Ohio State vs. Wisconsin Prediction: Picks & Start Time – September 2022

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The No. 3 Ohio State Buckeyes (3-0) and Wisconsin Badgers (2-1) will face each other in clash of Big Ten foes at Ohio Stadium in Columbus, Ohio.

Ohio State vs. Wisconsin Odds

Point Spread

The spread for this matchup is set at 19 points, with bookmakers listing Ohio State as the favorites.


As for the moneyline, Ohio State has -1115 odds to pick up the win, while Wisconsin is listed at +670 to claim victory.


Finally, the total for the game is set at 56.5 points.

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Game Info

How to Watch Ohio State vs. Wisconsin Live?

  • Game Day: Saturday, September 24, 2022
  • Game Time: 7:30 PM ET
  • TV Channel: ABC
  • Location: Columbus, Ohio
  • Stadium: Ohio Stadium

Betting Preview

Ohio State

Ohio State has been shining on both offense and defense, ranking best in total offense (565.3 yards per game) and 21st-best in total defense (278.7 yards allowed per game). Ohio State has been thriving on both sides of the ball, ranking 10th-best in scoring offense (47.7 points per game) and 23rd-best in scoring defense (14.3 points allowed per game). Offensively, Ohio State has been a top-25 unit in terms of passing yards, ranking sixth-best in the FBS by totaling 358.3 per game. The Buckeyes rank 42nd on defense (194.3 passing yards allowed per game). Ohio State owns the 34th-ranked offense this season in terms of rushing yards (207.0 per game), and has been more effective defensively, ranking 22nd-best with just 84.3 rushing yards allowed per game. Ohio State has been making things happen on both sides of the ball on third down this season, owning the third-best mark in third-down conversion rate (62.2%) and 18th-best in third-down defense (26.1% third-down percentage allowed). With two forced turnovers (111th in the FBS) against one turnover committed (fifth in the FBS), Ohio State (+1) has the 45th-ranked turnover margin in college football.


Wisconsin’s defensive unit has been paving the way for the team, as it ranks 12th-best in the FBS with 246.0 total yards ceded per game. In terms of offense, it is posting 478.7 total yards per game, which ranks 31st. Wisconsin has been keeping opposing offenses in check on defense, allowing just 8.0 points per game (eighth-best). Offensively, it ranks 32nd by piling up 39.3 points per game. Wisconsin has been excelling on pass defense, allowing only 170.0 passing yards per contest (22nd-best). On offense, it ranks 46th in the FBS by racking up 260.3 passing yards per game. Things have been going well for Wisconsin on both offense and defense, as it is compiling 218.3 rushing yards per game (24th-best) and allowing only 76.0 rushing yards per game (12th-best). Wisconsin’s third-down defense has been paving the way for the team, as it ranks 11th-best in the FBS with a 24.3% third-down conversion rate allowed. In terms of offense, it is generating a 46.7% third-down rate, which ranks 42nd. Wisconsin has generated eight forced turnovers this season and have turned it over four times, leading to a +4 turnover margin, which ranks 16th-best in the FBS.

Ohio State vs. Wisconsin Betting Analysis

Ohio State Betting Insights

Ohio State has covered the spread one time this season (1-2-0). In games it has played as 19-point favorites or more, Ohio State has an ATS record of 1-1. Games involving Ohio State have hit the over once this season. The Buckeyes have been listed as the moneyline favorite just two other times so far this season, and they won both of the games. The Buckeyes have played as a moneyline favorite of -1115 or shorter in just one game this season, which they won.

Badgers Betting Insights

Wisconsin has covered the spread two times this season (2-1-0). This season, Wisconsin games have hit the over just once. This is the first time the Badgers will play as underdogs this season. The Badgers have entered two games this season as the underdog by +670 or more and won each of those games.

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Ohio State vs. Wisconsin Against The Spread & Betting Records

Ohio State

Overall Home Away
Point Total AVG 63.3 63.3
Implied Total AVG 47.3 47.3
ATS Record 1-2-0 1-2-0 0-0-0
Over/Under Record 1-2-0 1-2-0 0-0-0
Moneyline Favorite Record 2-0 2-0 0-0
Moneyline Underdog Record 0-0 0-0 0-0


Overall Home Away
Point Total AVG 45.5 45.5
Implied Total AVG 38.3 38.3
ATS Record 2-1-0 2-1-0 0-0-0
Over/Under Record 1-2-0 1-2-0 0-0-0
Moneyline Favorite Record 0-1 0-1 0-0
Moneyline Underdog Record 0-0 0-0 0-0

Players to Watch

Ohio State

  • Tommy Eichenberg has helped carry the Buckeyes’ defense with 13 tackles, 3.0 TFL, and two sacks in three games.
  • With five tackles, 3.0 TFL, and two sacks in three games, Michael Hall Jr. has been a key contributor to the Buckeyes’ defense in 2022.
  • Javontae Jean-Baptiste has played three games, posting four tackles, 1.0 TFL, and two sacks for the Buckeyes.
  • The Buckeyes’ defense has been helped by Steele Chambers, who has suited up for three games, posting 1.0 sack to go with 2.0 TFL and eight tackles.


  • Nick Herbig has posted 11 tackles, 5.0 TFL, and four sacks in three games for the Badgers.
  • Maema Njongmeta has been providing a big boost on defense, compiling one interception to go with 18 tackles, 2.0 TFL, and one pass defended for the Badgers.
  • John Torchio has collected 1.0 sack to go with 1.0 TFL, nine tackles, and one interception in three games for the Badgers.
  • On defense, Jordan Turner has chipped in with eight tackles, 2.0 TFL, and one sack in three games.

Ohio State vs. Wisconsin Predictions and Pick

Ohio State vs. Wisconsin betting card

    Pick ATS:

    Badgers (+19)

    Pick OU:

    Over (56.5)

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How to Bet on Ohio State vs. Wisconsin

You can bet on Ohio State vs. Wisconsin at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Ohio State vs. Wisconsin picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this game is Ohio State, and we expect that Wisconsin will cover the spread (Ohio State -19). Finally, we see the scoring in this one going over the posted total of 56.5 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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