Iowa State vs. Kansas Prediction: Picks & Start Time – October 2022

httpscdn.dataskrive.comapiassetAIcAxGiiowa state cyclones vs kansas jayhawks Betsperts Media & Technology

The Iowa State Cyclones (3-1) have a Big 12 matchup versus the Kansas Jayhawks (4-0).

Iowa State vs. Kansas Odds

Point Spread

The spread for this matchup is set at 3.5 points, with sportsbooks listing Iowa State as the favorites.


As for the moneyline, Iowa State has -164 odds to pick up the win, while Kansas is listed at +135 to claim victory.


Finally, the over/under for the game is set at 58.5 points.

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Game Info

How to Watch Iowa State vs. Kansas Live?

  • Game Day: Saturday, October 1, 2022
  • Game Time: 3:30 PM ET
  • TV Channel: ESPN2
  • Location: Lawrence, Kansas
  • Stadium: David Booth Memorial Stadium (Lawrence, KS)

Betting Preview

Iowa State

On defense, Iowa State has been a top-25 unit, ranking 14th-best by allowing just 266.0 yards per game. The offense ranks 76th (398.8 yards per game). Iowa State ranks 79th in points scored this year (29.8 points per game), but has been shining on the other side of the ball, ranking 17th-best in the FBS with 14.5 points allowed per game. Iowa State is compiling 265.3 passing yards per game on offense (50th in the FBS), and ranks 34th defensively with 190.3 passing yards allowed per game. Iowa State ranks 94th in rushing yards this year (133.5 rushing yards per game), but has been thriving on the other side of the ball, ranking seventh-best in the FBS with 75.8 rushing yards allowed per game. Iowa State has been making things happen on both sides of the ball on third down this season, owning the 12th-best mark in third-down conversion rate (51.7%) and 23rd-best in third-down defense (28.8% third-down conversion rate allowed). Iowa State ranks 49th in college football with a +1 turnover margin after forcing 8 turnovers (18th in the FBS) while committing seven (86th in the FBS).


In terms of total offense, Kansas ranks 32nd in the FBS (471.8 total yards per game) and 89th on the other side of the ball (400.0 total yards allowed per game). Kansas’ offense has been dominant, compiling 48.5 points per contest (fourth-best) this season. On defense, it ranks 84th by allowing 27.3 points per game. Kansas ranks 83rd in the FBS with 226.5 passing yards per contest on offense, and it ranks 99th with 262.0 passing yards ceded per game on defense. Kansas’ run offense has been consistently moving the chains, racking up 245.3 rushing yards per contest (eighth-best) this season. Defensively, it ranks 65th by giving up 138.0 rushing yards per game. Kansas’ third-down defense ranks 95th in the FBS with a 41.7% third-down conversion percentage surrendered, but it has been lifted up by its offense, which ranks second-best by posting a 66.7% third-down rate. After forcing five turnovers (81st in the FBS) and turning the ball over four times (30th in the FBS) this season, Kansas sports the 49th-ranked turnover margin of +1.

Iowa State vs. Kansas Betting Analysis

Iowa State Betting Insights

Iowa State is 2-2-0 against the spread this season. In games it has played as 3.5-point favorites or more, Iowa State has an ATS record of 1-1. Iowa State games have gone over the total twice this season. The Cyclones have been the moneyline favorite just two other times so far this season, and they split the two games. The Cyclones have played as a moneyline favorite of -164 or shorter in just one game this season, which they won.

Jayhawks Betting Insights

Kansas has covered the spread in a matchup four times this season (4-0-0). Kansas has a perfect 2-0 ATS record when playing as at least 3.5-point underdogs. Games involving Kansas have hit the over on three occasions this year. The Jayhawks have won both games they’ve played as underdogs this season. The Jayhawks have been at least a +135 moneyline underdog three times this season and won each of those games.

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Iowa State vs. Kansas Against The Spread & Betting Records

Iowa State

Overall Home Away
Point Total AVG 46.4 49.0 38.5
Implied Total AVG 30.5 33.7 21.0
ATS Record 2-2-0 1-2-0 1-0-0
Over/Under Record 2-2-0 2-1-0 0-1-0
Moneyline Favorite Record 1-1 1-1 0-0
Moneyline Underdog Record 1-0 0-0 1-0


Overall Home Away
Point Total AVG 61.1 63.5 58.8
Implied Total AVG 38.3 41.5 35.0
ATS Record 4-0-0 2-0-0 2-0-0
Over/Under Record 3-1-0 1-1-0 2-0-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 2-0 0-0 2-0

Players to Watch

Iowa State

  • As part of the Cyclones’ defensive unit, O’Rien Vance has totaled 17 tackles, 2.0 TFL, and 1.5 sacks in four games.
  • As part of the Cyclones’ defense, Gerry Vaughn has totaled 1.5 sacks to go with 14 tackles in four games.
  • With 10 tackles, 1.0 TFL, 0.5 sacks, and two interceptions in four games, Colby Reeder has been a significant piece of the Cyclones’ defense in 2022.
  • Will McDonald IV, as part of the Cyclones’ defense, has compiled 1.5 sacks to go with 1.0 TFL and eight tackles in four games.


  • Lonnie Phelps has been causing chaos on defense, registering 14 tackles, 6.0 TFL, and four sacks for the Jayhawks.
  • The Jayhawks’ Craig Young has delivered 1.0 sack to go with 2.0 TFL and 16 tackles in four games.
  • In four games for the Jayhawks, Rich Miller has amassed 19 tackles and 1.0 TFL.
  • On defense, Kenny Logan Jr. has compiled 17 tackles and one interception in four games.

Iowa State vs. Kansas Predictions and Pick

Iowa State vs. Kansas betting card

    Pick ATS:

    Jayhawks (+3.5)

    Pick OU:

    Over (58.5)

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How to Bet on Iowa State vs. Kansas

You can bet on Iowa State vs. Kansas at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Iowa State vs. Kansas picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this contest is Kansas, and we project that Kansas will cover the spread (Iowa State -3.5). Finally, we see the scoring in this one going over the posted total of 58.5 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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