Iowa State vs Pittsburgh Prediction: Picks, Live Odds & Moneyline – Friday, March 17, 2023

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The No. 6 seed Iowa State Cyclones (19-13) and the No. 11 seed Pittsburgh Panthers (23-11) meet on Friday at 3:10 PM in the first round of the NCAA Tournament. The matchup airs on truTV.

Friday’s matchup between the Cyclones and the Panthers features the Cyclones as 4.5-point favorites. The point total for the game is set at 131.5.

Iowa State vs. Pittsburgh Odds

Point Spread for Iowa State vs. Pittsburgh

The spread for this matchup is set at 4.5 points, with oddsmakers listing Iowa State as the favorite.

Iowa State vs. Pittsburgh Moneyline

As for the moneyline, Iowa State has -198 odds to pick up the win, while Pittsburgh is listed at +165 to claim victory.


Finally, the total for the game is set at 131.5 points.

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Game Time and How to Watch

  • Game Day: Friday, March 17, 2023
  • Game Time: 3:10 PM ET
  • TV Channel: truTV
  • Location: Greensboro, North Carolina
  • Arena: Greensboro Coliseum

Iowa State vs. Pittsburgh Betting Trends

Iowa State has played 32 games, with 16 wins against the spread. The Cyclones have been chosen as favorites in 14 games this year and have walked away with the win 10 times (71.4%) in those games. Iowa State’s games this year have hit the over on 11 of 34 set point totals.

Pittsburgh has 23 wins against the spread in 34 games this season. The Panthers have won eight of the 16 games they were the underdog on the moneyline this season (50%). Pittsburgh’s games this season have gone over the point total 21 times in 34 opportunities (61.8%).

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Iowa State vs. Pittsburgh Key Players to Watch

Iowa State

Jaren Holmes averages a team-best 13.4 points per game. He is also posting 3.7 rebounds and 3.3 assists, shooting 39.1% from the floor and 34.5% from beyond the arc with 1.3 made 3-pointers per contest. Tamin Lipsey leads the Cyclones at 4.5 assists per game, while also putting up 3.8 rebounds and 7.4 points. Gabe Kalscheur posts 12.9 points, 2.5 rebounds and 1.6 assists per contest, shooting 40.4% from the field and 36.4% from beyond the arc with 2.3 made 3-pointers per game.
Osun Osunniyi is tops on the Cyclones at 4 rebounds per contest, while also posting 1.1 assists and 8.5 points.


Jamarius Burton is posting 15.3 points, 4.8 rebounds and 4.3 assists per game, making 49.9% of his shots from the field. Blake Hinson leads the Panthers in scoring (15.5 points per game) and rebounding (6.1), and averages 1.2 assists. He also averages 0.6 steals and 0.5 blocked shots. Nelly Cummings is posting a team-leading 4.8 assists per game. And he is contributing 11.1 points and 2.6 rebounds, making 41.7% of his shots from the field and 36% from 3-point range, with 1.7 triples per game. Greg Elliott gives the Panthers 10.5 points, 3.8 rebounds and 1.2 assists per game. He also averages 0.8 steals and 0.2 blocked shots.

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What you need to know about the Iowa State Cyclones

The Cyclones have been led by their defense, as they rank 22nd-best in college basketball by giving up only 62.8 points per game. They rank 267th in college basketball in points scored (68.4 per contest). Iowa State ranks 18th-best in college basketball by allowing only 27.6 rebounds per game. It ranks 245th in college basketball by pulling down 30.7 boards per contest.

Iowa State is draining 6.5 three-pointers per game (279th-ranked in college basketball) this season, while sporting a 33.9% three-point percentage (193rd-ranked). With 7.7 treys conceded per game, the Cyclones rank 240th in the country. They are ceding a 33.8% shooting percentage from beyond the arc, which ranks 185th in college basketball.

The Cyclones have a 3-7 record against the spread while going 3-7 overall over their past 10 games. Iowa State has gone over the total in three of its past 10 outings. On offense, Iowa State has struggled over its last 10 games, scoring 63.4 points per contest over that span compared to the 68.4 it has put up over the course of this season. The past 10 games have seen Iowa State allow 3.8 more points per game (66.6) than its season-long average (62.8).

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What you need to know about the Pittsburgh Panthers

The Panthers score 75.6 points per game and give up 70.1, making them 81st in the country offensively and 176th defensively. In 2022-23, Pittsburgh is 98th in college basketball in rebounds (33 per game) and 208th in rebounds allowed (31.6).

In 2022-23 Pittsburgh is 25th-best in college basketball in 3-point makes (9.2 per game), and it ranks No. 68 in 3-point percentage (36.2%). The Panthers give up 7.7 3-pointers per game and concede 33.2% from beyond the arc, ranking 240th and 137th, respectively, in the country.

The Panthers have a 6-4 record against the spread while going 6-4 overall over their last 10 contests. Seven of Pittsburgh’s last 10 outings have hit the over. Pittsburgh is putting up 78.2 points per game in its past 10 games, compared to its season average of 75.6. The Panthers have played worse defensively in their previous 10 games, giving up 76.4 points per contest, 6.3 more points their than season average of 70.1.

Iowa State vs. Pittsburgh Prediction & Pick

Our prediction to win this matchup is Iowa State, and we predict that Pittsburgh will cover the spread (Iowa State -4.5). Finally, we see the scoring in this one going over the posted total of 131.5 points.

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How to bet Iowa State vs. Pittsburgh

You can bet on Iowa State vs. Pittsburgh at every legal online sportsbook. For more college basketball odds, including moneylines, spreads, over/under totals, check out the latest NCAA lines as well as our guide to the best college basketball betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Iowa State vs. Pittsburgh picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college basketball? Check out our complete guide to sports betting.


Matt Rooney

Matt comes from Chicago and has lived in the area his whole life. Graduated from and played football at Illinois Wesleyan University in Bloomington, IL while also serving as the director of student sports broadcasting. He writes for Betsperts as well as appears on several shows across the network.

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