Michigan State vs. Indiana Prediction: Picks & Start Time – November 19, 2022

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The Michigan State Spartans (5-5) face a Big Ten matchup versus the Indiana Hoosiers (3-7).

Michigan State vs. Indiana Odds

Point Spread

The spread for this matchup is set at 10.5 points, with sportsbooks listing Michigan State as the favorites.


As for the moneyline, Michigan State has -407 odds to pick up the win, while Indiana is listed at +306 to claim victory.


Finally, the total for the game is set at 47 points.

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Game Info

How to Watch Michigan State vs. Indiana Live?

  • Game Day: Saturday, November 19, 2022
  • Game Time: 12:00 PM ET
  • TV Channel: BTN
  • Location: East Lansing, Michigan
  • Stadium: Spartan Stadium

Betting Preview

Michigan State

Despite having a bottom-25 defense that ranks 25th-worst in the FBS (430.0 yards allowed per game), Michigan State has put up better results offensively, ranking 104th in the FBS offensively averaging 344.2 yards per game. Offensively, Michigan State ranks 90th in the FBS with 24.6 points per game. Meanwhile, the team’s defense ranks 61st in points allowed (430.0 points allowed per contest). Michigan State ranks 62nd in pass offense (235.3 passing yards per game) and 105th in pass defense (257.4 passing yards allowed per game) this year. Michigan State ranks 17th-worst in rushing offense (108.9 rushing yards per game), but has been better on defense, ranking 97th with 172.6 rushing yards allowed per game. In addition to a 44.7% third-down percentage allowed on defense, which ranks 17th-worst in the FBS, Michigan State has put up the 71st-ranked third-down conversion rate (38.3%) on offense. With 12 forced turnovers (89th in the FBS) against 12 turnovers committed (34th in the FBS), Michigan State (0) owns the 100th-ranked turnover margin in college football.


Indiana has been outplayed on both offense and defense this season, ranking 17th-worst in total offense (323.0 total yards per game) and 13th-worst in total defense (446.3 total yards allowed per game). Indiana has not been getting things done on defense, ranking 13th-worst with 34.6 points given up per game. It has been better offensively, compiling 22.4 points per contest (102nd-ranked). Indiana’s defense has been a bottom-25 unit in pass defense this season, allowing 270.2 passing yards per game, which ranks 17th-worst in the FBS. Offensively, it ranks 59th with 237.2 passing yards per contest. Indiana ranks fifth-worst in rushing yards per game (85.8), but it has been better on the other side of the ball, ranking 99th in the FBS with 176.1 rushing yards surrendered per contest. In terms of third-down efficiency, this season has been difficult for Indiana on both sides of the ball, as it is putting up a 34.2% third-down conversion rate (25th-worst) and allowing a 42.7% conversion rate (23rd-worst). Indiana has a -6 turnover margin this season, which ranks 100th in the FBS.

Michigan State vs. Indiana Betting Analysis

Michigan State Betting Insights

Michigan State has put together a record of 5-5-0 against the spread this season. In games they have played as 10.5-point favorites or more, Michigan State has a perfect ATS record of 2-0. Michigan State games have finished with a final combined score above the over/under four times this season. The Spartans have won all three of the games they have been the moneyline favorite this season. The Spartans have played three times as a moneyline favorite with odds of -407 or shorter, and earned a victory in each game.

Hoosiers Betting Insights

Indiana have registered a 3-7-0 record against the spread this year. Indiana has an ATS record of 2-3 when playing as at least 10.5-point underdogs. Games involving Indiana have hit the over on six occasions this season. The Hoosiers have been listed as the underdog six times this season and have failed to win any of those games. The Hoosiers have been at least a +306 moneyline underdog five times this season, but lost all of those games.

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Michigan State vs. Indiana Against The Spread & Betting Records

Michigan State

Overall Home Away
Point Total AVG 52.8 52.7 52.9
Implied Total AVG 34.2 35.2 32.8
ATS Record 5-5-0 3-3-0 2-2-0
Over/Under Record 4-6-0 3-3-0 1-3-0
Moneyline Favorite Record 3-0 3-0 0-0
Moneyline Underdog Record 2-5 1-2 1-3


Overall Home Away
Point Total AVG 55.6 54.7 57.0
Implied Total AVG 35.3 34.2 37.0
ATS Record 3-7-0 3-3-0 0-4-0
Over/Under Record 6-4-0 4-2-0 2-2-0
Moneyline Favorite Record 3-0 3-0 0-0
Moneyline Underdog Record 0-6 0-3 0-3

Players to Watch

Michigan State

  • Jacoby Windmon has hit the gridiron for 10 games, totaling 5.5 sacks to go with 3.0 TFL, 48 tackles, and one interception for the Spartans.
  • Cal Haladay has hit the gridiron for 10 games, registering 94 tackles, 6.0 TFL, and 1.5 sacks for the Spartans.
  • Kendell Brooks has helped spur the Spartans’ defense with 85 tackles and 3.0 TFL in 10 games.
  • Ben VanSumeren has been a significant piece of the Spartans’ defensive unit in 2022, with 70 tackles, 1.0 TFL, and one sack in 10 games.


  • Aaron Casey has been providing a big boost on defense, compiling 58 tackles, 3.0 TFL, and 1.5 sacks for the Hoosiers.
  • In 10 games for the Hoosiers, Bradley Jennings Jr. has posted 49 tackles, 5.0 TFL, and one sack.
  • The Hoosiers’ Dasan McCullough has delivered 28 tackles, 4.0 TFL, and four sacks in 10 games.
  • Bryant Fitzgerald has amassed one interception to go with 39 tackles, 0.5 sacks, and one pass defended In 10 games for the Hoosiers.

Michigan State vs. Indiana Predictions and Pick

Michigan State vs. Indiana betting card

    Pick ATS:

    Spartans (-10.5)

    Pick OU:

    Over (47)

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How to Bet on Michigan State vs. Indiana

You can bet on Michigan State vs. Indiana at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Michigan State vs. Indiana picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this game is Michigan State, and we project that Michigan State will cover the spread (Michigan State -10.5). Finally, we see the scoring in this one going over the posted total of 47 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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