Duke vs. Virginia Prediction: Picks & Start Time – October 2022

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ACC rivals will do battle when the Duke Blue Devils (3-1) battle the Virginia Cavaliers (2-2) at Brooks Field at Wallace Wade Stadium in Wilmington, North Carolina.

Duke vs. Virginia Odds

Point Spread

The spread for this matchup is set at 1.5 points, with oddsmakers listing Duke as the favorites.


As for the moneyline, Duke has -126 odds to pick up the win, while Virginia is listed at +104 to claim victory.


Finally, the total for the game is set at 54.5 points.


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Game Info

How to Watch Duke vs. Virginia Live?

  • Game Day: Saturday, October 1, 2022
  • Game Time: 7:30 PM ET
  • TV Channel: RSN
  • Location: Wilmington, North Carolina
  • Stadium: Brooks Field at Wallace Wade Stadium

Betting Preview


Duke is putting up 461.0 yards per game offensively this season (37th in the FBS), and are surrendering 393.0 yards per game (85th) on defense. Duke is averaging 34.3 points per game on offense (52nd in the FBS), and ranks 39th on defense with 19.5 points allowed per game. Duke is averaging 272.5 passing yards per game on offense, which ranks them 45th in the FBS. The defense ranks 94th, allowing 252.5 passing yards per contest. Offensively, Duke ranks 40th in the FBS with 188.5 rushing yards per game. Meanwhile, the defensive unit ranks 68th in rushing yards allowed per contest (140.5). In addition to a 43.6% third-down conversion rate allowed on defense, which ranks 21st-worst in the FBS, Duke has put up the 58th-ranked third-down percentage (41.9%) on offense. Duke owns the 11th-best turnover margin in college football at +6, forcing eight turnovers (19th in the FBS) while turning it over two times (eighth in the FBS).


Virginia ranks 87th with 381.8 total yards per contest on offense, and it ranks 51st with 350.0 total yards allowed per contest on defense. Virginia’s offense has been a bottom-25 unit this season, posting 18.3 points per game, which ranks 17th-worst in the FBS. On the defensive side of the ball, it ranks 36th with 19.3 points ceded per contest. Virginia is putting up 212.0 passing yards per contest on offense this season (94th-ranked). Meanwhile, it is giving up 217.0 passing yards per game (57th-ranked) on defense. With 169.8 rushing yards per game on offense, Virginia ranks 58th in the FBS. Defensively it ranks 59th, giving up 133.0 rushing yards per game. Virginia’s third-down offense has been bottom-25 this season, generating a 32.1% third-down rate, which ranks 17th-worst in the FBS. On the defensive side of the ball, it ranks 51st with a 33.9% third-down rate ceded. With nine forced turnovers (13th in the FBS) and 10 turnovers committed (118th in the FBS) this season, Virginia ranks 100th in the FBS with a turnover margin of -1.

Duke vs. Virginia Betting Analysis

Duke Betting Insights

Duke is 2-2-0 against the spread this season. Duke has 1-1 ATS when playing as at least 1.5-point favorites. This season, Duke games have hit the over once. The Blue Devils have been listed as the moneyline favorite only one other time so far this season, a game they won. The Blue Devils have played as a moneyline favorite of -126 or shorter in only one game this season, which they won.

Cavaliers Betting Insights

Virginia has put together a record of 1-3-0 against the spread this season. Virginia has an ATS record of 1-1 when playing as at least 1.5-point underdogs. This season, not one Virginia’s games have hit the over. The Cavaliers have lost both games they’ve played as underdogs this season. The Cavaliers have been at least a +104 moneyline underdog two times this season, but lost all of those games.


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Duke vs. Virginia Against The Spread & Betting Records


Overall Home Away
Point Total AVG 56.9 52.8 61.0
Implied Total AVG 36.0 37.0 35.0
ATS Record 2-2-0 1-1-0 1-1-0
Over/Under Record 1-3-0 1-1-0 0-2-0
Moneyline Favorite Record 1-0 1-0 0-0
Moneyline Underdog Record 1-1 0-0 1-1


Overall Home Away
Point Total AVG 55.5 56.8 54.3
Implied Total AVG 33.5 36.0 31.0
ATS Record 1-3-0 0-2-0 1-1-0
Over/Under Record 0-4-0 0-2-0 0-2-0
Moneyline Favorite Record 2-0 2-0 0-0
Moneyline Underdog Record 0-2 0-0 0-2

Players to Watch


  • As part of the Blue Devils’ defensive unit, Brandon Johnson has posted three tackles, one sack, and one interception in four games.
  • As part of the Blue Devils’ defensive unit, DeWayne Carter has registered 1.5 sacks to go with 1.0 TFL and three tackles in four games.
  • Jaylen Stinson has suited up for four games, registering five tackles, 1.0 TFL, and one sack for the Blue Devils.
  • A key part of the Blue Devils’ defense, Ja’Mion Franklin has three tackles, 1.0 TFL, and 1.5 sacks in four games.


  • Nick Jackson has been causing chaos on defense, registering 38 tackles, 3.0 TFL, and two sacks for the Cavaliers.
  • On defense, Chico Bennett Jr. has helped keep opposing offenses in check with 17 tackles, 4.0 TFL, and four sacks in four games.
  • In four games for the Cavaliers, Langston Long has recorded 30 tackles and 2.0 TFL.
  • Jonas Sanker has amassed one interception to go with 25 tackles and one pass defended In four games for the Cavaliers.

Duke vs. Virginia Predictions and Pick

Duke vs. Virginia betting card

    Pick ATS:

    Blue Devils (-1.5)

    Pick OU:

    Under (54.5)


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How to Bet on Duke vs. Virginia

You can bet on Duke vs. Virginia at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Duke vs. Virginia picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is Duke, and we predict that Duke will cover the spread (Duke -1.5). Finally, we see the scoring in this one going under the posted total of 54.5 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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