The Iowa State Cyclones (3-1) have a Big 12 matchup versus the Kansas Jayhawks (4-0).
Iowa State vs. Kansas Odds
Point Spread
The spread for this matchup is set at 3.5 points, with sportsbooks listing Iowa State as the favorites.
Moneyline
As for the moneyline, Iowa State has -164 odds to pick up the win, while Kansas is listed at +135 to claim victory.
Over/Under
Finally, the over/under for the game is set at 58.5 points.

Game Info
How to Watch Iowa State vs. Kansas Live?
- Game Day: Saturday, October 1, 2022
- Game Time: 3:30 PM ET
- TV Channel: ESPN2
- Location: Lawrence, Kansas
- Stadium: David Booth Memorial Stadium (Lawrence, KS)
Betting Preview
Iowa State
On defense, Iowa State has been a top-25 unit, ranking 14th-best by allowing just 266.0 yards per game. The offense ranks 76th (398.8 yards per game). Iowa State ranks 79th in points scored this year (29.8 points per game), but has been shining on the other side of the ball, ranking 17th-best in the FBS with 14.5 points allowed per game. Iowa State is compiling 265.3 passing yards per game on offense (50th in the FBS), and ranks 34th defensively with 190.3 passing yards allowed per game. Iowa State ranks 94th in rushing yards this year (133.5 rushing yards per game), but has been thriving on the other side of the ball, ranking seventh-best in the FBS with 75.8 rushing yards allowed per game. Iowa State has been making things happen on both sides of the ball on third down this season, owning the 12th-best mark in third-down conversion rate (51.7%) and 23rd-best in third-down defense (28.8% third-down conversion rate allowed). Iowa State ranks 49th in college football with a +1 turnover margin after forcing 8 turnovers (18th in the FBS) while committing seven (86th in the FBS).
Kansas
In terms of total offense, Kansas ranks 32nd in the FBS (471.8 total yards per game) and 89th on the other side of the ball (400.0 total yards allowed per game). Kansas’ offense has been dominant, compiling 48.5 points per contest (fourth-best) this season. On defense, it ranks 84th by allowing 27.3 points per game. Kansas ranks 83rd in the FBS with 226.5 passing yards per contest on offense, and it ranks 99th with 262.0 passing yards ceded per game on defense. Kansas’ run offense has been consistently moving the chains, racking up 245.3 rushing yards per contest (eighth-best) this season. Defensively, it ranks 65th by giving up 138.0 rushing yards per game. Kansas’ third-down defense ranks 95th in the FBS with a 41.7% third-down conversion percentage surrendered, but it has been lifted up by its offense, which ranks second-best by posting a 66.7% third-down rate. After forcing five turnovers (81st in the FBS) and turning the ball over four times (30th in the FBS) this season, Kansas sports the 49th-ranked turnover margin of +1.
Iowa State vs. Kansas Betting Analysis
Iowa State Betting Insights
Iowa State is 2-2-0 against the spread this season. In games it has played as 3.5-point favorites or more, Iowa State has an ATS record of 1-1. Iowa State games have gone over the total twice this season. The Cyclones have been the moneyline favorite just two other times so far this season, and they split the two games. The Cyclones have played as a moneyline favorite of -164 or shorter in just one game this season, which they won.
Jayhawks Betting Insights
Kansas has covered the spread in a matchup four times this season (4-0-0). Kansas has a perfect 2-0 ATS record when playing as at least 3.5-point underdogs. Games involving Kansas have hit the over on three occasions this year. The Jayhawks have won both games they’ve played as underdogs this season. The Jayhawks have been at least a +135 moneyline underdog three times this season and won each of those games.

Iowa State vs. Kansas Against The Spread & Betting Records
Iowa State
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 46.4 | 49.0 | 38.5 |
Implied Total AVG | 30.5 | 33.7 | 21.0 |
ATS Record | 2-2-0 | 1-2-0 | 1-0-0 |
Over/Under Record | 2-2-0 | 2-1-0 | 0-1-0 |
Moneyline Favorite Record | 1-1 | 1-1 | 0-0 |
Moneyline Underdog Record | 1-0 | 0-0 | 1-0 |
Jayhawks
Overall | Home | Away | |
---|---|---|---|
Point Total AVG | 61.1 | 63.5 | 58.8 |
Implied Total AVG | 38.3 | 41.5 | 35.0 |
ATS Record | 4-0-0 | 2-0-0 | 2-0-0 |
Over/Under Record | 3-1-0 | 1-1-0 | 2-0-0 |
Moneyline Favorite Record | 1-0 | 1-0 | 0-0 |
Moneyline Underdog Record | 2-0 | 0-0 | 2-0 |
Players to Watch
Iowa State
- As part of the Cyclones’ defensive unit, O’Rien Vance has totaled 17 tackles, 2.0 TFL, and 1.5 sacks in four games.
- As part of the Cyclones’ defense, Gerry Vaughn has totaled 1.5 sacks to go with 14 tackles in four games.
- With 10 tackles, 1.0 TFL, 0.5 sacks, and two interceptions in four games, Colby Reeder has been a significant piece of the Cyclones’ defense in 2022.
- Will McDonald IV, as part of the Cyclones’ defense, has compiled 1.5 sacks to go with 1.0 TFL and eight tackles in four games.
Jayhawks
- Lonnie Phelps has been causing chaos on defense, registering 14 tackles, 6.0 TFL, and four sacks for the Jayhawks.
- The Jayhawks’ Craig Young has delivered 1.0 sack to go with 2.0 TFL and 16 tackles in four games.
- In four games for the Jayhawks, Rich Miller has amassed 19 tackles and 1.0 TFL.
- On defense, Kenny Logan Jr. has compiled 17 tackles and one interception in four games.
Iowa State vs. Kansas Predictions and Pick
Iowa State vs. Kansas betting card
- Pick ATS:
Jayhawks (+3.5)
Pick OU:
Over (58.5)

How to Bet on Iowa State vs. Kansas
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Our prediction to win this contest is Kansas, and we project that Kansas will cover the spread (Iowa State -3.5). Finally, we see the scoring in this one going over the posted total of 58.5 points.