Eastern Michigan vs. Buffalo Prediction: Picks & Start Time – September 2022

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MAC rivals will battle when the Eastern Michigan Eagles (2-1) meet the Buffalo Bulls (0-3).

Eastern Michigan vs. Buffalo Odds

Point Spread

The spread for this matchup is set at 6 points, with bookmakers listing Eastern Michigan as the favorites.


As for the moneyline, Eastern Michigan has -233 odds to pick up the win, while Buffalo is listed at +190 to claim victory.


Finally, the over/under for the game is set at 59 points.

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Game Info

How to Watch Eastern Michigan vs. Buffalo Live?

  • Game Day: Saturday, September 24, 2022
  • Game Time: 12:00 PM ET
  • TV Channel: CBS Sports Network
  • Location: Ypsilanti, Michigan
  • Stadium: Rynearson Stadium

Betting Preview

Eastern Michigan

Eastern Michigan owns the 73rd-ranked offense this season (409.7 yards per game), and have been worse defensively, ranking 21st-worst with 433.7 yards allowed per game. Eastern Michigan has the 77th-ranked scoring offense this season (31.0 points per game), and has been less effective on the other side of the ball, ranking 23rd-worst with 34.7 points allowed per game. With 282.0 passing yards allowed per game on defense, which ranks 15th-worst in the FBS, Eastern Michigan has had to lean on their 63rd-ranked passing offense (249.0 passing yards per contest) to keep them competitive. Eastern Michigan is compiling 160.7 rushing yards per game on offense (73rd in the FBS), and ranks 80th on defense with 151.7 rushing yards allowed per game. Eastern Michigan has struggled defensively in terms of third-down efficiency, ranking fourth-worst in the FBS (56.4% third-down percentage) this season. With the ball, however, the Eagles ranks eighth-best, putting up a 56.1% third-down percentage. With three forced turnovers (93rd in the FBS) against eight turnovers committed (115th in the FBS), Eastern Michigan’s -5-5 turnover margin ranks 100th in college football.


Buffalo ranks 94th in total yards per game (356.3), but it has been less productive defensively, ranking eighth-worst in the FBS with 469.0 total yards surrendered per contest. Buffalo ranks 105th in points per game (22.3), but it has been worse on the defensive side of the ball, ranking 21st-worst in the FBS with 35.3 points ceded per contest. Buffalo has been struggling to stop the pass, ranking 25th-worst with 272.7 passing yards surrendered per game. It has been more effective offensively, putting up 247.7 passing yards per contest (66th-ranked). Buffalo has plenty of room to get better in the running game, as it ranks 23rd-worst in rushing yards per game (108.7) and 19th-worst in rushing yards allowed per game (196.3). In terms of third-down efficiency, Buffalo ranks 69th in the FBS (39.6% third-down conversion rate) and 69th on the other side of the ball (37.1% third-down rate allowed). With five forced turnovers (48th in the FBS) and four turnovers committed (49th in the FBS) this season, Buffalo ranks 45th in the FBS with a turnover margin of +1.

Eastern Michigan vs. Buffalo Betting Analysis

Eastern Michigan Betting Insights

Eastern Michigan has covered the spread one time this season (1-2-0). Eastern Michigan is winless against the spread when it has played as 6-point or greater favorites (0-1). This season, Eastern Michigan games have hit the over twice. The Eagles have been listed as the moneyline favorite only one other time so far this season, a game they won. The Eagles have played as a moneyline favorite of -233 or shorter in just one game this season, which they won.

Bulls Betting Insights

Buffalo has covered the spread twice in three games with a set number. Buffalo is a perfect 2-0 ATS when playing as at least 6-point underdogs. Games involving Buffalo have hit the over twice this season. The Bulls have lost both games they’ve played as underdogs this season. This season, the Bulls have been at least a +190 underdog on the moneyline two times, losing each of those contests.

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Eastern Michigan vs. Buffalo Against The Spread & Betting Records

Eastern Michigan

Overall Home Away
Point Total AVG 56.8 57.5 56.5
Implied Total AVG 35.7 34.0 36.5
ATS Record 1-2-0 0-1-0 1-1-0
Over/Under Record 2-1-0 1-0-0 1-1-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 1-1 0-0 1-1


Overall Home Away
Point Total AVG 58.7 51.0 62.5
Implied Total AVG 36.3 28.0 40.5
ATS Record 2-1-0 0-1-0 2-0-0
Over/Under Record 2-1-0 1-0-0 1-1-0
Moneyline Favorite Record 0-1 0-1 0-0
Moneyline Underdog Record 0-2 0-0 0-2

Players to Watch

Eastern Michigan

  • The Eagles’ defense has been aided by the contributions of T.J. Peavy, who has played three games and delivered 10 tackles and 1.0 TFL.
  • With 10 tackles in three games, Chase Kline has been a significant contributor to the Eagles’ defensive unit in 2022.
  • Joseph Sparacio has helped lead the Eagles’ defense with 10 tackles in three games.
  • Jose Ramirez, as part of the Eagles’ defensive unit, has amassed 1.0 TFL and seven tackles in three games.


  • Shaun Dolac has posted 19 tackles, 1.0 TFL, and one sack in three games for the Bulls.
  • In three games for the Bulls, James Patterson has registered 13 tackles and 2.0 TFL.
  • Marcus Fuqua has delivered seven tackles and one interception in three games for the Bulls.
  • With five tackles in three games, Jahmin Muse has been wreaking havoc on defense for the Bulls.

Eastern Michigan vs. Buffalo Predictions and Pick

Eastern Michigan vs. Buffalo betting card

    Pick ATS:

    Bulls (+6)

    Pick OU:

    Under (59)

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How to Bet on Eastern Michigan vs. Buffalo

You can bet on Eastern Michigan vs. Buffalo at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Eastern Michigan vs. Buffalo picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is Eastern Michigan, and we project that Buffalo will cover the spread (Eastern Michigan -6). Finally, we see the scoring in this one going under the posted total of 59 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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