranked defense this season (365.5 yards allowed per game), and has been better on the other side of the ball, ranking 23rd-best with a tally of 479.3 yards per game. USC ranks 28th in scoring defense this year (18.3 points allowed per game), but has been shining on the offensive side of the ball, ranking 15th-best in the FBS with 42.3 points per game. USC is compiling 283.8 passing yards per game on offense, which ranks them 31st in the FBS. The defense ranks 38th, surrendering 194.5 passing yards per contest. USC is totaling 195.5 rushing yards per game on offense, which ranks them 30th in the FBS. The team’s defensive unit ranks 97th, surrendering 171.0 rushing yards per contest. On the offensive side of the ball, USC has been a top-25 unit in terms of third-down efficiency, ranking 24th-best in the FBS by putting up a 48.9% third-down percentage. The defense ranks 69th on defense (38.0% third-down percentage allowed). USC has the best turnover margin in college football at +14, forcing 14 turnovers (first in the FBS) while turning it over zero times (100th in the FBS).
Arizona State
Arizona State is generating 348.8 total yards per game on offense this season (101st-ranked). Meanwhile, it is giving up 379.5 total yards per contest (73rd-ranked). Arizona State ranks 25th-worst in points per game (22.8), but it has been more effective defensively, ranking 67th in the FBS with 25.3 points ceded per contest. From an offensive angle, Arizona State is putting up 205.3 passing yards per game (100th-ranked). It ranks 38th in the FBS on defense (194.5 passing yards allowed per game). Arizona State ranks 87th in rushing yards per game (143.5), but it has been worse on the other side of the ball, ranking 25th-worst in the FBS with 185.0 rushing yards surrendered per contest. Arizona State ranks eighth-worst in third-down conversion percentage (26.1%), but it has been more effective on the defensive side of the ball, ranking 96th in the FBS with a 41.7% third-down rate allowed. With five forced turnovers (83rd in the FBS) and six turnovers committed (61st in the FBS) this season, Arizona State ranks 100th in the FBS with a turnover margin of -1.
USC vs. Arizona State Betting Analysis
USC Betting Insights
USC has put together a 3-1-0 record against the spread this season. USC is a perfect 1-0 ATS when playing as at least 24.5-point favorites. USC games have gone over the total twice this season. The Trojans have won all four of the games they have been listed as the moneyline favorite this season. The Trojans have played as a moneyline favorite of -4650 or shorter in just one game this season, which they won.
Sun Devils Betting Insights
Arizona State has put together a record of 1-3-0 against the spread this year. This year, not one Arizona State’s games have hit the over. The Sun Devils have lost both games they’ve played as underdogs this season. The Sun Devils have not been a bigger underdog this season than the +1345 moneyline set for this game.

USC vs. Arizona State Against The Spread & Betting Records
USC
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 67.3 | 66.5 | 68.0 |
Implied Total AVG | 41.0 | 44.5 | 37.5 |
ATS Record | 3-1-0 | 2-0-0 | 1-1-0 |
Over/Under Record | 2-2-0 | 1-1-0 | 1-1-0 |
Moneyline Favorite Record | 4-0 | 2-0 | 2-0 |
Moneyline Underdog Record | 0-0 | 0-0 | 0-0 |
Sun Devils
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 55.1 | 54.2 | 58.0 |
Implied Total AVG | 37.0 | 37.7 | 35.0 |
ATS Record | 1-3-0 | 1-2-0 | 0-1-0 |
Over/Under Record | 0-4-0 | 0-3-0 | 0-1-0 |
Moneyline Favorite Record | 1-1 | 1-1 | 0-0 |
Moneyline Underdog Record | 0-2 | 0-1 | 0-1 |
Players to Watch
USC
- The Trojans’ defensive unit has been aided by the contributions of Shane Lee, who has played four games and delivered 28 tackles, 3.0 TFL, one sack, and one interception.
- As part of the Trojans’ defensive unit, Eric Gentry has compiled 0.5 sacks to go with 29 tackles and one interception in four games.
- Tuli Tuipulotu has helped lead the Trojans’ defense with 11 tackles, 5.0 TFL, three sacks, and one pass defended in four games.
- A significant part of the Trojans’ defensive unit, Max Williams has two interceptions to go with 21 tackles and two passes defended in four games.
Sun Devils
- In four games for the Sun Devils, Kyle Soelle has collected 30 tackles and two interceptions.
- Merlin Robertson has been causing chaos on defense, recording 23 tackles, 1.0 TFL, and one sack for the Sun Devils.
- Khoury Bethley has delivered 2.0 TFL and 19 tackles in four games for the Sun Devils.
- Nesta Jade Silvera has amassed 21 tackles In four games for the Sun Devils.
USC vs. Arizona State Predictions and Pick
USC vs. Arizona State betting card
- Pick ATS:
Trojans (-24.5)
Pick OU:
Under (60.5)

How to Bet on USC vs. Arizona State
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Our pick to win this matchup is USC, and we predict that USC will cover the spread (USC -24.5). Finally, we see the scoring in this one going under the posted total of 60.5 points.