Clemson vs. Louisville Prediction: Picks & Start Time – November 2022

httpscdn.dataskrive.comapiassetVkxg5vbclemson tigers vs louisville cardinals Betsperts Media & Technology

The No. 12 Clemson Tigers (8-1) have an ACC matchup versus the Louisville Cardinals (6-3).

Clemson vs. Louisville Odds

Point Spread

The spread for this matchup is set at 7 points, with bookmakers listing Clemson as the favorites.

Moneyline

As for the moneyline, Clemson has -279 odds to pick up the win, while Louisville is listed at +220 to claim victory.

Over/Under

Finally, the total for the game is set at 52 points.

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Game Info

How to Watch Clemson vs. Louisville Live?

  • Game Day: Saturday, November 12, 2022
  • Game Time: 3:30 PM ET
  • TV Channel: ESPN
  • Location: Berkeley, California
  • Stadium: Memorial Stadium

Betting Preview

Clemson

Clemson is compiling 406.8 yards per game on offense, which ranks 60th in the FBS. On defense, the Tigers rank 29th, giving up 335.2 yards per game. Clemson ranks 30th in scoring offense (34.6 points per game) and 34th in scoring defense (21.6 points allowed per game) this year. Clemson is totaling 231.1 passing yards per game on offense this season (72nd in the FBS), and is surrendering 226.6 passing yards per game (65th) on the other side of the ball. Clemson ranks 49th in rushing yards this season (175.7 rushing yards per game), but has been playing really well on the defensive side of the ball, ranking 15th-best in the FBS with 108.7 rushing yards allowed per game. On the offensive side of the ball, Clemson has been a top-25 unit in terms of third-down efficiency, ranking 18th-best in the FBS by averaging a 48.1% third-down conversion rate. The defense ranks 58th on defense (37.2% third-down percentage allowed). With 11 forced turnovers (88th in the FBS) against 11 turnovers committed (38th in the FBS), Clemson (0) has the 100th-ranked turnover margin in college football.

Louisville

From an offensive angle, Louisville is compiling 422.9 total yards per contest (45th-ranked). It ranks 32nd in the FBS defensively (343.9 total yards allowed per game). Louisville has been dominant on defense, surrendering only 19.4 points per game (20th-best). On offense, it ranks 56th by compiling 30.2 points per game. From an offensive standpoint, Louisville is posting 220.7 passing yards per contest (87th-ranked). It ranks 37th in the FBS on defense (209.6 passing yards given up per game). Louisville’s rushing attack has been leading the way for the team, as it ranks 25th-best in the FBS with 202.2 rushing yards per game. In terms of defense, it is allowing 134.3 rushing yards per game, which ranks 50th. From an offensive perspective, Louisville is posting a 38.0% third-down conversion percentage (80th-ranked). It ranks 36th in the FBS on the other side of the ball (34.2% third-down rate allowed). Louisville has excelled in terms of turnovers, as the team’s turnover margin of +10 ranks fifth-best in the FBS, with 24 forced turnovers (first in the nation) and 14 turnovers committed (75th in the nation).

Clemson vs. Louisville Betting Analysis

Clemson Betting Insights

Clemson has covered the spread four times in nine games with a set spread. Clemson has an ATS record of 2-4 when playing as at least 7-point favorites. This season, Clemson games have hit the over five times. The Tigers have been favored on the moneyline eight total times this season. They’ve finished 7-1 in those games. The Tigers have played five times as a moneyline favorite with odds of -279 or shorter, and claimed a victory in each game.

Cardinals Betting Insights

Louisville has covered the spread six times over nine games with a set total. Louisville’s games have finished with a final combined score above the over/under four times this season. This season, the Cardinals have been the underdog four times and won three of those games. The Cardinals have not entered a game this season as a bigger underdog on the moneyline than the +220 odds on them winning this game.

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Clemson vs. Louisville Against The Spread & Betting Records

Clemson

Overall Home Away
Point Total AVG 51.3 52.1 50.7
Implied Total AVG 34.8 38.8 31.6
ATS Record 4-5-0 1-3-0 3-2-0
Over/Under Record 5-4-0 2-2-0 3-2-0
Moneyline Favorite Record 7-1 3-0 4-1
Moneyline Underdog Record 0-0 0-0 0-0

Cardinals

Overall Home Away
Point Total AVG 56.5 58.8 53.6
Implied Total AVG 31.4 32.4 30.3
ATS Record 6-3-0 4-1-0 2-2-0
Over/Under Record 4-5-0 2-3-0 2-2-0
Moneyline Favorite Record 3-2 3-0 0-2
Moneyline Underdog Record 3-1 1-1 2-0

Players to Watch

Clemson

  • With 5.5 sacks to go with 4.0 TFL and 24 tackles in nine games, Myles Murphy has been a big contributor to the Tigers’ defense in 2022.
  • Barrett Carter has helped carry the Tigers’ defense with 2.0 sacks to go along with 3.0 TFL, 34 tackles, and one interception in nine games.
  • The Tigers’ defensive unit has been helped by the play of K.J. Henry, who has suited up for nine games and amassed 26 tackles, 4.0 TFL, and two sacks.
  • A big contributor to the Tigers’ defensive unit, Trenton Simpson has 44 tackles and 0.5 sacks in nine games.

Cardinals

  • On defense, Yasir Abdullah has helped keep opposing offenses in check with two interceptions to go with 27 tackles, 6.0 TFL, 4.5 sacks, and two passes defended in nine games.
  • Monty Montgomery has totaled 27 tackles, 2.0 TFL, four sacks, and two interceptions in nine games for the Cardinals.
  • MoMo Sanogo has 2.5 sacks to go with 4.0 TFL and 40 tackles in nine games.
  • On defense, YaYa Diaby has supplied 22 tackles, 7.0 TFL, and 5.5 sacks in nine games.

Clemson vs. Louisville Predictions and Pick

Clemson vs. Louisville betting card

    Pick ATS:

    Cardinals (+7)

    Pick OU:

    Over (52)

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How to Bet on Clemson vs. Louisville

You can bet on Clemson vs. Louisville at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Clemson vs. Louisville picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our prediction to win this contest is Clemson, and we project that Louisville will cover the spread (Clemson -7). Finally, we see the scoring in this one going over the posted total of 52 points.

WRITTEN BY

Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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