UCLA vs. Colorado Prediction: Picks & Start Time – September 2022

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Pac-12 opponents will battle when the UCLA Bruins (3-0) meet the Colorado Buffaloes (0-3).

UCLA vs. Colorado Odds

Point Spread

The spread for this matchup is set at 21.5 points, with oddsmakers listing UCLA as the favorites.


As for the moneyline, UCLA has -1709 odds to pick up the win, while Colorado is listed at +885 to claim victory.


Finally, the over/under for the game is set at 57 points.


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Game Info

How to Watch UCLA vs. Colorado Live?

  • Game Day: Saturday, September 24, 2022
  • Game Time: 2:00 PM ET
  • TV Channel: Pac-12 Network
  • Location: Boulder, Colorado
  • Stadium: Folsom Field

Betting Preview


Offensively, UCLA has been a top-25 unit, ranking 15th-best in the FBS by compiling 506.0 yards per game. The defense ranks 26th (290.3 yards allowed per game). UCLA ranks 27th in scoring offense (40.7 points per game) and 39th in scoring defense (18.3 points allowed per game) this year. Offensively, UCLA has been a top-25 unit in terms of passing yards, ranking 25th-best in the FBS by compiling 295.0 per game. The Bruins rank 45th on defense (195.0 passing yards allowed per game). UCLA is putting up 211.0 rushing yards per game offensively this season (31st in the FBS), and is giving up 95.3 rushing yards per game (31st) on defense. UCLA is putting up a 50.0% third-down percentage on offense, which ranks them 26th in the FBS. Defensively, the defense ranks 82nd, surrendering a 39.1% third-down conversion rate. UCLA has forced six total turnovers (25th in the FBS) this season and have turned it over five times (72nd in the FBS) for +1a turnover margin of +1, 45th-ranked in college football.


This season has been rough for Colorado on both offense and defense, as it is averaging only 245.3 total yards per game (fifth-worst) and surrendering 452.0 total yards per game (14th-worst). Colorado has been outplayed on both sides of the ball this season, ranking third-worst in points (10.0 per game) and fifth-worst in points surrendered (42.7 per game). On the offensive side of the ball, Colorado is a bottom-25 pass offense, putting up just 125.3 passing yards per game (eighth-worst). On the bright side, it is dominating on the defensive side of the ball, surrendering only 104.0 passing yards per contest (fifth-best). Colorado ranks 100th in rushing yards per game (120.0), but it has been less productive on the defensive side of the ball, ranking worst in the FBS with 348.0 rushing yards allowed per contest. Colorado has lots of room to get better on third down, as it ranks fourth-worst in third-down conversion percentage (21.1%) and are third-worst in third-down rate allowed (57.9%). After forcing four turnovers (71st in the FBS) and turning the ball over four times (49th in the FBS) this season, Colorado sports the 100th-ranked turnover margin of 0.

UCLA vs. Colorado Betting Analysis

UCLA Betting Insights

UCLA has gone 1-2-0 against the spread this season. UCLA has 1-1 ATS when playing as at least 21.5-point favorites. UCLA games have gone over the total twice this season. The Bruins have been listed as the moneyline favorite just two other times so far this season, and they won both of the games. The Bruins have played as a moneyline favorite of -1709 or shorter in just one game this season, which they won.

Buffaloes Betting Insights

Colorado has not covered the spread in any matchup this season (0-3-0). Colorado is winless against the spread when it is 21.5-point underdogs or more (0-1). Colorado games have gone over the total twice this season. The Buffaloes have been listed as the underdog three times this season and have failed to win any of those games. The Buffaloes have played as an underdog of +885 or more once this season and lost that game.


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UCLA vs. Colorado Against The Spread & Betting Records


Overall Home Away
Point Total AVG 59.0 59.0
Implied Total AVG 44.0 44.0
ATS Record 1-2-0 1-2-0 0-0-0
Over/Under Record 2-1-0 2-1-0 0-0-0
Moneyline Favorite Record 2-0 2-0 0-0
Moneyline Underdog Record 0-0 0-0 0-0


Overall Home Away
Point Total AVG 52.5 59.5 49.0
Implied Total AVG 36.3 37.0 36.0
ATS Record 0-3-0 0-1-0 0-2-0
Over/Under Record 2-1-0 0-1-0 2-0-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 0-3 0-1 0-2

Players to Watch


  • Grayson Murphy has helped spur the Bruins’ defense with 10 tackles, 2.0 TFL, and two sacks in three games.
  • The Bruins’ defensive unit has been helped by Laiatu Latu, who has suited up for three games and delivered 2.0 sacks to go with 1.0 TFL and three tackles.
  • As part of the Bruins’ defensive unit, Stephan Blaylock has compiled four tackles, 1.0 TFL, and one sack in three games.
  • With 1.0 sack to go along with 1.0 TFL, Carl Jones has helped carry the Bruins’ defense over three games.


  • As a key defensive contributor, the Buffaloes’ Josh Chandler-Semedo has recorded 20 tackles, 2.0 TFL, and one sack in three games.
  • On defense, Quinn Perry has helped lead the charge with 24 tackles and 1.0 TFL in three games.
  • Trevor Woods has 20 tackles in three games.
  • On defense, Isaiah Lewis has racked up 14 tackles and one interception in three games.

UCLA vs. Colorado Predictions and Pick

UCLA vs. Colorado betting card

    Pick ATS:

    Bruins (-21.5)

    Pick OU:

    Over (57)


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How to Bet on UCLA vs. Colorado

You can bet on UCLA vs. Colorado at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s UCLA vs. Colorado picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this contest is UCLA, and we expect that UCLA will cover the spread (UCLA -21.5). Finally, we see the scoring in this one going over the posted total of 57 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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