Clemson vs. Louisiana Tech Prediction: Picks & Start Time – September 17

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The No. 5 Clemson Tigers (2-0) and Louisiana Tech Bulldogs (1-1) will face each other in a matchup at Memorial Stadium in Berkeley, California.

Clemson vs. Louisiana Tech Odds

Point Spread

The spread for this matchup is set at 34 points, with bookmakers listing Clemson as the favorites.


As for the moneyline, Clemson has -10000 odds to pick up the win, while Louisiana Tech is listed at +3000 to claim victory.


Finally, the over/under for the game is set at 53.5 points.


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Game Info

How to Watch Clemson vs. Louisiana Tech Live?

  • Game Day: Saturday, September 17, 2022
  • Game Time: 8:00 PM ET
  • TV Channel: ACC Network
  • Location: Berkeley, California
  • Stadium: Memorial Stadium

Betting Preview


  • Clemson racked up 7.7 fewer points per game (26.3) than Louisiana Tech surrendered (34.0) last year.
  • When the Tigers recorded more than 34.0 points last year, they were 1-2 against the spread and 3-0 overall.
  • Clemson racked up 74.8 fewer yards per game (359.2) than Louisiana Tech allowed per matchup (434.0) last year.
  • In games that the Tigers picked up more than 434.0 yards last season, the team was 1-3 against the spread and 4-0 overall.
  • Last season, Clemson ran for just 1.8 more yards (168.0) than Louisiana Tech allowed per outing (166.2).
  • When the Tigers ran for more than 166.2 yards last season, they compiled a 3-2 ATS record and a 5-0 overall record.

Louisiana Tech

  • Last year Louisiana Tech put up 13.2 more points per game (28.0) than Clemson gave up (14.8).
  • The Bulldogs were 4-7 against the spread and 3-8 overall in games when they recorded more than 14.8 points last year.
  • Louisiana Tech averaged 77.6 more yards per game (383.9) than Clemson gave up per outing (306.3) last season.
  • In games that the Bulldogs piled up more than 306.3 yards last season, the team was 4-5 against the spread and 2-7 overall.
  • Louisiana Tech rushed for 122.2 yards per game last season, 24.7 more than the 97.5 Clemson allowed per contest.
  • The Bulldogs had a 4-4 ATS record and a 2-6 overall record when the team ran for over 97.5 yards last year.

Clemson vs. Louisiana Tech Betting Analysis

Clemson Betting Insights

  • Clemson’s record against the spread last year was 5-8-0.
  • Clemson failed to notch a win ATS (0-2) as at least 34-point favorites last year.
  • The Tigers won 80% of the games last season when they were favored on the moneyline (8-2).
  • The Tigers did not play a game last season with moneyline odds of -10000 or shorter.
  • In 13 Clemson games last year, four went over the total.

Bulldogs Betting Insights

  • Louisiana Tech posted a 4-8-0 record against the spread last year.
  • Last season, the Bulldogs were listed as the underdog in five games and failed to win any of those contests.
  • The Bulldogs were not a bigger underdog last season than the +3000 moneyline set for this game.
  • There were nine Louisiana Tech games (out of 12) that hit the over last season.

Clemson vs. Louisiana Tech Against The Spread & Betting Records


Overall Home Away
Point Total AVG 48.7 51.6 45.3
Implied Total AVG 31.8 36.4 26.5
ATS Record 5-8-0 2-5-0 3-3-0
Over/Under Record 4-8-1 2-4-1 2-4-0
Moneyline Favorite Record 8-2 4-1 4-1
Moneyline Underdog Record 0-1 0-0 0-1


Overall Home Away
Point Total AVG 57.1 61.0 53.3
Implied Total AVG 34.0 35.7 32.3
ATS Record 4-8-0 2-4-0 2-4-0
Over/Under Record 9-3-0 5-1-0 4-2-0
Moneyline Favorite Record 3-4 3-1 0-3
Moneyline Underdog Record 0-5 0-2 0-3

Last Season’s Leaders


  • As a key defensive contributor, Trenton Simpson totaled 57 tackles, 10.0 TFL, and 6.5 sacks in 13 games last year.
  • Myles Murphy registered 8.0 sacks to go with 11.0 TFL and 38 tackles in 13 games.
  • James Skalski recorded 2.5 sacks to go with 2.0 TFL and 78 tackles a season ago.
  • On defense in 2021, Baylon Spector piled up 64 tackles, 3.0 TFL, 2.5 sacks, and one interception over 13 games.


  • Tyler Grubbs hit the gridiron for 12 games, recording 2.0 sacks to go with 7.0 TFL and 80 tackles.
  • Trey Baldwin was on the field for 12 games, compiling one interception to go along with 81 tackles, 5.0 TFL, and one pass defended.
  • Bee Jay Williamson was on the field for 12 games and registered three interceptions to go along with 43 tackles and three passes defended.
  • A key player on defense, Jaiden Cole had two interceptions to go with 40 tackles, 2.0 TFL, one sack, and two passes defended.

Clemson vs. Louisiana Tech Predictions and Pick

Clemson vs. Louisiana Tech betting card

    Pick ATS:

    Bulldogs (+34)

    Pick OU:

    Under (53.5)

How to Bet on Clemson vs. Louisiana Tech

You can bet on Clemson vs. Louisiana Tech at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Clemson vs. Louisiana Tech picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is Clemson, and we project that Louisiana Tech will cover the spread (Clemson -34). Finally, we see the scoring in this one going under the posted total of 53.5 points.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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