Virginia vs. Louisville Prediction: Picks & Start Time – October 2022

httpscdn.dataskrive.comapiassetejf7MJPlouisville cardinals vs virginia cavaliers Betsperts Media & Technology

The Virginia Cavaliers (2-3) and Louisville Cardinals (2-3) will battle in clash of ACC rivals at Scott Stadium in Charlottesville, Virginia.

Virginia vs. Louisville Odds

Point Spread

The spread for this matchup is set at 2 points, with sportsbooks listing Virginia as the favorites.


As for the moneyline, Virginia has -108 odds to pick up the win, while Louisville is listed at -114 to claim victory.


Finally, the total for the game is set at 49 points.

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Game Info

How to Watch Virginia vs. Louisville Live?

  • Game Day: Saturday, October 8, 2022
  • Game Time: 12:00 PM ET
  • TV Channel: ACC Network
  • Location: Charlottesville, Virginia
  • Stadium: Scott Stadium

Betting Preview


Offensively, Virginia ranks 99th in the FBS with 364.4 yards per game. Meanwhile, its defense ranks 53rd in total defense (355.4 yards allowed per contest). Virginia has been a bottom-25 scoring offense this year, ranking 14th-worst with 18.0 points per game. The defense ranks 56th in the FBS (23.0 points allowed per game). Virginia ranks 93rd in pass offense (210.0 passing yards per game) and 39th in pass defense (199.4 passing yards allowed per game) this season. Virginia is averaging 154.4 rushing yards per game on offense, which ranks them 69th in the FBS. The team’s defensive unit ranks 86th, giving up 156.0 rushing yards per game. Virginia ranks 79th in third-down efficiency (37.1%) on offense and 47th in third-down percentage allowed (34.7%) on defense this year. Virginia has the 100th-ranked turnover margin in college football at -3, forcing nine turnovers (28th in the FBS) while turning it over 12 times (115th in the FBS).


With 428.8 total yards per game on offense, Louisville ranks 53rd in the FBS in 2022. On defense, it ranks 67th, giving up 371.0 total yards per game. With 26.4 points per game on offense, Louisville ranks 90th in the FBS. Defensively, it ranks 60th, giving up 23.4 points per game. With 219.8 passing yards per game on offense, Louisville ranks 87th in the FBS. Defensively, it ranks 49th, giving up 210.6 passing yards per contest. Louisville’s run offense has been consistently moving the chains, accumulating 209.0 rushing yards per game (23rd-best) this season. Defensively, it ranks 91st by surrendering 160.4 rushing yards per game. With a 35.3% third-down conversion rate on offense, Louisville ranks 93rd in the FBS. Defensively, it ranks 51st, allowing a 34.8% third-down rate. At 0, Louisville sports the 100th-ranked turnover margin in the FBS, with nine forced turnovers (28th in the FBS) and nine turnovers committed (99th in the FBS).

Virginia vs. Louisville Betting Analysis

Virginia Betting Insights

Virginia has covered the spread once in five games with a set spread. Virginia has not covered the spread when they are at least 2-point favorites (0-2). Games involving Virginia have hit the over once this season. The Cavaliers have been the moneyline favorite only two other times so far this season, and they won both of the games. The Cavaliers have played as a moneyline favorite of -108 or shorter in just two games this season, and they won both.

Cardinals Betting Insights

Louisville has covered the spread two times in five games with a set number. Louisville is 1-1 ATS when playing as at least 2-point underdogs. Louisville games have gone over the total twice this year. The Cardinals have split the two games they’ve played as underdogs this season. The Cardinals have a record of 0-1 in games where oddsmakers have them as underdogs of at least -114 on the moneyline.

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Virginia vs. Louisville Against The Spread & Betting Records


Overall Home Away
Point Total AVG 55.3 56.8 54.3
Implied Total AVG 32.4 36.0 30.0
ATS Record 1-4-0 0-2-0 1-2-0
Over/Under Record 1-4-0 0-2-0 1-2-0
Moneyline Favorite Record 2-0 2-0 0-0
Moneyline Underdog Record 0-3 0-0 0-3


Overall Home Away
Point Total AVG 57.4 60.0 55.7
Implied Total AVG 33.0 34.5 32.0
ATS Record 2-3-0 1-1-0 1-2-0
Over/Under Record 2-3-0 1-1-0 1-2-0
Moneyline Favorite Record 1-2 1-0 0-2
Moneyline Underdog Record 1-1 0-1 1-0

Players to Watch


  • Nick Jackson has hit the gridiron for five games, recording 2.0 sacks to go with 3.0 TFL and 48 tackles for the Cavaliers.
  • With 21 tackles, 4.0 TFL, and four sacks in five games, Chico Bennett Jr. has been a significant piece of the Cavaliers’ defense in 2022.
  • Jonas Sanker has hit the gridiron for five games, collecting 35 tackles and one interception for the Cavaliers.
  • The Cavaliers’ defense has been helped by the play of Langston Long, who has played five games, delivering 2.0 TFL and 36 tackles.


  • Monty Montgomery has been doing his part on defense, compiling one interception to go with 18 tackles, 1.0 TFL, 2.5 sacks, and one pass defended for the Cardinals.
  • In five games for the Cardinals, YaYa Diaby has totaled 14 tackles, 4.0 TFL, and four sacks.
  • The Cardinals’ Yasir Abdullah has amassed one interception to go with 13 tackles, 4.0 TFL, 1.5 sacks, and one pass defended in five games.
  • MoMo Sanogo has collected 1.5 sacks to go with 2.0 TFL and 20 tackles in five games for the Cardinals.

Virginia vs. Louisville Predictions and Pick

Virginia vs. Louisville betting card

    Pick ATS:

    Cardinals (+2)

    Pick OU:

    Under (49)

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How to Bet on Virginia vs. Louisville

You can bet on Virginia vs. Louisville at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Virginia vs. Louisville picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this contest is Virginia, and we expect that Louisville will cover the spread (Virginia -2). Finally, we see the scoring in this one going under the posted total of 49 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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