Arizona vs. Colorado Prediction: Picks & Start Time – October 2022

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The Arizona Wildcats (2-2) and Colorado Buffaloes (0-4) will battle in clash of Pac-12 foes at Arizona Stadium in Tucson, Arizona.

Arizona vs. Colorado Odds

Point Spread

The spread for this matchup is set at 17.5 points, with oddsmakers listing Arizona as the favorites.


As for the moneyline, Arizona has -950 odds to pick up the win, while Colorado is listed at +597 to claim victory.


Finally, the total for the game is set at 57.5 points.

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Game Info

How to Watch Arizona vs. Colorado Live?

  • Game Day: Saturday, October 1, 2022
  • Game Time: 9:30 PM ET
  • TV Channel: Pac-12 Network
  • Location: Tucson, Arizona
  • Stadium: Arizona Stadium

Betting Preview


Arizona is totaling 426.8 yards per game offensively this season (59th in the FBS), and are surrendering 416.0 yards per game (105th) on the other side of the ball. With 34.0 points allowed per game on defense, which ranks 24th-worst in the FBS, Arizona has been forced to lean on their 81st-ranked offense (29.3 points per contest) to keep them in games. Arizona owns the 32nd-ranked defense this season in terms of passing yards (187.8 allowed per game), and has been more effective offensively, ranking 21st-best with 301.3 passing yards per game. With 228.3 rushing yards allowed per game on defense, which ranks seventh-worst in the FBS, Arizona has had to lean on their 105th-ranked running game (125.5 rushing yards per contest) to keep them competitive. Arizona is posting a 37.5% third-down conversion rate on offense, which ranks them 79th in the FBS. On the defensive side of the ball, the defense ranks 58th, allowing a 35.9% third-down conversion rate. Arizona ranks 100th in college football with a -2 turnover margin after forcing 6 turnovers (56th in the FBS) and committing eight (98th in the FBS).


Colorado has lots of room to improve, as it ranks seventh-worst in total yards per game (261.3) and 10th-worst in total yards allowed per game (467.8). This season has been difficult for Colorado on both sides of the ball, as it is putting up just 11.8 points per game (third-worst) and ceding 43.3 points per game (sixth-worst). Colorado ranks 17th-worst in passing yards per game on offense (158.5), but at least it has been playing well on defense, ranking eighth-best in passing yards allowed per game (144.5). Colorado has plenty of room to improve in the running game, as it ranks 18th-worst in rushing yards per game (102.8) and worst in rushing yards allowed per game (323.3). Colorado has struggled on both offense and defense on third down this season, ranking sixth-worst in third-down conversion rate (23.6%) and third-worst in third-down percentage allowed (55.3%). After forcing four turnovers (101st in the FBS) and turning the ball over six times (66th in the FBS) this season, Colorado sports the 100th-ranked turnover margin of -2.

Arizona vs. Colorado Betting Analysis

Arizona Betting Insights

Arizona has covered the spread two times over four games with a set spread. This season, three Arizona games have gone over the point total. This is the first game this season the Wildcats are playing as the moneyline favorite. The Wildcats have yet to play a game with moneyline odds of -950 or shorter.

Buffaloes Betting Insights

Colorado is winless against the spread this season (0-4-0). Colorado is winless against the spread when it’s 17.5-point underdogs or more (0-3). Colorado’s games have finished with a final combined score above the over/under three times this year. The Buffaloes have been the underdog in four games this season, and they have failed to win any of those contests. This season, the Buffaloes have been at least a +597 underdog on the moneyline three times, losing each of those contests.

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Arizona vs. Colorado Against The Spread & Betting Records


Overall Home Away
Point Total AVG 50.4 52.8 48.0
Implied Total AVG 28.5 30.5 26.5
ATS Record 2-2-0 1-1-0 1-1-0
Over/Under Record 3-1-0 1-1-0 2-0-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 2-2 1-1 1-1


Overall Home Away
Point Total AVG 53.6 58.3 49.0
Implied Total AVG 37.3 38.5 36.0
ATS Record 0-4-0 0-2-0 0-2-0
Over/Under Record 3-1-0 1-1-0 2-0-0
Moneyline Favorite Record 0-0 0-0 0-0
Moneyline Underdog Record 0-4 0-2 0-2

Players to Watch


  • Jaxen Turner has helped lead the Wildcats’ defense with 23 tackles, 1.0 TFL, and one interception in four games.
  • As part of the Wildcats’ defensive unit, Hunter Echols has posted 1.0 sack to go with 3.0 TFL and 20 tackles in four games.
  • Jerry Roberts has helped spur the Wildcats’ defense with 34 tackles in four games.
  • A big contributor to the Wildcats’ defensive unit, Jalen Harris has 17 tackles, 1.0 TFL, and 1.5 sacks in four games.


  • Josh Chandler-Semedo has been providing a big boost on defense, recording 25 tackles, 4.0 TFL, and two sacks for the Buffaloes.
  • The Buffaloes’ Quinn Perry has posted 1.0 TFL and 32 tackles in four games.
  • Trevor Woods has 27 tackles in four games.
  • On defense, Isaiah Lewis has chipped in with 21 tackles and one interception in four games.

Arizona vs. Colorado Predictions and Pick

Arizona vs. Colorado betting card

    Pick ATS:

    Buffaloes (+17.5)

    Pick OU:

    Over (57.5)

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How to Bet on Arizona vs. Colorado

You can bet on Arizona vs. Colorado at every legal online sportsbook. For more college football odds, including moneylines, spreads, over/under totals as well as college football prop odds, check out the latest college football lines as well as our guide to the best college football betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Arizona vs. Colorado picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college football? Check out our complete guide to sports betting.

Our pick to win this contest is Arizona, and we project that Colorado will cover the spread (Arizona -17.5). Finally, we see the scoring in this one going over the posted total of 57.5 points.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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