Creighton vs DePaul Prediction: Odds, Picks, Best Bets – Saturday, March 4, 2023

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The DePaul Blue Demons (9-21, 3-16 Big East) hope to stop a four-game home losing skid when hosting the Creighton Bluejays (19-11, 13-6 Big East) on Saturday, March 4, 2023 at 9:00 PM ET.

The Bluejays are currently double-digit 12-point favorites against the Blue Demons. The matchup’s over/under is 146.

Creighton vs. DePaul Odds

Point Spread for Creighton vs. DePaul

The spread for this matchup is set at 12 points, with bookmakers listing Creighton as the favorite.

Creighton vs. DePaul Moneyline

As for the moneyline, Creighton has -809 odds to pick up the win, while DePaul is listed at +546 to claim victory.


Finally, the over/under for the game is set at 146 points.

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Game Time and How to Watch

  • Game Day: Saturday, March 4, 2023
  • Game Time: 9:00 PM ET
  • TV Channel: Fox Sports 1
  • Location: Chicago, Illinois
  • Arena: Wintrust Arena

Creighton vs. DePaul Betting Trends

Creighton has played 30 games, with 14 wins against the spread. The Bluejays have been favorites in 23 games this season and have come away with the win 18 times (78.3%) in those contests. Creighton’s games this year have gone over the total in 13 out of 30 opportunities (43.3%).

Against the spread, DePaul is 11-17-2 this season. The Blue Demons have won 14.3% of the games this season they were the moneyline underdog (3-18). DePaul’s games this season have gone over the point total 14 times in 30 opportunities (46.7%).

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Creighton vs. DePaul Key Players to Watch


Baylor Scheierman is tops on his team in rebounds per game (8.2), and also averages 13 points and 3.1 assists. Defensively, he posts 1.1 steals and 0.2 blocked shots. Ryan Kalkbrenner paces his squad in points per contest (14.9), and also averages 6.4 rebounds and 1.3 assists. Defensively, he delivers 0.6 steals and 2.3 blocked shots. Trey Alexander puts up 13.4 points, 4 rebounds and 2.6 assists per game. At the other end, he posts 1 steal and 0.5 blocked shots. Ryan Nembhard leads the Bluejays at 5 assists per game, while also averaging 3.7 rebounds and 11.7 points.


Javan Johnson gets the Blue Demons 14.1 points, 4.5 rebounds and 2.4 assists per game. He also posts 0.7 steals and 0.9 blocked shots. Eral Penn paces the Blue Demons in rebounding (7 per game), and puts up 8.7 points and 0.7 assists. He also puts up 0.7 steals and 1 block. Da’Sean Nelson is putting up 10.5 points, 5.1 rebounds and 1.8 assists per contest, making 54.3% of his shots from the field.

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What you need to know about the Creighton Bluejays

Creighton has compiled an 8-11-0 conference record against the spread this season. The Bluejays are putting up 76.6 points per game (63rd-ranked in college basketball) this season, while giving up 67.8 points per contest (112th-ranked). With 34.8 rebounds per game, Creighton is 34th in the country. It gives up 30.9 rebounds per contest, which ranks 173rd in college basketball.

When playing at home, the Bluejays are posting eight more points per game (79.3) than they are away from home (71.3). Creighton is 40th in the country with 8.9 threes per game this season. Meanwhile, it ranks 96th with a 35.7% shooting percentage from three-point land. The Bluejays are ceding 6.2 treys per game (52nd-ranked in college basketball) this season, while allowing a 33.4% three-point percentage (155th-ranked).

The Bluejays have gone 7-3 in their last 10 contests, with a 4-6 record against the spread in that span. Four of Creighton’s last 10 games have hit the over. Creighton has seen a decrease in scoring recently, racking up 74.4 points per game in its last 10 outings, 2.2 points fewer than the 76.6 it has scored this year. Creighton has been tougher on defense as of late, allowing 66.8 points per game during its past 10 outings compared to the 67.8 points per game its opponents are averaging over the 2022-23 season.

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What you need to know about the DePaul Blue Demons

A total of eight DePaul conference games this season have gone over the point total. In 2022-23, the Blue Demons are 192nd in the country offensively (71 points scored per game) and 16th-worst defensively (77.1 points allowed). In 2022-23, DePaul is 286th in college basketball in rebounds (29.8 per game) and 0-worst in rebounds conceded (35.9).

At home, the Blue Demons score 75.8 points per game. On the road, they score 66.4. Beyond the arc, DePaul is 77th in the nation in 3-pointers made per game (8.3). It is 71st in 3-point percentage at 36.1%. The Blue Demons give up 7.3 3-pointers per game and concede 34.8% from beyond the arc, ranking 195th and 247th, respectively, in the country.

The Blue Demons have covered the spread twice, and are 0-10 overall, over their last 10 contests. DePaul has gone over the total in six of its past 10 games. While DePaul is posting 71 points per game in 2022-23, it has fallen short of that over its past 10 games, producing 70.2 points per contest. The Blue Demons are allowing 82.1 points per game in their past 10 games, compared to their season average of 77.1 points allowed.

Creighton vs. DePaul Prediction & Pick

Our prediction to win this game is Creighton, and we project that DePaul will cover the spread (Creighton -12). Finally, we see the scoring in this one going over the posted total of 146 points.

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How to bet Creighton vs. DePaul

You can bet on Creighton vs. DePaul at every legal online sportsbook. For more college basketball odds, including moneylines, spreads, over/under totals, check out the latest NCAA lines as well as our guide to the best college basketball betting sites.

And if you wanted to check out how much you could win on a $10 bet if you parlayed today’s Creighton vs. DePaul picks, don’t forget to check out our free parlay calculator.

Not sure what a parlay is? Or even how to bet on college basketball? Check out our complete guide to sports betting.


Dan Weiner

Hailing from Atlanta and attending college at the University of Texas, Dan is passionate about sports, particularly college football and soccer. He's a diehard Atlanta pro sports and Texas Longhorns fan. He likes every sport and will watch anything and everything the weirder the better. He joined Betsperts after an 11 year career in television production at ESPN.

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